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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 2 (260/260 = 100%)† (Homo sapiens (Human)) | BDBM50335808 (2,5-Dihydroxybenzoate, VI | 2,5-dihydroxybenzoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay | Bioorg Med Chem 21: 1564-9 (2013) Article DOI: 10.1016/j.bmc.2012.05.019 BindingDB Entry DOI: 10.7270/Q29888CF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Carbonic anhydrase 2 (260/260 = 100%)† (Homo sapiens (Human)) | BDBM50335808 (2,5-Dihydroxybenzoate, VI | 2,5-dihydroxybenzoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Fox Chase Cancer Center Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase isozyme 2 pre-incubated for 10 mins before 4-nitrophenylacetate substrate addition | J Med Chem 60: 128-145 (2017) Article DOI: 10.1021/acs.jmedchem.6b00725 BindingDB Entry DOI: 10.7270/Q2RX9F10 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
