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PDB code 4E5Q

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 2 hits Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2

  (260/260 = 100%)
(Homo sapiens (Human))
BDBM50147624
PNG
(CHEBI:28024 | CYANATE | Cyanate Ion)
Show InChI InChI=1S/CHNO/c2-1-3/h3H
PDB
MMDB

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MCE
KEGG
PC cid
PC sid
PDB
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Similars

Article
PubMed
3.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human CA2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assay


Bioorg Med Chem Lett 25: 5485-9 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.074
BindingDB Entry DOI: 10.7270/Q2K93BJF
More data for this
Ligand-Target Pair
Carbonic anhydrase 2

  (260/260 = 100%)
(Homo sapiens (Human))
BDBM50147624
PNG
(CHEBI:28024 | CYANATE | Cyanate Ion)
Show InChI InChI=1S/CHNO/c2-1-3/h3H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
KEGG
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
3.00E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 26: 1406-10 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.072
BindingDB Entry DOI: 10.7270/Q2W95C24
More data for this
Ligand-Target Pair

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output