Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
4,4'-diapophytoene synthase (287/287 = 100%)† (Staphylococcus aureus) | BDBM50388397 (CHEMBL39581) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Urbana-Champaign Curated by ChEMBL | Assay Description Inhibition of Staphylococcus aureus ATCC 27659 dehydrosqualene synthase expressed in Escherichia coli BL21(DE3) after 30 mins by spectrophotometric a... | J Med Chem 55: 4367-72 (2012) Article DOI: 10.1021/jm300208p BindingDB Entry DOI: 10.7270/Q2Z320QH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |