Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (309/309 = 100%)† (Homo sapiens (Human)) | BDBM50341627 (3-(4-Methylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 0.930 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of purified recombinant c-Met after 60 mins by ELISA | J Med Chem 54: 2127-42 (2011) Article DOI: 10.1021/jm101340q BindingDB Entry DOI: 10.7270/Q2DR2VTS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |