Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Hepatocyte growth factor receptor (309/309 = 100%)† (Homo sapiens (Human)) | BDBM50391660 (CHEMBL2148143) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of recombinant c-Met kinase domain using poly(Glu,Tyr) as substrate after 60 mins by ELISA | Bioorg Med Chem Lett 22: 6368-72 (2012) Article DOI: 10.1016/j.bmcl.2012.08.075 BindingDB Entry DOI: 10.7270/Q2X0684C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |