Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nicotinamide phosphoribosyltransferase (491/491 = 100%)† (Homo sapiens (Human)) | BDBM180267 (US9676721, 91 2-cyano-3-(pyridin-4-yl)-1-[(4-{[3-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | 7.5 | 25 |
FORMA TM, LLC US Patent | Assay Description The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The... | US Patent US9676721 (2017) BindingDB Entry DOI: 10.7270/Q2VD6WMM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |