Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hexokinase-4 (450/450 = 100%)† (Homo sapiens (Human)) | BDBM50441143 (CHEMBL2430855) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 2.64E+3 | n/a | n/a | n/a | n/a |
Array BioPharma Curated by ChEMBL | Assay Description Allosteric activation of human glucokinase using glucose as substrate measured every 10 secs for 5 mins | J Med Chem 56: 7669-78 (2013) Article DOI: 10.1021/jm401116k BindingDB Entry DOI: 10.7270/Q2XP76BH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |