Identical Ligands in BindingDB

Found 3 hits Enzyme Inhibition Constant Data   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CARBONIC ANHYDRASE   (227/228 > 99%)† (Helicobacter pylori J99)	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kochi Medical School					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...				J Med Chem 49: 2117-26 (2006) Article DOI: 10.1021/jm0512600 BindingDB Entry DOI: 10.7270/Q2ZS2TQB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-carbonic anhydrase   (225/228 = 99%)† (Helicobacter pylori (strain G27))	BDBM26979 (CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...) Show SMILES [Cl-] Show InChI InChI=1S/ClH/h1H/p-1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	2.70E+6	-14.4	n/a	n/a	n/a	n/a	n/a	7.5	20
Universit£ degli Studi di Firenze					Assay Description Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay				Bioorg Med Chem 24: 3413-7 (2016) Article DOI: 10.1016/j.bmc.2016.05.029 BindingDB Entry DOI: 10.7270/Q2W9583B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-carbonic anhydrase   (225/228 = 99%)† (Helicobacter pylori)	BDBM26979 (CHEMBL69710 | Cl- | POTASSIUM CHLORIDE | SODIUM CH...) Show SMILES [Cl-] Show InChI InChI=1S/ClH/h1H/p-1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	2.70E+6	-14.7	n/a	n/a	n/a	n/a	n/a	7.5	25
Università degli Studi di Firenze					Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...				J Enzyme Inhib Med Chem 28: 388-91 (2013) Article DOI: 10.3109/14756366.2011.649268 BindingDB Entry DOI: 10.7270/Q2S75F7K
					More data for this Ligand-Target Pair				3D Structure (crystal)

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