Affinity Data by PDB ID

PDB code 5F8P

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase FTO [31-505] (471/472 > 99%)^† (Homo sapiens (Human))	BDBM181057 (CHTB) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.92E+4	n/a	n/a	n/a	n/a	7.5	42
Basic Medical College of Zhengzhou University					Assay Description In vitro enzymatic activity assays were performed as previously described. The15-mer ssRNA (5'-CUUGUCA(m6A)CAGCAGA-3') was used as a substrate to eva...				Biochemistry 55: 1516-22 (2016) Article DOI: 10.1021/acs.biochem.6b00023 BindingDB Entry DOI: 10.7270/Q27W69Z9
Basic Medical College of Zhengzhou University					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output