Found 63 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM3532
(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)Show InChI InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
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| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074743
(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)Show InChI InChI=1S/C15H10ClNO3/c16-9-3-1-2-8(4-9)11-7-17-12-5-10(18)6-13(19)14(12)15(11)20/h1-7,18-19H,(H,17,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074742
(CHEMBL7866 | [3-(3-Chloro-phenyl)-5-hydroxy-7-meth...)Show SMILES COC(=O)Cn1cc(-c2cccc(Cl)c2)c(=O)c2c(O)cc(OC)cc12 Show InChI InChI=1S/C19H16ClNO5/c1-25-13-7-15-18(16(22)8-13)19(24)14(9-21(15)10-17(23)26-2)11-4-3-5-12(20)6-11/h3-9,22H,10H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
MMDB
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM3532
(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)Show InChI InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) | PDB
MMDB
Reactome pathway
KEGG
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| Article
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM3532
(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)Show InChI InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) | PDB
MMDB
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CHEMBL
MCE
MMDB
PC cid
PC sid
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| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM3532
(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)Show InChI InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) | PDB
KEGG
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CHEMBL
MCE
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| Article
PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074740
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)Show InChI InChI=1S/C17H14ClNO3/c1-19-9-13(10-4-3-5-11(18)6-10)17(21)16-14(19)7-12(22-2)8-15(16)20/h3-9,20H,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM19459
(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | PDB
MMDB
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CHEMBL
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MCE
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PC cid
PC sid
PDB
UniChem
Patents
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| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074741
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)Show InChI InChI=1S/C16H11ClO4/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-3-2-4-10(17)5-9/h2-8,18H,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074739
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)Show SMILES COc1cc(O)c2c(c1)n(CCc1ccccc1)cc(-c1cccc(Cl)c1)c2=O Show InChI InChI=1S/C24H20ClNO3/c1-29-19-13-21-23(22(27)14-19)24(28)20(17-8-5-9-18(25)12-17)15-26(21)11-10-16-6-3-2-4-7-16/h2-9,12-15,27H,10-11H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074743
(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)Show InChI InChI=1S/C15H10ClNO3/c16-9-3-1-2-8(4-9)11-7-17-12-5-10(18)6-13(19)14(12)15(11)20/h1-7,18-19H,(H,17,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM3532
(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)Show InChI InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
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CHEMBL
MCE
MMDB
PC cid
PC sid
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UniChem
Patents
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| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074740
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)Show InChI InChI=1S/C17H14ClNO3/c1-19-9-13(10-4-3-5-11(18)6-10)17(21)16-14(19)7-12(22-2)8-15(16)20/h3-9,20H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074740
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)Show InChI InChI=1S/C17H14ClNO3/c1-19-9-13(10-4-3-5-11(18)6-10)17(21)16-14(19)7-12(22-2)8-15(16)20/h3-9,20H,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074739
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)Show SMILES COc1cc(O)c2c(c1)n(CCc1ccccc1)cc(-c1cccc(Cl)c1)c2=O Show InChI InChI=1S/C24H20ClNO3/c1-29-19-13-21-23(22(27)14-19)24(28)20(17-8-5-9-18(25)12-17)15-26(21)11-10-16-6-3-2-4-7-16/h2-9,12-15,27H,10-11H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074739
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)Show SMILES COc1cc(O)c2c(c1)n(CCc1ccccc1)cc(-c1cccc(Cl)c1)c2=O Show InChI InChI=1S/C24H20ClNO3/c1-29-19-13-21-23(22(27)14-19)24(28)20(17-8-5-9-18(25)12-17)15-26(21)11-10-16-6-3-2-4-7-16/h2-9,12-15,27H,10-11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50074743
(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)Show InChI InChI=1S/C15H10ClNO3/c16-9-3-1-2-8(4-9)11-7-17-12-5-10(18)6-13(19)14(12)15(11)20/h1-7,18-19H,(H,17,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074742
(CHEMBL7866 | [3-(3-Chloro-phenyl)-5-hydroxy-7-meth...)Show SMILES COC(=O)Cn1cc(-c2cccc(Cl)c2)c(=O)c2c(O)cc(OC)cc12 Show InChI InChI=1S/C19H16ClNO5/c1-25-13-7-15-18(16(22)8-13)19(24)14(9-21(15)10-17(23)26-2)11-4-3-5-12(20)6-11/h3-9,22H,10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50074740
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)Show InChI InChI=1S/C17H14ClNO3/c1-19-9-13(10-4-3-5-11(18)6-10)17(21)16-14(19)7-12(22-2)8-15(16)20/h3-9,20H,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074743
(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)Show InChI InChI=1S/C15H10ClNO3/c16-9-3-1-2-8(4-9)11-7-17-12-5-10(18)6-13(19)14(12)15(11)20/h1-7,18-19H,(H,17,20) | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM50074740
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)Show InChI InChI=1S/C17H14ClNO3/c1-19-9-13(10-4-3-5-11(18)6-10)17(21)16-14(19)7-12(22-2)8-15(16)20/h3-9,20H,1-2H3 | PDB
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UniChem
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074740
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)Show InChI InChI=1S/C17H14ClNO3/c1-19-9-13(10-4-3-5-11(18)6-10)17(21)16-14(19)7-12(22-2)8-15(16)20/h3-9,20H,1-2H3 | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM50074743
(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)Show InChI InChI=1S/C15H10ClNO3/c16-9-3-1-2-8(4-9)11-7-17-12-5-10(18)6-13(19)14(12)15(11)20/h1-7,18-19H,(H,17,20) | PDB
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PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074739
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-phenethy...)Show SMILES COc1cc(O)c2c(c1)n(CCc1ccccc1)cc(-c1cccc(Cl)c1)c2=O Show InChI InChI=1S/C24H20ClNO3/c1-29-19-13-21-23(22(27)14-19)24(28)20(17-8-5-9-18(25)12-17)15-26(21)11-10-16-6-3-2-4-7-16/h2-9,12-15,27H,10-11H2,1H3 | PDB
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PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM19459
(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50074742
(CHEMBL7866 | [3-(3-Chloro-phenyl)-5-hydroxy-7-meth...)Show SMILES COC(=O)Cn1cc(-c2cccc(Cl)c2)c(=O)c2c(O)cc(OC)cc12 Show InChI InChI=1S/C19H16ClNO5/c1-25-13-7-15-18(16(22)8-13)19(24)14(9-21(15)10-17(23)26-2)11-4-3-5-12(20)6-11/h3-9,22H,10H2,1-2H3 | PDB
MMDB
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| CHEMBL
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UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074741
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)Show InChI InChI=1S/C16H11ClO4/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-3-2-4-10(17)5-9/h2-8,18H,1H3 | PDB
Reactome pathway
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UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074746
(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)Show InChI InChI=1S/C17H13ClO4/c1-20-12-7-14(21-2)16-15(8-12)22-9-13(17(16)19)10-4-3-5-11(18)6-10/h3-9H,1-2H3 | PDB
Reactome pathway
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PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074742
(CHEMBL7866 | [3-(3-Chloro-phenyl)-5-hydroxy-7-meth...)Show SMILES COC(=O)Cn1cc(-c2cccc(Cl)c2)c(=O)c2c(O)cc(OC)cc12 Show InChI InChI=1S/C19H16ClNO5/c1-25-13-7-15-18(16(22)8-13)19(24)14(9-21(15)10-17(23)26-2)11-4-3-5-12(20)6-11/h3-9,22H,10H2,1-2H3 | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM50074742
(CHEMBL7866 | [3-(3-Chloro-phenyl)-5-hydroxy-7-meth...)Show SMILES COC(=O)Cn1cc(-c2cccc(Cl)c2)c(=O)c2c(O)cc(OC)cc12 Show InChI InChI=1S/C19H16ClNO5/c1-25-13-7-15-18(16(22)8-13)19(24)14(9-21(15)10-17(23)26-2)11-4-3-5-12(20)6-11/h3-9,22H,10H2,1-2H3 | PDB
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UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM19459
(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
Reactome pathway
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM3532
(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)Show InChI InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
Reactome pathway
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074743
(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)Show InChI InChI=1S/C15H10ClNO3/c16-9-3-1-2-8(4-9)11-7-17-12-5-10(18)6-13(19)14(12)15(11)20/h1-7,18-19H,(H,17,20) | PDB
MMDB
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UniChem
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PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
MMDB
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PubMed
| n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
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PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074742
(CHEMBL7866 | [3-(3-Chloro-phenyl)-5-hydroxy-7-meth...)Show SMILES COC(=O)Cn1cc(-c2cccc(Cl)c2)c(=O)c2c(O)cc(OC)cc12 Show InChI InChI=1S/C19H16ClNO5/c1-25-13-7-15-18(16(22)8-13)19(24)14(9-21(15)10-17(23)26-2)11-4-3-5-12(20)6-11/h3-9,22H,10H2,1-2H3 | PDB
MMDB
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UniChem
Similars
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PubMed
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
MMDB
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PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
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PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074741
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)Show InChI InChI=1S/C16H11ClO4/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-3-2-4-10(17)5-9/h2-8,18H,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Mus musculus) | BDBM50074746
(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)Show InChI InChI=1S/C17H13ClO4/c1-20-12-7-14(21-2)16-15(8-12)22-9-13(17(16)19)10-4-3-5-11(18)6-10/h3-9H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074748
(3-(3-Chloro-phenyl)-7-hydroxy-chromen-4-one | CHEM...)Show InChI InChI=1S/C15H9ClO3/c16-10-3-1-2-9(6-10)13-8-19-14-7-11(17)4-5-12(14)15(13)18/h1-8,17H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074741
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)Show InChI InChI=1S/C16H11ClO4/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-3-2-4-10(17)5-9/h2-8,18H,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50074742
(CHEMBL7866 | [3-(3-Chloro-phenyl)-5-hydroxy-7-meth...)Show SMILES COC(=O)Cn1cc(-c2cccc(Cl)c2)c(=O)c2c(O)cc(OC)cc12 Show InChI InChI=1S/C19H16ClNO5/c1-25-13-7-15-18(16(22)8-13)19(24)14(9-21(15)10-17(23)26-2)11-4-3-5-12(20)6-11/h3-9,22H,10H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM19459
(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50074744
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)Show InChI InChI=1S/C16H12ClNO3/c1-21-11-6-13-15(14(19)7-11)16(20)12(8-18-13)9-3-2-4-10(17)5-9/h2-8,19H,1H3,(H,18,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50074741
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)Show InChI InChI=1S/C16H11ClO4/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-3-2-4-10(17)5-9/h2-8,18H,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of p60 c-Src tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM3532
(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)Show InChI InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50074745
(3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one | ...)Show InChI InChI=1S/C15H9ClO4/c16-9-3-1-2-8(4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,17-18H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50074743
(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)Show InChI InChI=1S/C15H10ClNO3/c16-9-3-1-2-8(4-9)11-7-17-12-5-10(18)6-13(19)14(12)15(11)20/h1-7,18-19H,(H,17,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1/ABL2
(Homo sapiens (Human)) | BDBM50074741
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)Show InChI InChI=1S/C16H11ClO4/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-3-2-4-10(17)5-9/h2-8,18H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of v-Abl tyrosine kinase |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50074740
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1-methyl-1...)Show InChI InChI=1S/C17H14ClNO3/c1-19-9-13(10-4-3-5-11(18)6-10)17(21)16-14(19)7-12(22-2)8-15(16)20/h3-9,20H,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM50074741
(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-...)Show InChI InChI=1S/C16H11ClO4/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-3-2-4-10(17)5-9/h2-8,18H,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Protein kinase C alpha |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074746
(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)Show InChI InChI=1S/C17H13ClO4/c1-20-12-7-14(21-2)16-15(8-12)22-9-13(17(16)19)10-4-3-5-11(18)6-10/h3-9H,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074747
(3-(3-Chloro-phenyl)-1H-quinolin-4-one | CHEMBL7801)Show InChI InChI=1S/C15H10ClNO/c16-11-5-3-4-10(8-11)13-9-17-14-7-2-1-6-12(14)15(13)18/h1-9H,(H,17,18) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor-dependent phosphorylation |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50074746
(3-(3-Chloro-phenyl)-5,7-dimethoxy-chromen-4-one | ...)Show InChI InChI=1S/C17H13ClO4/c1-20-12-7-14(21-2)16-15(8-12)22-9-13(17(16)19)10-4-3-5-11(18)6-10/h3-9H,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NOVARTIS Limited
Curated by ChEMBL
| Assay Description
Inhibition of Epidermal growth factor receptor |
J Med Chem 42: 1018-26 (1999)
Article DOI: 10.1021/jm980551o
BindingDB Entry DOI: 10.7270/Q21835PV |
More data for this
Ligand-Target Pair | |
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