Found 13 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vitamin D3 receptor
(Homo sapiens (Human)) | BDBM36717
(1,25(OH)2D3)Show SMILES CC(CCCC(C)(C)O)C1CCC2CC(CCC12C)\C=C\C=C1\C[C@@H](C)C[C@H](C)C1=C |r| Show InChI InChI=1S/C30H50O/c1-21-18-23(3)24(4)26(19-21)12-8-11-25-15-17-30(7)27(20-25)13-14-28(30)22(2)10-9-16-29(5,6)31/h8,11-12,21-23,25,27-28,31H,4,9-10,13-20H2,1-3,5-7H3/b11-8+,26-12-/t21-,22?,23-,25?,27?,28?,30?/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 0.5 | -49.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid. |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D3 receptor
(Homo sapiens (Human)) | BDBM36722
(LG190178)Show SMILES CCC(CC)(c1ccc(OCC(O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 Show InChI InChI=1S/C28H40O5/c1-8-28(9-2,21-10-12-24(19(3)14-21)32-17-23(30)16-29)22-11-13-25(20(4)15-22)33-18-26(31)27(5,6)7/h10-15,23,29-30H,8-9,16-18H2,1-7H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 150 | -36.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid. |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D3 receptor
(Homo sapiens (Human)) | BDBM36718
(LG190090)Show SMILES CC(C)(C)C(=O)COc1ccc(cc1Cl)C(C)(C)c1ccc(OCC(=O)C(C)(C)C)c(Cl)c1 Show InChI InChI=1S/C27H34Cl2O4/c1-25(2,3)23(30)15-32-21-11-9-17(13-19(21)28)27(7,8)18-10-12-22(20(29)14-18)33-16-24(31)26(4,5)6/h9-14H,15-16H2,1-8H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+3 | >-31.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid. |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D3 receptor
(Homo sapiens (Human)) | BDBM36721
(LG190176)Show SMILES CCC(CC)(c1ccc(OCC2CO2)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 Show InChI InChI=1S/C28H38O4/c1-8-28(9-2,21-10-12-24(19(3)14-21)31-17-23-16-30-23)22-11-13-25(20(4)15-22)32-18-26(29)27(5,6)7/h10-15,23H,8-9,16-18H2,1-7H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+3 | >-31.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid. |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D3 receptor
(Homo sapiens (Human)) | BDBM36720
(LG190155)Show SMILES CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 Show InChI InChI=1S/C31H44O4/c1-11-31(12-2,23-13-15-25(21(3)17-23)34-19-27(32)29(5,6)7)24-14-16-26(22(4)18-24)35-20-28(33)30(8,9)10/h13-18H,11-12,19-20H2,1-10H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+3 | >-31.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid. |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D3 receptor
(Homo sapiens (Human)) | BDBM36719
(LG190119)Show SMILES Cc1cc(ccc1OCC(=O)C(C)(C)C)C1(CCCCC1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 Show InChI InChI=1S/C32H44O4/c1-22-18-24(12-14-26(22)35-20-28(33)30(3,4)5)32(16-10-9-11-17-32)25-13-15-27(23(2)19-25)36-21-29(34)31(6,7)8/h12-15,18-19H,9-11,16-17,20-21H2,1-8H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+3 | >-31.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid. |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D-binding protein
(Rattus norvegicus) | BDBM36717
(1,25(OH)2D3)Show SMILES CC(CCCC(C)(C)O)C1CCC2CC(CCC12C)\C=C\C=C1\C[C@@H](C)C[C@H](C)C1=C |r| Show InChI InChI=1S/C30H50O/c1-21-18-23(3)24(4)26(19-21)12-8-11-25-15-17-30(7)27(20-25)13-14-28(30)22(2)10-9-16-29(5,6)31/h8,11-12,21-23,25,27-28,31H,4,9-10,13-20H2,1-3,5-7H3/b11-8+,26-12-/t21-,22?,23-,25?,27?,28?,30?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL). |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D-binding protein
(Homo sapiens (Human)) | BDBM36717
(1,25(OH)2D3)Show SMILES CC(CCCC(C)(C)O)C1CCC2CC(CCC12C)\C=C\C=C1\C[C@@H](C)C[C@H](C)C1=C |r| Show InChI InChI=1S/C30H50O/c1-21-18-23(3)24(4)26(19-21)12-8-11-25-15-17-30(7)27(20-25)13-14-28(30)22(2)10-9-16-29(5,6)31/h8,11-12,21-23,25,27-28,31H,4,9-10,13-20H2,1-3,5-7H3/b11-8+,26-12-/t21-,22?,23-,25?,27?,28?,30?/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL). |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D-binding protein
(Homo sapiens (Human)) | BDBM36721
(LG190176)Show SMILES CCC(CC)(c1ccc(OCC2CO2)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 Show InChI InChI=1S/C28H38O4/c1-8-28(9-2,21-10-12-24(19(3)14-21)31-17-23-16-30-23)22-11-13-25(20(4)15-22)32-18-26(29)27(5,6)7/h10-15,23H,8-9,16-18H2,1-7H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL). |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D-binding protein
(Homo sapiens (Human)) | BDBM36720
(LG190155)Show SMILES CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 Show InChI InChI=1S/C31H44O4/c1-11-31(12-2,23-13-15-25(21(3)17-23)34-19-27(32)29(5,6)7)24-14-16-26(22(4)18-24)35-20-28(33)30(8,9)10/h13-18H,11-12,19-20H2,1-10H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL). |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D-binding protein
(Homo sapiens (Human)) | BDBM36718
(LG190090)Show SMILES CC(C)(C)C(=O)COc1ccc(cc1Cl)C(C)(C)c1ccc(OCC(=O)C(C)(C)C)c(Cl)c1 Show InChI InChI=1S/C27H34Cl2O4/c1-25(2,3)23(30)15-32-21-11-9-17(13-19(21)28)27(7,8)18-10-12-22(20(29)14-18)33-16-24(31)26(4,5)6/h9-14H,15-16H2,1-8H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL). |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D-binding protein
(Homo sapiens (Human)) | BDBM36719
(LG190119)Show SMILES Cc1cc(ccc1OCC(=O)C(C)(C)C)C1(CCCCC1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 Show InChI InChI=1S/C32H44O4/c1-22-18-24(12-14-26(22)35-20-28(33)30(3,4)5)32(16-10-9-11-17-32)25-13-15-27(23(2)19-25)36-21-29(34)31(6,7)8/h12-15,18-19H,9-11,16-17,20-21H2,1-8H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL). |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |
Vitamin D-binding protein
(Homo sapiens (Human)) | BDBM36722
(LG190178)Show SMILES CCC(CC)(c1ccc(OCC(O)CO)c(C)c1)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 Show InChI InChI=1S/C28H40O5/c1-8-28(9-2,21-10-12-24(19(3)14-21)32-17-23(30)16-29)22-11-13-25(20(4)15-22)33-18-26(31)27(5,6)7/h10-15,23,29-30H,8-9,16-18H2,1-7H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 4 |
Ligand Pharmaceuticals, Inc
| Assay Description DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL). |
Chem Biol 6: 265-75 (1999)
Article DOI: 10.1016/S1074-5521(99)80072-6 BindingDB Entry DOI: 10.7270/Q2NC5ZJZ |
More data for this Ligand-Target Pair | |