Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2555 (4-({6-[2-(4-aminophenyl)ethyl]-4-hydroxy-2-oxo-6-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2543 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2541 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2538 (6-Alkyl-5,6-Dihydropyran-2-one 14 | [5-tert-butyl-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2539 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2548 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2545 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2547 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM459 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM461 (4-({6-[2-(4-aminophenyl)ethyl]-4-hydroxy-2-oxo-6-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2557 (5-tert-butyl-4-{[4-hydroxy-2-oxo-6-(2-phenylethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM462 (4-({6-[2-(4-aminophenyl)ethyl]-4-hydroxy-2-oxo-6-(...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2549 (5-tert-butyl-4-({6-cyclohexyl-4-hydroxy-6-[2-(4-hy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM460 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2540 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2183 ((3-(2-tert-Butyl-4-hydroxy-5-methyl-phenylsulfanyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2542 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM463 (5-tert-butyl-4-{[4-hydroxy-2-oxo-6-(2-phenylethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2551 (5-tert-butyl-4-({6-cyclohexyl-4-hydroxy-6-[2-(4-hy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2550 (5-tert-butyl-4-({6-cyclohexyl-4-hydroxy-6-[2-(4-hy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM2552 (5-tert-butyl-4-({4-hydroxy-6-[2-(4-hydroxyphenyl)e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | 6.2 | 37 |
Parke-Davis Pharmaceutical Research | Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)... | Bioorg Med Chem Lett 9: 2217-22 (1999) Article DOI: 10.1016/s0960-894x(99)00360-1 BindingDB Entry DOI: 10.7270/Q2TQ5ZQ6 | |||||||||||
More data for this Ligand-Target Pair |