Affinity Data by PubMed id=10509928

PubMed code 10509928

Found 31 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081496 (5-((S)-1-Azetidin-2-ylmethoxy)-pyrimidine \| CHEMBL...) Show SMILES C(Oc1cncnc1)[C@@H]1CCN1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50049756 (3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridine \|...) Show SMILES CN1CCC[C@H]1COc1cccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081490 (5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyrimidine...) Show SMILES CN1CCC[C@H]1COc1cncnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081484 (3-((S)-1-Methyl-pyrrolidin-3-yloxy)-pyridine \| CHE...) Show SMILES CN1CC[C@@H](C1)Oc1cccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081483 (3-((R)-1-Methyl-pyrrolidin-3-yloxy)-pyridine \| CHE...) Show SMILES CN1CC[C@H](C1)Oc1cccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081487 (5-((S)-1-Methyl-azetidin-2-ylmethoxy)-pyrimidine \|...) Show SMILES CN1CC[C@H]1COc1cncnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081473 (5-(1-Methyl-pyrrolidin-3-yloxy)-pyrimidine \| CHEMB...) Show SMILES CN1CCC(C1)Oc1cncnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081476 (3-((S)-1-Azetidin-2-ylmethoxy)-6-chloro-pyridazine...) Show SMILES Clc1ccc(OC[C@@H]2CCN2)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081475 (2-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyrazine \|...) Show SMILES CN1CCC[C@H]1COc1cnccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081478 (3-((S)-1-Methyl-azetidin-2-ylmethoxy)-pyridazine \|...) Show SMILES CN1CC[C@H]1COc1cccnn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081497 (3-Chloro-6-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-p...) Show SMILES CN1CCC[C@H]1COc1ccc(Cl)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081479 (3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridazine...) Show SMILES CN1CCC[C@H]1COc1cccnn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081477 (3-Chloro-6-(1-methyl-pyrrolidin-3-yloxy)-pyridazin...) Show SMILES CN1CCC(C1)Oc1ccc(Cl)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081474 (3-Chloro-6-((S)-1-methyl-azetidin-2-ylmethoxy)-pyr...) Show SMILES CN1CC[C@H]1COc1ccc(Cl)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081481 (3-Chloro-6-((R)-1-methyl-pyrrolidin-2-ylmethoxy)-p...) Show SMILES CN1CCC[C@@H]1COc1ccc(Cl)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081486 (2-(2-Pyrrolidin-1-yl-ethoxy)-pyridine \| CHEMBL9297...) Show SMILES C(CN1CCCC1)Oc1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081480 (3-(2-Pyrrolidin-1-yl-ethoxy)-pyridine \| CHEMBL3284...) Show SMILES C(CN1CCCC1)Oc1cccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081485 (2-(1-Methyl-pyrrolidin-3-yloxy)-pyrazine \| CHEMBL9...) Show SMILES CN1CCC(C1)Oc1cnccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	359	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081488 (2-((R)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyrazine \|...) Show SMILES CN1CCC[C@@H]1COc1cnccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	406	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081498 (2-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridine \|...) Show SMILES CN1CCC[C@H]1COc1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	495	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081494 (2-(2-Pyrrolidin-1-yl-ethoxy)-pyrazine \| CHEMBL9392...) Show SMILES C(CN1CCCC1)Oc1cnccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081495 (2-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyrimidine...) Show SMILES CN1CCC[C@H]1COc1ncccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081491 (3-Chloro-6-(2-pyrrolidin-1-yl-ethoxy)-pyridazine \|...) Show SMILES Clc1ccc(OCCN2CCCC2)nn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081489 (2-(2-Pyrrolidin-1-yl-ethoxy)-pyrimidine \| CHEMBL94...) Show SMILES C(CN1CCCC1)Oc1ncccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081492 (4-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridine \|...) Show SMILES CN1CCC[C@H]1COc1ccncc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081493 (2-(1-Methyl-pyrrolidin-3-yloxy)-pyridine \| CHEMBL8...) Show SMILES CN1CCC(C1)Oc1ccccn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50081496 (5-((S)-1-Azetidin-2-ylmethoxy)-pyrimidine \| CHEMBL...) Show SMILES C(Oc1cncnc1)[C@@H]1CCN1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [125I]-alpha-BgT binding to rat brain membran...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50081487 (5-((S)-1-Methyl-azetidin-2-ylmethoxy)-pyrimidine \|...) Show SMILES CN1CC[C@H]1COc1cncnc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [125I]-alpha-BgT binding to rat brain membran...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50081484 (3-((S)-1-Methyl-pyrrolidin-3-yloxy)-pyridine \| CHE...) Show SMILES CN1CC[C@@H](C1)Oc1cccnc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [125I]-alpha-BgT binding to rat brain membran...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-10 (Rattus norvegicus)	BDBM50081483 (3-((R)-1-Methyl-pyrrolidin-3-yloxy)-pyridine \| CHE...) Show SMILES CN1CC[C@H](C1)Oc1cccnc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [125I]-alpha-BgT binding to rat brain membran...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50081482 (3-(1-Methyl-pyrrolidin-3-yloxymethyl)-pyridine \| C...) Show SMILES CN1CCC(C1)OCc1cccnc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%