Affinity Data by PubMed id=10543887

PubMed code 10543887

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50082041 (4-iminomethylphenyl 4,4-dimethyl-6-chromanecarboxy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR alpha				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50082042 (CHEMBL139536 \| N-(2,2,4,4-Tetramethyl-thiochroman-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	225	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR alpha				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50082041 (4-iminomethylphenyl 4,4-dimethyl-6-chromanecarboxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR beta				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Homo sapiens (Human))	BDBM50082041 (4-iminomethylphenyl 4,4-dimethyl-6-chromanecarboxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR gamma				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Mus musculus)	BDBM50082041 (4-iminomethylphenyl 4,4-dimethyl-6-chromanecarboxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	294	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation of CV-1 cells expressing murine Retinoid X receptor RXR alpha				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Homo sapiens (Human))	BDBM50082042 (CHEMBL139536 \| N-(2,2,4,4-Tetramethyl-thiochroman-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	152	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR gamma				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Mus musculus)	BDBM50082042 (CHEMBL139536 \| N-(2,2,4,4-Tetramethyl-thiochroman-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	68	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation of CV-1 cells expressing murine Retinoid X receptor RXR beta				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Mus musculus)	BDBM50082041 (4-iminomethylphenyl 4,4-dimethyl-6-chromanecarboxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation of CV-1 cells expressing murine Retinoid X receptor RXR beta				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Mus musculus)	BDBM50082041 (4-iminomethylphenyl 4,4-dimethyl-6-chromanecarboxy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation of CV-1 cells expressing murine Retinoid X receptor RXR gamma				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Homo sapiens (Human))	BDBM50082042 (CHEMBL139536 \| N-(2,2,4,4-Tetramethyl-thiochroman-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation in CV-1 cells expressing human Retinoic acid receptor RAR beta				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Mus musculus)	BDBM50082042 (CHEMBL139536 \| N-(2,2,4,4-Tetramethyl-thiochroman-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	302	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation of CV-1 cells expressing murine Retinoid X receptor RXR gamma				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Mus musculus)	BDBM50082042 (CHEMBL139536 \| N-(2,2,4,4-Tetramethyl-thiochroman-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
University of Oklahoma Health Sciences Center Curated by ChEMBL					Assay Description Transcriptional activation of CV-1 cells expressing murine Retinoid X receptor RXR alpha				J Med Chem 42: 4434-45 (1999) BindingDB Entry DOI: 10.7270/Q2891530
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%