Found 22 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408794
(CHEMBL147284)Show InChI InChI=1S/C15H15NO2/c16-10-12-6-8-14(9-7-12)15(17)18-11-13-4-2-1-3-5-13/h1-9H,10-11,16H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408788
(CHEMBL147170)Show InChI InChI=1S/C15H14ClNO2/c16-14-7-3-12(4-8-14)10-19-15(18)13-5-1-11(9-17)2-6-13/h1-8H,9-10,17H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 3.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408777
(CHEMBL151826)Show InChI InChI=1S/C18H16N2O/c19-12-13-8-10-15(11-9-13)18(21)20-17-7-3-5-14-4-1-2-6-16(14)17/h1-11H,12,19H2,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description The compound was tested for inhibition of the proteolytic enzyme trypsin. |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408789
(CHEMBL149837)Show InChI InChI=1S/C14H14N2O/c15-10-11-6-8-12(9-7-11)14(17)16-13-4-2-1-3-5-13/h1-9H,10,15H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408776
(CHEMBL147399)Show InChI InChI=1S/C14H21NO2/c1-2-3-4-5-10-17-14(16)13-8-6-12(11-15)7-9-13/h6-9H,2-5,10-11,15H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408783
(CHEMBL357538)Show InChI InChI=1S/C16H18N2O/c17-12-14-6-8-15(9-7-14)16(19)18-11-10-13-4-2-1-3-5-13/h1-9H,10-12,17H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM10999
(Benzenemethanamine | Bn-NH2 | CHEMBL522 | benzylam...)Show InChI InChI=1S/C7H9N/c8-6-7-4-2-1-3-5-7/h1-5H,6,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Similars
| PubMed
| 3.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description The compound was tested for inhibition of the proteolytic enzyme trypsin. |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408795
(CHEMBL357501)Show InChI InChI=1S/C10H13NO2/c1-2-13-10(12)9-5-3-8(7-11)4-6-9/h3-6H,2,7,11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PubMed
| 3.57E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408787
(CHEMBL149440)Show InChI InChI=1S/C8H10N2O/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H2,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| 3.99E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408779
(CHEMBL146898)Show InChI InChI=1S/C14H15NO/c15-10-12-6-8-14(9-7-12)16-11-13-4-2-1-3-5-13/h1-9H,10-11,15H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408782
(CHEMBL149190)Show InChI InChI=1S/C15H16N2O/c16-10-12-6-8-14(9-7-12)15(18)17-11-13-4-2-1-3-5-13/h1-9H,10-11,16H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408793
(CHEMBL148986)Show InChI InChI=1S/C9H11NO2/c1-12-9(11)8-4-2-7(6-10)3-5-8/h2-5H,6,10H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| PubMed
| 4.34E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408790
(CHEMBL328875)Show InChI InChI=1S/C8H9NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,5,9H2,(H,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| PubMed
| 5.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408778
(CHEMBL147339)Show InChI InChI=1S/C11H15NO2/c1-2-7-14-11(13)10-5-3-9(8-12)4-6-10/h3-6H,2,7-8,12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408781
(CHEMBL355985)Show InChI InChI=1S/C17H19NO2/c18-13-15-8-10-16(11-9-15)17(19)20-12-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-11H,4,7,12-13,18H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408786
(CHEMBL148476)Show InChI InChI=1S/C7H10N2/c8-5-6-1-3-7(9)4-2-6/h1-4H,5,8-9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
| PubMed
| 5.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description The compound was tested for inhibition of the proteolytic enzyme trypsin. |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408791
(CHEMBL148656)Show InChI InChI=1S/C16H17NO2/c17-12-14-6-8-15(9-7-14)16(18)19-11-10-13-4-2-1-3-5-13/h1-9H,10-12,17H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 6.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408785
(CHEMBL273483)Show InChI InChI=1S/C8H11N/c1-7-2-4-8(6-9)5-3-7/h2-5H,6,9H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PubMed
| 6.66E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description The compound was tested for inhibition of the proteolytic enzyme trypsin. |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408780
(CHEMBL146872)Show InChI InChI=1S/C13H19NO2/c1-2-3-4-9-16-13(15)12-7-5-11(10-14)6-8-12/h5-8H,2-4,9-10,14H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50325562
(1-(4-CHLOROPHENYL)METHANAMINE | 4-Chloro-benzylami...)Show InChI InChI=1S/C7H8ClN/c8-7-3-1-6(5-9)2-4-7/h1-4H,5,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
| PubMed
| 7.00E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description The compound was tested for inhibition of the proteolytic enzyme trypsin. |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408792
(CHEMBL147525)Show InChI InChI=1S/C12H17NO2/c1-2-3-8-15-12(14)11-6-4-10(9-13)5-7-11/h4-7H,2-3,8-9,13H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9.09E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |
Serine protease 1
(Homo sapiens (Human)) | BDBM50408784
(CHEMBL12720 | Integrase inhibitor, R1{3})Show InChI InChI=1S/C8H11NO/c1-10-8-4-2-7(6-9)3-5-8/h2-5H,6,9H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Similars
| PubMed
| 1.00E+9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of trypsin |
J Med Chem 42: 5169-80 (2000)
BindingDB Entry DOI: 10.7270/Q2930VD5 |
More data for this Ligand-Target Pair | |