Affinity Data by PubMed id=10636248

PubMed code 10636248

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50073922 (CHEMBL86313 \| {(S)-1-[(7-Bromo-2,3-dioxo-1,2,3,4-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Zurich Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...				Bioorg Med Chem Lett 10: 75-8 (2000) BindingDB Entry DOI: 10.7270/Q2M907WV
University Hospital Zurich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50084064 (CHEMBL167952 \| {(S)-1-[(7-Chloro-2,3-dioxo-1,2,3,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Zurich Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...				Bioorg Med Chem Lett 10: 75-8 (2000) BindingDB Entry DOI: 10.7270/Q2M907WV
University Hospital Zurich Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50073930 (CHEMBL82963 \| {(S)-1-[(2,3-Dioxo-7-trifluoromethyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Zurich Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...				Bioorg Med Chem Lett 10: 75-8 (2000) BindingDB Entry DOI: 10.7270/Q2M907WV
University Hospital Zurich Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50084062 (CHEMBL354295 \| {(S)-1-[(7-Iodo-2,3-dioxo-1,2,3,4-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Zurich Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...				Bioorg Med Chem Lett 10: 75-8 (2000) BindingDB Entry DOI: 10.7270/Q2M907WV
University Hospital Zurich Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50084063 (CHEMBL162675 \| {(S)-1-[(7-Fluoro-2,3-dioxo-1,2,3,4...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Zurich Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...				Bioorg Med Chem Lett 10: 75-8 (2000) BindingDB Entry DOI: 10.7270/Q2M907WV
University Hospital Zurich Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50073950 (CHEMBL82626 \| {(S)-1-[(7-Nitro-2,3-dioxo-1,2,3,4-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Zurich Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...				Bioorg Med Chem Lett 10: 75-8 (2000) BindingDB Entry DOI: 10.7270/Q2M907WV
University Hospital Zurich Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50084065 (CHEMBL164231 \| {(S)-1-[(7-Cyano-2,3-dioxo-1,2,3,4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Zurich Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity for the glycine binding site on N-methyl-D-aspartate glutamate receptor by using [3H]-MDL-105,519 bin...				Bioorg Med Chem Lett 10: 75-8 (2000) BindingDB Entry DOI: 10.7270/Q2M907WV
University Hospital Zurich Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%