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PubMed code 10639276

Compile data set for download or QSAR
Found 6 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2Y purinoceptor 1


(Meleagris gallopavo)		BDBM50422300
PNG
(CHEMBL2364563)
Show SMILES CCCCNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C14H25N6O13P3/c1-2-3-4-16-14-19-8-11(15)17-6-18-12(8)20(14)13-10(22)9(21)7(31-13)5-30-35(26,27)33-36(28,29)32-34(23,24)25/h6-7,9-10,13,21-22H,2-5H2,1H3,(H,16,19)(H,26,27)(H,28,29)(H2,15,17,18)(H2,23,24,25)/p-4/t7-,9-,10-,13-/m1/s1
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n/an/an/an/a 5.10E+4n/an/an/an/a



Bar-Ilan University

Curated by ChEMBL


Assay Description
Compounds was tested for its ability to stimulate phospholipase C activity at the P2Y purinoceptor 1 in turkey erythrocyte membranes.

J Med Chem 42: 5325-37 (2000)


BindingDB Entry DOI: 10.7270/Q2V988S4
More data for this
Ligand-Target Pair
P2Y purinoceptor 1


(Meleagris gallopavo)		BDBM50422302
PNG
(CHEMBL2364568)
Show SMILES CCCCNc1nc(N)c2ncn([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)c2n1 |r|
Show InChI InChI=1S/C14H25N6O13P3/c1-2-3-4-16-14-18-11(15)8-12(19-14)20(6-17-8)13-10(22)9(21)7(31-13)5-30-35(26,27)33-36(28,29)32-34(23,24)25/h6-7,9-10,13,21-22H,2-5H2,1H3,(H,26,27)(H,28,29)(H2,23,24,25)(H3,15,16,18,19)/p-4/t7-,9-,10-,13-/m1/s1
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n/an/an/an/a 39n/an/an/an/a



Bar-Ilan University

Curated by ChEMBL


Assay Description
Compounds was tested for its ability to stimulate phospholipase C activity at the P2Y purinoceptor 1 in turkey erythrocyte membranes.

J Med Chem 42: 5325-37 (2000)


BindingDB Entry DOI: 10.7270/Q2V988S4
More data for this
Ligand-Target Pair
P2Y purinoceptor 1


(Meleagris gallopavo)		BDBM50422304
PNG
(CHEMBL2364567)
Show SMILES CCCCSc1nc(N)c2ncn([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)c2n1 |r|
Show InChI InChI=1S/C14H24N5O13P3S/c1-2-3-4-36-14-17-11(15)8-12(18-14)19(6-16-8)13-10(21)9(20)7(30-13)5-29-34(25,26)32-35(27,28)31-33(22,23)24/h6-7,9-10,13,20-21H,2-5H2,1H3,(H,25,26)(H,27,28)(H2,15,17,18)(H2,22,23,24)/p-4/t7-,9-,10-,13-/m1/s1
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n/an/an/an/a 18n/an/an/an/a



Bar-Ilan University

Curated by ChEMBL


Assay Description
Compounds was tested for its ability to stimulate phospholipase C activity at the P2Y purinoceptor 1 in turkey erythrocyte membranes.

J Med Chem 42: 5325-37 (2000)


BindingDB Entry DOI: 10.7270/Q2V988S4
More data for this
Ligand-Target Pair
P2Y purinoceptor 1


(Meleagris gallopavo)		BDBM50422299
PNG
(CHEMBL2364566)
Show SMILES CCCCOc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C14H24N5O14P3/c1-2-3-4-29-14-18-8-11(15)16-6-17-12(8)19(14)13-10(21)9(20)7(31-13)5-30-35(25,26)33-36(27,28)32-34(22,23)24/h6-7,9-10,13,20-21H,2-5H2,1H3,(H,25,26)(H,27,28)(H2,15,16,17)(H2,22,23,24)/p-4/t7-,9-,10-,13-/m1/s1
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n/an/an/an/a 5.71E+3n/an/an/an/a



Bar-Ilan University

Curated by ChEMBL


Assay Description
Compounds was tested for its ability to stimulate phospholipase C activity at the P2Y purinoceptor 1 in turkey erythrocyte membranes.

J Med Chem 42: 5325-37 (2000)


BindingDB Entry DOI: 10.7270/Q2V988S4
More data for this
Ligand-Target Pair
P2Y purinoceptor 1


(Meleagris gallopavo)		BDBM50422301
PNG
(CHEMBL2364565)
Show SMILES CCCCOc1nc(N)c2ncn([C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]3O)c2n1 |r|
Show InChI InChI=1S/C14H24N5O14P3/c1-2-3-4-29-14-17-11(15)8-12(18-14)19(6-16-8)13-10(21)9(20)7(31-13)5-30-35(25,26)33-36(27,28)32-34(22,23)24/h6-7,9-10,13,20-21H,2-5H2,1H3,(H,25,26)(H,27,28)(H2,15,17,18)(H2,22,23,24)/p-4/t7-,9-,10-,13-/m1/s1
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n/an/an/an/a 88n/an/an/an/a



Bar-Ilan University

Curated by ChEMBL


Assay Description
Compounds was tested for its ability to stimulate phospholipase C activity at the P2Y purinoceptor 1 in turkey erythrocyte membranes.

J Med Chem 42: 5325-37 (2000)


BindingDB Entry DOI: 10.7270/Q2V988S4
More data for this
Ligand-Target Pair
P2Y purinoceptor 1


(Meleagris gallopavo)		BDBM50422303
PNG
(CHEMBL2364564)
Show SMILES CCCCSc1nc2c(N)ncnc2n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C14H24N5O13P3S/c1-2-3-4-36-14-18-8-11(15)16-6-17-12(8)19(14)13-10(21)9(20)7(30-13)5-29-34(25,26)32-35(27,28)31-33(22,23)24/h6-7,9-10,13,20-21H,2-5H2,1H3,(H,25,26)(H,27,28)(H2,15,16,17)(H2,22,23,24)/p-4/t7-,9-,10-,13-/m1/s1
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n/an/an/an/a 1.00E+4n/an/an/an/a



Bar-Ilan University

Curated by ChEMBL


Assay Description
Compounds was tested for its ability to stimulate phospholipase C activity at the P2Y purinoceptor 1 in turkey erythrocyte membranes.

J Med Chem 42: 5325-37 (2000)


BindingDB Entry DOI: 10.7270/Q2V988S4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%