Affinity Data by PubMed id=10743951

PubMed code 10743951

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (CALF)	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 of calf cortex using [3H]U-69593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (CALF)	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 of calf cortex using [3H]U-69593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (CALF)	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 of calf cortex using [3H]U-69593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 of calf cortex using [3H]U-69593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 of calf cortex using [3H]U-69593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 of calf cortex using [3H]-U-69,593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 of calf cortex using [3H]-U-69,593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 of calf cortex using [3H]-U-69,593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50086682 ((+)-18-Methoxycoronaridine hydrochloride \| (+/-)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 of calf cortex using [3H]-U-69,593 as radioligand				Bioorg Med Chem Lett 10: 473-6 (2000) BindingDB Entry DOI: 10.7270/Q28W3DTX
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%