Affinity Data by PubMed id=10843230

PubMed code 10843230

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D1-like receptor in homogenate of caudateputamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50088753 (5-(3-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetra...) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc(Br)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D1-like receptor in homogenate of caudateputamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50088754 (CHEMBL274577 \| Cyclopentadienyltricarbonylrheniumb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D1-like receptor in homogenate of caudateputamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50088755 (5-(2-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetra...) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1Br Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D1-like receptor in homogenate of caudateputamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50088753 (5-(3-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetra...) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc(Br)c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2C receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50088756 (CHEMBL427996 \| Cyclopentadienyltricarbonylrheniumb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D1-like receptor in homogenate of caudateputamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50088753 (5-(3-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetra...) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc(Br)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2A receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2A receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50088755 (5-(2-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetra...) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1Br Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2C receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2C receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50088754 (CHEMBL274577 \| Cyclopentadienyltricarbonylrheniumb...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2A receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50088755 (5-(2-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetra...) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1Br Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2A receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50088754 (CHEMBL274577 \| Cyclopentadienyltricarbonylrheniumb...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2C receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50088756 (CHEMBL427996 \| Cyclopentadienyltricarbonylrheniumb...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2C receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50088756 (CHEMBL427996 \| Cyclopentadienyltricarbonylrheniumb...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	227	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards cerebral 5-hydroxytryptamine 2A receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM50088754 (CHEMBL274577 \| Cyclopentadienyltricarbonylrheniumb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	549	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D2-like receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM50088755 (5-(2-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetra...) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1Br Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	583	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D2-like receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM50088753 (5-(3-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetra...) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc(Br)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D2-like receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D2-like receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM50088756 (CHEMBL427996 \| Cyclopentadienyltricarbonylrheniumb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Compound was evaluated for affinity towards dopamine D2-like receptor in homogenate of caudate putamen tissue from rat brain				Bioorg Med Chem Lett 10: 1113-5 (2000) BindingDB Entry DOI: 10.7270/Q21N81NF
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%