Affinity Data by PubMed id=10866399

PubMed code 10866399

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089149 (2-Benzyl-9-phenyl-2,3,4,4a-tetrahydro-1H-indeno[2,...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089150 (2-Ethyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089148 (((3R,4S)-1-Ethyl-4-hydroxy-4-phenyl-piperidin-3-yl...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089146 (((3R,4S)-4-Hydroxy-1-methyl-4-phenyl-piperidin-3-y...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089144 (2-Methyl-9-phenyl-2,3,4,4a-tetrahydro-1H-indeno[2,...) Show SMILES CN1CCC2C(C1)=C(c1ccccc21)c1ccccc1 \|c:7\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM22567 (3H]pyrilamine \| CHEMBL511 \| Dorantamin \| Mepyramin...) Show SMILES COc1ccc(CN(CCN(C)C)c2ccccn2)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089147 (2-Methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1...) Show SMILES CN1CCC2=C(C1)C(c1ccccc21)c1ccccc1 \|c:4\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089151 (9-Phenyl-2,3-dihydro-1H-indeno[2,1-c]pyridine \| CH...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089152 (2-Methyl-9-phenyl-2,3-dihydro-1H-indeno[2,1-c]pyri...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50089145 (2-Benzyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description In vitro antagonistic activity at the Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 10: 1277-9 (2000) BindingDB Entry DOI: 10.7270/Q2T152VB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%