Affinity Data by PubMed id=11052787

PubMed code 11052787

Found 24 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Substance-P receptor (Homo sapiens (Human))	BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against H197A mutant NK1 receptor using [125]SP radioligand in COS cells.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against H265A mutant NK1 receptor using [125]SP radioligand in COS cells.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against human wild type NK1 receptor expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50001450 ((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Q165A mutant NK1 receptor expressed in CHO cells, using [125]SP as radioligand				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50409025 (CHEMBL2112246) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 2 expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50369642 (CHEMBL1790897) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 1				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50369645 (CHEMBL1790894) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 1 expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50409026 (CHEMBL2112245) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 2 expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50369646 (CHEMBL1790896) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against human somatostatin receptor subtype 4 (hSSTR4)				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50051567 (5-{(2R,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-6-[2-(1H-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 1				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50409025 (CHEMBL2112246) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 1 expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50409025 (CHEMBL2112246) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against human wild type NK1 receptor expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50409026 (CHEMBL2112245) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 1 expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50409026 (CHEMBL2112245) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against human wild type NK1 receptor expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50369645 (CHEMBL1790894) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 2 expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50369644 (CHEMBL1790895) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Tachykinin receptor 2 expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50409026 (CHEMBL2112245) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against H197A mutant NK1 receptor using [125]SP radioligand in COS cells.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50409025 (CHEMBL2112246) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against H197A mutant NK1 receptor using [125]SP radioligand in COS cells.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50369645 (CHEMBL1790894) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against human wild type NK1 receptor expressed in CHO cells, using [125]SP as radioligand.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50369645 (CHEMBL1790894) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against H197A mutant NK1 receptor using [125]SP radioligand in COS cells.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50369645 (CHEMBL1790894) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against Q165A mutant NK1 receptor expressed in CHO cells, using [125]SP as radioligand				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50409025 (CHEMBL2112246) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against H265A mutant NK1 receptor using [125]SP radioligand in COS cells.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50369645 (CHEMBL1790894) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against H265A mutant NK1 receptor using [125]SP radioligand in COS cells.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Substance-P receptor (Homo sapiens (Human))	BDBM50409026 (CHEMBL2112245) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against H265A mutant NK1 receptor using [125]SP radioligand in COS cells.				J Med Chem 43: 3827-31 (2000) BindingDB Entry DOI: 10.7270/Q2WS8TXP
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%