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PubMed code 11150171

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4


(Rattus norvegicus (Rat))
BDBM50095649
PNG
((2E)-1-[(5-azido-6-chloropyridin-3-yl)methyl]-N-ni...)
Show SMILES [O-][N+](=O)N=C1NCCN1Cc1cnc(Cl)c(c1)N=[N+]=[N-] |w:3.2|
Show InChI InChI=1S/C9H9ClN8O2/c10-8-7(14-16-11)3-6(4-13-8)5-17-2-1-12-9(17)15-18(19)20/h3-4H,1-2,5H2,(H,12,15)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
4.40n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-nicotine in rat alpha4 beta2 membranes


J Med Chem 43: 5003-9 (2001)


BindingDB Entry DOI: 10.7270/Q2NC60FD
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4


(Rattus norvegicus (Rat))
BDBM50212288
PNG
((2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimida...)
Show SMILES [O-][N+](=O)NC1=NCCN1Cc1ccc(Cl)nc1 |t:4|
Show InChI InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
50n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Binding affinity for nAChR with [3H]-nicotine in rat alpha4 beta2 membranes


J Med Chem 43: 5003-9 (2001)


BindingDB Entry DOI: 10.7270/Q2NC60FD
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%