Affinity Data by PubMed id=11206461

PubMed code 11206461

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2898 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50096419 (6-Chloro-4-cyclopropylethynyl-5-hydroxy-4-trifluor...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50096417 (6-Chloro-4-cyclopropylethynyl-5-methoxy-4-trifluor...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50096420 (7-Chloro-5-cyclopropyl-3a-trifluoromethyl-3,3a-dih...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50096418 (7-Chloro-5-pyridin-3-yl-3a-trifluoromethyl-3,3a-di...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50096421 (6-Chloro-5-methoxy-4-pyridin-3-ylethynyl-4-trifluo...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50096416 (6-Chloro-5-methoxy-4-phenylethynyl-4-trifluorometh...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50096414 (6-Chloro-5-hydroxy-4-phenylethynyl-4-trifluorometh...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50096415 (7-Chloro-5-phenyl-3a-trifluoromethyl-3,3a-dihydro-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	244	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Tested for inhibitory concentration against HIV-1 non-nucleoside reverse transcriptase				Bioorg Med Chem Lett 11: 211-4 (2001) BindingDB Entry DOI: 10.7270/Q2319WDF
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%