Affinity Data by PubMed id=11277522

PubMed code 11277522

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50097891 (4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...) Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT-as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50094674 (CHEMBL142862 \| [2-(4-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT-as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT-as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50094674 (CHEMBL142862 \| [2-(4-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards rat 5-hydroxytryptamine 2C receptor was determined using [125I]- DOI as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50094674 (CHEMBL142862 \| [2-(4-Fluoro-5-methoxy-1H-indol-3-y...) Show SMILES COc1ccc2[nH]cc(CCN(C)C)c2c1F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards rat 5-hydroxytryptamine 2A receptor was determined using [125I]- DOI as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50097891 (4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...) Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards rat 5-hydroxytryptamine 2A receptor was determined using [125I]- DOI as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50097891 (4-Fluoro-5-methoxy-3-(2-pyrrolidin-1-yl-ethyl)-1H-...) Show SMILES COc1ccc2[nH]cc(CCN3CCCC3)c2c1F Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinitty towards rat 5-hydroxytryptamine 2C receptor was determined using [125I]- DOI as radioligand				Bioorg Med Chem Lett 11: 793-5 (2001) BindingDB Entry DOI: 10.7270/Q2ZC824R
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%