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PubMed code 11300879

Compile data set for download or QSAR
Found 77 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50039026
PNG
(4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(O)c1
Show InChI InChI=1S/C27H37N3O2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26-/m1/s1
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 0.910n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50039029
PNG
((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 |r|
Show InChI InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1
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 1.57n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098462
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-hydroxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(O)c1
Show InChI InChI=1S/C26H35N3O2/c1-5-16-27-17-15-25(20(4)19-27)29(23-9-8-10-24(30)18-23)22-13-11-21(12-14-22)26(31)28(6-2)7-3/h5,8-14,18,20,25,30H,1,6-7,15-17,19H2,2-4H3/t20-,25+/m0/s1
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 1.85n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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 5.58n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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 5.58n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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 11.9n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098465
PNG
(CHEMBL353745 | N,N-Diethyl-4-{[3-methyl-1-(3-methy...)
Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-[#6])-c1ccccc1
Show InChI InChI=1S/C28H39N3O/c1-6-30(7-2)28(32)24-13-15-26(16-14-24)31(25-11-9-8-10-12-25)27-18-20-29(21-23(27)5)19-17-22(3)4/h8-17,23,27H,6-7,18-21H2,1-5H3/t23-,27+/m0/s1
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 15n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 18.8n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098451
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-4-29(5-2)27(31)23-13-15-25(16-14-23)30(24-9-7-6-8-10-24)26-17-18-28(19-21(26)3)20-22-11-12-22/h6-10,13-16,21-22,26H,4-5,11-12,17-20H2,1-3H3/t21-,26+/m0/s1
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 20n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098447
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-methoxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C27H37N3O2/c1-6-17-28-18-16-26(21(4)20-28)30(24-10-9-11-25(19-24)32-5)23-14-12-22(13-15-23)27(31)29(7-2)8-3/h6,9-15,19,21,26H,1,7-8,16-18,20H2,2-5H3/t21-,26+/m0/s1
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 22n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098468
PNG
(CHEMBL176806 | N,N-Diethyl-4-{[3-methyl-1-(2-methy...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC(C)=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-29(7-2)27(31)23-13-15-25(16-14-23)30(24-11-9-8-10-12-24)26-17-18-28(19-21(3)4)20-22(26)5/h8-16,22,26H,3,6-7,17-20H2,1-2,4-5H3/t22-,26+/m0/s1
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 36n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50039026
PNG
(4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(O)c1
Show InChI InChI=1S/C27H37N3O2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26-/m1/s1
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 36n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098458
PNG
(CHEMBL177610 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-[#6])-c1cccc(-[#8]-[#6])c1
Show InChI InChI=1S/C29H41N3O2/c1-7-31(8-2)29(33)24-12-14-25(15-13-24)32(26-10-9-11-27(20-26)34-6)28-17-19-30(21-23(28)5)18-16-22(3)4/h9-16,20,23,28H,7-8,17-19,21H2,1-6H3/t23-,28+/m0/s1
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 36n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098455
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-5-30(6-2)28(32)23-12-14-24(15-13-23)31(25-8-7-9-26(18-25)33-4)27-16-17-29(19-21(27)3)20-22-10-11-22/h7-9,12-15,18,21-22,27H,5-6,10-11,16-17,19-20H2,1-4H3/t21-,27+/m0/s1
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 36n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098457
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-phenyl-amino]-N,N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C24H33N3O/c1-5-26(6-2)24(28)20-12-14-22(15-13-20)27(21-10-8-7-9-11-21)23-16-17-25(4)18-19(23)3/h7-15,19,23H,5-6,16-18H2,1-4H3/t19-,23+/m0/s1
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 45.6n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 53n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098466
PNG
(CHEMBL175511 | N,N-Diethyl-4-{[3-methyl-1-(3-pheny...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C\C=C\c2ccccc2)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-4-34(5-2)32(36)28-18-20-30(21-19-28)35(29-16-10-7-11-17-29)31-22-24-33(25-26(31)3)23-12-15-27-13-8-6-9-14-27/h6-21,26,31H,4-5,22-25H2,1-3H3/b15-12+/t26-,31+/m0/s1
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 68n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098459
PNG
(CHEMBL434685 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC(C)=C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-7-30(8-2)28(32)23-12-14-24(15-13-23)31(25-10-9-11-26(18-25)33-6)27-16-17-29(19-21(3)4)20-22(27)5/h9-15,18,22,27H,3,7-8,16-17,19-20H2,1-2,4-6H3/t22-,27+/m0/s1
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 72n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098462
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-hydroxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(O)c1
Show InChI InChI=1S/C26H35N3O2/c1-5-16-27-17-15-25(20(4)19-27)29(23-9-8-10-24(30)18-23)22-13-11-21(12-14-22)26(31)28(6-2)7-3/h5,8-14,18,20,25,30H,1,6-7,15-17,19H2,2-4H3/t20-,25+/m0/s1
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 76.7n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 93n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098461
PNG
(CHEMBL355580 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C\C=C\c2ccccc2)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C33H41N3O2/c1-5-35(6-2)33(37)28-17-19-29(20-18-28)36(30-15-10-16-31(24-30)38-4)32-21-23-34(25-26(32)3)22-11-14-27-12-8-7-9-13-27/h7-20,24,26,32H,5-6,21-23,25H2,1-4H3/b14-11+/t26-,32+/m0/s1
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 93n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098462
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-hydroxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(O)c1
Show InChI InChI=1S/C26H35N3O2/c1-5-16-27-17-15-25(20(4)19-27)29(23-9-8-10-24(30)18-23)22-13-11-21(12-14-22)26(31)28(6-2)7-3/h5,8-14,18,20,25,30H,1,6-7,15-17,19H2,2-4H3/t20-,25+/m0/s1
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 126n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098454
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25-/m1/s1
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 126n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098448
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-(3-methoxy-phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C25H35N3O2/c1-6-27(7-2)25(29)20-11-13-21(14-12-20)28(22-9-8-10-23(17-22)30-5)24-15-16-26(4)18-19(24)3/h8-14,17,19,24H,6-7,15-16,18H2,1-5H3/t19-,24?/m0/s1
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 141n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098451
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-4-29(5-2)27(31)23-13-15-25(16-14-23)30(24-9-7-6-8-10-24)26-17-18-28(19-21(26)3)20-22-11-12-22/h6-10,13-16,21-22,26H,4-5,11-12,17-20H2,1-3H3/t21-,26+/m0/s1
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 160n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 171n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098448
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-(3-methoxy-phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C25H35N3O2/c1-6-27(7-2)25(29)20-11-13-21(14-12-20)28(22-9-8-10-23(17-22)30-5)24-15-16-26(4)18-19(24)3/h8-14,17,19,24H,6-7,15-16,18H2,1-5H3/t19-,24?/m0/s1
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 178n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098464
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-4-29(5-2)27(31)23-13-15-25(16-14-23)30(24-9-7-6-8-10-24)26-17-18-28(19-21(26)3)20-22-11-12-22/h6-10,13-16,21-22,26H,4-5,11-12,17-20H2,1-3H3/t21-,26-/m1/s1
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 193n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098456
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-5-30(6-2)28(32)23-12-14-24(15-13-23)31(25-8-7-9-26(18-25)33-4)27-16-17-29(19-21(27)3)20-22-10-11-22/h7-9,12-15,18,21-22,27H,5-6,10-11,16-17,19-20H2,1-4H3/t21-,27-/m1/s1
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 230n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098452
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-phenyl-amino]-N,N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C24H33N3O/c1-5-26(6-2)24(28)20-12-14-22(15-13-20)27(21-10-8-7-9-11-21)23-16-17-25(4)18-19(23)3/h7-15,19,23H,5-6,16-18H2,1-4H3/t19-,23-/m1/s1
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 257n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Delta-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098453
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-methoxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C27H37N3O2/c1-6-17-28-18-16-26(21(4)20-28)30(24-10-9-11-25(19-24)32-5)23-14-12-22(13-15-23)27(31)29(7-2)8-3/h6,9-15,19,21,26H,1,7-8,16-18,20H2,2-5H3/t21-,26-/m1/s1
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 379n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [H]DADLE to the delta opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098457
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-phenyl-amino]-N,N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C24H33N3O/c1-5-26(6-2)24(28)20-12-14-22(15-13-20)27(21-10-8-7-9-11-21)23-16-17-25(4)18-19(23)3/h7-15,19,23H,5-6,16-18H2,1-4H3/t19-,23+/m0/s1
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 388n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 1.16E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098468
PNG
(CHEMBL176806 | N,N-Diethyl-4-{[3-methyl-1-(2-methy...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC(C)=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-29(7-2)27(31)23-13-15-25(16-14-23)30(24-11-9-8-10-12-24)26-17-18-28(19-21(3)4)20-22(26)5/h8-16,22,26H,3,6-7,17-20H2,1-2,4-5H3/t22-,26+/m0/s1
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 1.26E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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 1.44E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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 1.45E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098452
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-phenyl-amino]-N,N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C24H33N3O/c1-5-26(6-2)24(28)20-12-14-22(15-13-20)27(21-10-8-7-9-11-21)23-16-17-25(4)18-19(23)3/h7-15,19,23H,5-6,16-18H2,1-4H3/t19-,23-/m1/s1
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 1.51E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098454
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25-/m1/s1
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 1.59E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50039029
PNG
((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 |r|
Show InChI InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1
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 1.61E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098451
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-4-29(5-2)27(31)23-13-15-25(16-14-23)30(24-9-7-6-8-10-24)26-17-18-28(19-21(26)3)20-22-11-12-22/h6-10,13-16,21-22,26H,4-5,11-12,17-20H2,1-3H3/t21-,26+/m0/s1
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 2.38E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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 2.62E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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 2.62E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 2.90E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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 3.28E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098448
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-(3-methoxy-phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C25H35N3O2/c1-6-27(7-2)25(29)20-11-13-21(14-12-20)28(22-9-8-10-23(17-22)30-5)24-15-16-26(4)18-19(24)3/h8-14,17,19,24H,6-7,15-16,18H2,1-5H3/t19-,24?/m0/s1
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 3.32E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098458
PNG
(CHEMBL177610 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-[#6])-c1cccc(-[#8]-[#6])c1
Show InChI InChI=1S/C29H41N3O2/c1-7-31(8-2)29(33)24-12-14-25(15-13-24)32(26-10-9-11-27(20-26)34-6)28-17-19-30(21-23(28)5)18-16-22(3)4/h9-16,20,23,28H,7-8,17-19,21H2,1-6H3/t23-,28+/m0/s1
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 3.39E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50039029
PNG
((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 |r|
Show InChI InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1
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 3.54E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098465
PNG
(CHEMBL353745 | N,N-Diethyl-4-{[3-methyl-1-(3-methy...)
Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-[#6])-c1ccccc1
Show InChI InChI=1S/C28H39N3O/c1-6-30(7-2)28(32)24-13-15-26(16-14-24)31(25-11-9-8-10-12-25)27-18-20-29(21-23(27)5)19-17-22(3)4/h8-17,23,27H,6-7,18-21H2,1-5H3/t23-,27+/m0/s1
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 3.79E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 3.90E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50083637
PNG
(4-(((3S,4R)-1-allyl-3-methylpiperidin-4-yl)(phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m0/s1
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>4.85E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098453
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-methoxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C27H37N3O2/c1-6-17-28-18-16-26(21(4)20-28)30(24-10-9-11-25(19-24)32-5)23-14-12-22(13-15-23)27(31)29(7-2)8-3/h6,9-15,19,21,26H,1,7-8,16-18,20H2,2-5H3/t21-,26-/m1/s1
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 4.87E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098447
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-methoxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C27H37N3O2/c1-6-17-28-18-16-26(21(4)20-28)30(24-10-9-11-25(19-24)32-5)23-14-12-22(13-15-23)27(31)29(7-2)8-3/h6,9-15,19,21,26H,1,7-8,16-18,20H2,2-5H3/t21-,26+/m0/s1
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 5.33E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098464
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-4-29(5-2)27(31)23-13-15-25(16-14-23)30(24-9-7-6-8-10-24)26-17-18-28(19-21(26)3)20-22-11-12-22/h6-10,13-16,21-22,26H,4-5,11-12,17-20H2,1-3H3/t21-,26-/m1/s1
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 5.34E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098459
PNG
(CHEMBL434685 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC(C)=C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-7-30(8-2)28(32)23-12-14-24(15-13-23)31(25-10-9-11-26(18-25)33-6)27-16-17-29(19-21(3)4)20-22(27)5/h9-15,18,22,27H,3,7-8,16-17,19-20H2,1-2,4-6H3/t22-,27+/m0/s1
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 5.69E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098448
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-(3-methoxy-phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C25H35N3O2/c1-6-27(7-2)25(29)20-11-13-21(14-12-20)28(22-9-8-10-23(17-22)30-5)24-15-16-26(4)18-19(24)3/h8-14,17,19,24H,6-7,15-16,18H2,1-5H3/t19-,24?/m0/s1
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>5.92E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098458
PNG
(CHEMBL177610 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-[#6])-c1cccc(-[#8]-[#6])c1
Show InChI InChI=1S/C29H41N3O2/c1-7-31(8-2)29(33)24-12-14-25(15-13-24)32(26-10-9-11-27(20-26)34-6)28-17-19-30(21-23(28)5)18-16-22(3)4/h9-16,20,23,28H,7-8,17-19,21H2,1-6H3/t23-,28+/m0/s1
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 6.02E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098448
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-(3-methoxy-phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C25H35N3O2/c1-6-27(7-2)25(29)20-11-13-21(14-12-20)28(22-9-8-10-23(17-22)30-5)24-15-16-26(4)18-19(24)3/h8-14,17,19,24H,6-7,15-16,18H2,1-5H3/t19-,24?/m0/s1
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>6.06E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098464
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-p...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-4-29(5-2)27(31)23-13-15-25(16-14-23)30(24-9-7-6-8-10-24)26-17-18-28(19-21(26)3)20-22-11-12-22/h6-10,13-16,21-22,26H,4-5,11-12,17-20H2,1-3H3/t21-,26-/m1/s1
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>6.06E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098452
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-phenyl-amino]-N,N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C24H33N3O/c1-5-26(6-2)24(28)20-12-14-22(15-13-20)27(21-10-8-7-9-11-21)23-16-17-25(4)18-19(23)3/h7-15,19,23H,5-6,16-18H2,1-4H3/t19-,23-/m1/s1
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>6.06E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098457
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-phenyl-amino]-N,N...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C24H33N3O/c1-5-26(6-2)24(28)20-12-14-22(15-13-20)27(21-10-8-7-9-11-21)23-16-17-25(4)18-19(23)3/h7-15,19,23H,5-6,16-18H2,1-4H3/t19-,23+/m0/s1
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>6.06E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098448
PNG
(4-[(1,3-Dimethyl-piperidin-4-yl)-(3-methoxy-phenyl...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C25H35N3O2/c1-6-27(7-2)25(29)20-11-13-21(14-12-20)28(22-9-8-10-23(17-22)30-5)24-15-16-26(4)18-19(24)3/h8-14,17,19,24H,6-7,15-16,18H2,1-5H3/t19-,24?/m0/s1
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 6.30E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 6.32E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098466
PNG
(CHEMBL175511 | N,N-Diethyl-4-{[3-methyl-1-(3-pheny...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C\C=C\c2ccccc2)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-4-34(5-2)32(36)28-18-20-30(21-19-28)35(29-16-10-7-11-17-29)31-22-24-33(25-26(31)3)23-12-15-27-13-8-6-9-14-27/h6-21,26,31H,4-5,22-25H2,1-3H3/b15-12+/t26-,31+/m0/s1
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 6.43E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098456
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-5-30(6-2)28(32)23-12-14-24(15-13-23)31(25-8-7-9-26(18-25)33-4)27-16-17-29(19-21(27)3)20-22-10-11-22/h7-9,12-15,18,21-22,27H,5-6,10-11,16-17,19-20H2,1-4H3/t21-,27-/m1/s1
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>6.54E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098455
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-5-30(6-2)28(32)23-12-14-24(15-13-23)31(25-8-7-9-26(18-25)33-4)27-16-17-29(19-21(27)3)20-22-10-11-22/h7-9,12-15,18,21-22,27H,5-6,10-11,16-17,19-20H2,1-4H3/t21-,27+/m0/s1
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>6.54E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098461
PNG
(CHEMBL355580 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C\C=C\c2ccccc2)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C33H41N3O2/c1-5-35(6-2)33(37)28-17-19-29(20-18-28)36(30-15-10-16-31(24-30)38-4)32-21-23-34(25-26(32)3)22-11-14-27-12-8-7-9-13-27/h7-20,24,26,32H,5-6,21-23,25H2,1-4H3/b14-11+/t26-,32+/m0/s1
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>6.54E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098447
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-methoxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C27H37N3O2/c1-6-17-28-18-16-26(21(4)20-28)30(24-10-9-11-25(19-24)32-5)23-14-12-22(13-15-23)27(31)29(7-2)8-3/h6,9-15,19,21,26H,1,7-8,16-18,20H2,2-5H3/t21-,26+/m0/s1
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>7.46E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098468
PNG
(CHEMBL176806 | N,N-Diethyl-4-{[3-methyl-1-(2-methy...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC(C)=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-29(7-2)27(31)23-13-15-25(16-14-23)30(24-11-9-8-10-12-24)26-17-18-28(19-21(3)4)20-22(26)5/h8-16,22,26H,3,6-7,17-20H2,1-2,4-5H3/t22-,26+/m0/s1
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>7.46E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098453
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-(3-methoxy-ph...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C27H37N3O2/c1-6-17-28-18-16-26(21(4)20-28)30(24-10-9-11-25(19-24)32-5)23-14-12-22(13-15-23)27(31)29(7-2)8-3/h6,9-15,19,21,26H,1,7-8,16-18,20H2,2-5H3/t21-,26-/m1/s1
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>7.46E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098461
PNG
(CHEMBL355580 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C\C=C\c2ccccc2)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C33H41N3O2/c1-5-35(6-2)33(37)28-17-19-29(20-18-28)36(30-15-10-16-31(24-30)38-4)32-21-23-34(25-26(32)3)22-11-14-27-12-8-7-9-13-27/h7-20,24,26,32H,5-6,21-23,25H2,1-4H3/b14-11+/t26-,32+/m0/s1
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>7.46E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098455
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-5-30(6-2)28(32)23-12-14-24(15-13-23)31(25-8-7-9-26(18-25)33-4)27-16-17-29(19-21(27)3)20-22-10-11-22/h7-9,12-15,18,21-22,27H,5-6,10-11,16-17,19-20H2,1-4H3/t21-,27+/m0/s1
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>7.46E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098465
PNG
(CHEMBL353745 | N,N-Diethyl-4-{[3-methyl-1-(3-methy...)
Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6@@H]-1-[#6])-c1ccccc1
Show InChI InChI=1S/C28H39N3O/c1-6-30(7-2)28(32)24-13-15-26(16-14-24)31(25-11-9-8-10-12-25)27-18-20-29(21-23(27)5)19-17-22(3)4/h8-17,23,27H,6-7,18-21H2,1-5H3/t23-,27+/m0/s1
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>7.46E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098456
PNG
(4-[(1-Cyclopropylmethyl-3-methyl-piperidin-4-yl)-(...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC2CC2)C[C@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-5-30(6-2)28(32)23-12-14-24(15-13-23)31(25-8-7-9-26(18-25)33-4)27-16-17-29(19-21(27)3)20-22-10-11-22/h7-9,12-15,18,21-22,27H,5-6,10-11,16-17,19-20H2,1-4H3/t21-,27-/m1/s1
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>7.46E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098459
PNG
(CHEMBL434685 | N,N-Diethyl-4-{(3-methoxy-phenyl)-[...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC(C)=C)C[C@@H]1C)c1cccc(OC)c1
Show InChI InChI=1S/C28H39N3O2/c1-7-30(8-2)28(32)23-12-14-24(15-13-23)31(25-10-9-11-26(18-25)33-6)27-16-17-29(19-21(3)4)20-22(27)5/h9-15,18,22,27H,3,7-8,16-17,19-20H2,1-2,4-6H3/t22-,27+/m0/s1
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>7.46E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098454
PNG
(4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(CC=C)C[C@H]1C)c1ccccc1
Show InChI InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25-/m1/s1
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 8.70E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098446
PNG
(4-[(1-Allyl-2,5-dimethyl-piperidin-4-yl)-phenyl-am...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N(C1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C27H37N3O/c1-6-18-29-20-21(4)26(19-22(29)5)30(24-12-10-9-11-13-24)25-16-14-23(15-17-25)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m0/s1
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 9.91E+3n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]DAMGO to the mu opioid receptor from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
Kappa-type opioid receptor


(Rattus norvegicus (rat))		BDBM50098466
PNG
(CHEMBL175511 | N,N-Diethyl-4-{[3-methyl-1-(3-pheny...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1CCN(C\C=C\c2ccccc2)C[C@@H]1C)c1ccccc1
Show InChI InChI=1S/C32H39N3O/c1-4-34(5-2)32(36)28-18-20-30(21-19-28)35(29-16-10-7-11-17-29)31-22-24-33(25-26(31)3)23-12-15-27-13-8-6-9-14-27/h6-21,26,31H,4-5,22-25H2,1-3H3/b15-12+/t26-,31+/m0/s1
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 1.35E+4n/an/an/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Affinity of [3H]U-69593 to opioid receptor kappa 1 from rat brain

J Med Chem 44: 972-87 (2001)


BindingDB Entry DOI: 10.7270/Q2V69K8G
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%