Affinity Data by PubMed id=11327592

PubMed code 11327592

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50099016 (CHEMBL275964 \| Cyclohexanecarboxylic acid {(S)-1-b...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT from CHO cells stably transfected with human 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50099015 (CHEMBL10796 \| Cyclohexanecarboxylic acid {(R)-1-be...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT from CHO cells stably transfected with human 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50099011 (1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT from CHO cells stably transfected with human 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50099014 (CHEMBL10793 \| Cyclohexanecarboxylic acid {(R)-1-be...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT from CHO cells stably transfected with human 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50099013 (CHEMBL10603 \| N-{(R)-1-Benzyl-2-[4-(4-methoxy-[1,2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT from CHO cells stably transfected with human 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50099012 (CHEMBL10764 \| N-{(S)-1-Benzyl-2-[4-(4-chloro-[1,2,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	425	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Ability to displace [3H]-8-OH-DPAT from CHO cells stably transfected with human 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50099011 (1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-m...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	489	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Percent inhibition of the compound towards dopamine D3 receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50099011 (1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-m...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Percent inhibition of the compound towards dopamine D4 receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50099011 (1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-m...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Percent inhibition of the compound towards dopamine D2 receptor				Bioorg Med Chem Lett 11: 1069-71 (2001) BindingDB Entry DOI: 10.7270/Q2SJ1JWX
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%