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PubMed code 11378373

Compile data set for download or QSAR
Found 35 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100036
PNG
((S)-2-(2,4-Dimethyl-benzoylamino)-3-(4-nitro-pheny...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1ccc(C)cc1C
Show InChI InChI=1S/C20H22N2O5/c1-4-27-20(24)18(12-15-6-8-16(9-7-15)22(25)26)21-19(23)17-10-5-13(2)11-14(17)3/h5-11,18H,4,12H2,1-3H3,(H,21,23)/t18-/m0/s1
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n/an/a 3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a 5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity of the compound against C-C chemokine receptor type 3 by displacing Eotaxin radioligand,using [Ca2+] mobilization assay

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a 7n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity of the compound against C-C chemokine receptor type 3 by displacing Eotaxin-2 radioligand,using [Ca2+] mobilization assay

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100044
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H20N2O5/c1-2-29-22(26)20(14-15-10-12-17(13-11-15)24(27)28)23-21(25)19-9-5-7-16-6-3-4-8-18(16)19/h3-13,20H,2,14H2,1H3,(H,23,25)/t20-/m0/s1
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n/an/a 8n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100027
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C27H22N2O5/c30-26(24-12-6-10-21-9-4-5-11-23(21)24)28-25(17-19-13-15-22(16-14-19)29(32)33)27(31)34-18-20-7-2-1-3-8-20/h1-16,25H,17-18H2,(H,28,30)/t25-/m0/s1
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n/an/a 18n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100037
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES CC(C)OC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C23H22N2O5/c1-15(2)30-23(27)21(14-16-10-12-18(13-11-16)25(28)29)24-22(26)20-9-5-7-17-6-3-4-8-19(17)20/h3-13,15,21H,14H2,1-2H3,(H,24,26)/t21-/m0/s1
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n/an/a 21n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a 25n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity of the compound against C-C chemokine receptor type 3 by displacing Eotaxin radioligand,using Esonophil chemotaxis assay

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a 32n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity of the compound against C-C chemokine receptor type 3 by displacing Eotaxin radioligand,using Esonophil chemotaxis assay

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a 32n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity of the compound against C-C chemokine receptor type 3 by displacing Eotaxin radioligand,using Esonophil chemotaxis assay

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a 35n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity of the compound against C-C chemokine receptor type 3 by displacing Eotaxin radioligand,using Esonophil chemotaxis assay

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a 35n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a 38n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity of the compound against C-C chemokine receptor type 3 by displacing [125I]-MCP-4 radioligand,using CCR3 binding assay

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100041
PNG
((S)-2-Benzoylamino-3-(4-nitro-phenyl)-propionic ac...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1ccccc1
Show InChI InChI=1S/C18H18N2O5/c1-2-25-18(22)16(19-17(21)14-6-4-3-5-7-14)12-13-8-10-15(11-9-13)20(23)24/h3-11,16H,2,12H2,1H3,(H,19,21)/t16-/m0/s1
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n/an/a 49n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100039
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES CC(C)(C)OC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C24H24N2O5/c1-24(2,3)31-23(28)21(15-16-11-13-18(14-12-16)26(29)30)25-22(27)20-10-6-8-17-7-4-5-9-19(17)20/h4-14,21H,15H2,1-3H3,(H,25,27)/t21-/m0/s1
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n/an/a 57n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100025
PNG
((S)-3-(4-Hydroxy-phenyl)-2-[(naphthalene-1-carbony...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H21NO4/c1-2-27-22(26)20(14-15-10-12-17(24)13-11-15)23-21(25)19-9-5-7-16-6-3-4-8-18(16)19/h3-13,20,24H,2,14H2,1H3,(H,23,25)/t20-/m0/s1
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n/an/a 80n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100040
PNG
((S)-2-Benzoylamino-3-phenyl-propionic acid ethyl e...)
Show SMILES CCOC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
Show InChI InChI=1S/C18H19NO3/c1-2-22-18(21)16(13-14-9-5-3-6-10-14)19-17(20)15-11-7-4-8-12-15/h3-12,16H,2,13H2,1H3,(H,19,20)/t16-/m0/s1
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n/an/a 190n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100028
PNG
((S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic aci...)
Show SMILES CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1
Show InChI InChI=1S/C20H20N2O3/c1-2-25-20(24)18(22-19(23)14-8-4-3-5-9-14)12-15-13-21-17-11-7-6-10-16(15)17/h3-11,13,18,21H,2,12H2,1H3,(H,22,23)/t18-/m0/s1
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n/an/a 325n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100021
PNG
((S)-2-[(Naphthalene-1-carbonyl)-amino]-3-(4-nitro-...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C21H18N2O5/c1-28-21(25)19(13-14-9-11-16(12-10-14)23(26)27)22-20(24)18-8-4-6-15-5-2-3-7-17(15)18/h2-12,19H,13H2,1H3,(H,22,24)/t19-/m0/s1
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n/an/a>330n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity of the compound against C-C chemokine receptor type 3 by displacing MCP-4 radioligand,using Esonophil chemotaxis assay

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100038
PNG
((S)-2-Benzoylamino-3-(4-hydroxy-phenyl)-propionic ...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccccc1
Show InChI InChI=1S/C18H19NO4/c1-2-23-18(22)16(12-13-8-10-15(20)11-9-13)19-17(21)14-6-4-3-5-7-14/h3-11,16,20H,2,12H2,1H3,(H,19,21)/t16-/m0/s1
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n/an/a 383n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100033
PNG
((S)-2-Benzoylamino-3-(4-hydroxy-3,5-diiodo-phenyl)...)
Show SMILES CCOC(=O)[C@H](Cc1cc(I)c(O)c(I)c1)NC(=O)c1ccccc1
Show InChI InChI=1S/C18H17I2NO4/c1-2-25-18(24)15(21-17(23)12-6-4-3-5-7-12)10-11-8-13(19)16(22)14(20)9-11/h3-9,15,22H,2,10H2,1H3,(H,21,23)/t15-/m0/s1
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n/an/a 535n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100034
PNG
((S)-3-(4-Hydroxy-phenyl)-2-[(pyridine-2-carbonyl)-...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccccn1
Show InChI InChI=1S/C17H18N2O4/c1-2-23-17(22)15(11-12-6-8-13(20)9-7-12)19-16(21)14-5-3-4-10-18-14/h3-10,15,20H,2,11H2,1H3,(H,19,21)/t15-/m0/s1
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n/an/a 1.70E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100042
PNG
((S)-3-(4-Hydroxy-phenyl)-2-phenylacetylamino-propi...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Cc1ccccc1
Show InChI InChI=1S/C19H21NO4/c1-2-24-19(23)17(12-15-8-10-16(21)11-9-15)20-18(22)13-14-6-4-3-5-7-14/h3-11,17,21H,2,12-13H2,1H3,(H,20,22)/t17-/m0/s1
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n/an/a 2.60E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100019
PNG
(CHEMBL284577 | Naphthalene-1-carboxylic acid [(S)-...)
Show SMILES [O-][N+](=O)c1ccc(C[C@H](NC(=O)c2cccc3ccccc23)C(=O)NCc2ccccc2)cc1
Show InChI InChI=1S/C27H23N3O4/c31-26(24-12-6-10-21-9-4-5-11-23(21)24)29-25(17-19-13-15-22(16-14-19)30(33)34)27(32)28-18-20-7-2-1-3-8-20/h1-16,25H,17-18H2,(H,28,32)(H,29,31)/t25-/m0/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100026
PNG
((S)-2-Benzoylamino-4-phenyl-butyric acid ethyl est...)
Show SMILES CCOC(=O)[C@H](CCc1ccccc1)NC(=O)c1ccccc1
Show InChI InChI=1S/C19H21NO3/c1-2-23-19(22)17(14-13-15-9-5-3-6-10-15)20-18(21)16-11-7-4-8-12-16/h3-12,17H,2,13-14H2,1H3,(H,20,21)/t17-/m0/s1
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n/an/a 5.95E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100045
PNG
((S)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propi...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C28H30N2O6/c1-2-35-27(33)25(18-21-13-15-23(31)16-14-21)29-26(32)24(17-20-9-5-3-6-10-20)30-28(34)36-19-22-11-7-4-8-12-22/h3-16,24-25,31H,2,17-19H2,1H3,(H,29,32)(H,30,34)/t24-,25-/m0/s1
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n/an/a 6.25E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100043
PNG
((S)-2-Benzoylamino-propionic acid ethyl ester | CH...)
Show SMILES CCOC(=O)[C@H](C)NC(=O)c1ccccc1
Show InChI InChI=1S/C12H15NO3/c1-3-16-12(15)9(2)13-11(14)10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,14)/t9-/m0/s1
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n/an/a 9.00E+3n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100024
PNG
((S)-3-(4-Hydroxy-phenyl)-2-(toluene-4-sulfonylamin...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NS(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C18H21NO5S/c1-3-24-18(21)17(12-14-6-8-15(20)9-7-14)19-25(22,23)16-10-4-13(2)5-11-16/h4-11,17,19-20H,3,12H2,1-2H3/t17-/m0/s1
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n/an/a 1.60E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100030
PNG
((S)-Benzoylamino-phenyl-acetic acid ethyl ester | ...)
Show SMILES CCOC(=O)[C@@H](NC(=O)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C17H17NO3/c1-2-21-17(20)15(13-9-5-3-6-10-13)18-16(19)14-11-7-4-8-12-14/h3-12,15H,2H2,1H3,(H,18,19)/t15-/m0/s1
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n/an/a>2.00E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100032
PNG
((S)-2-((S)-2-Benzyloxycarbonylamino-4-carbamoyl-bu...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C24H29N3O7/c1-2-33-23(31)20(14-16-8-10-18(28)11-9-16)26-22(30)19(12-13-21(25)29)27-24(32)34-15-17-6-4-3-5-7-17/h3-11,19-20,28H,2,12-15H2,1H3,(H2,25,29)(H,26,30)(H,27,32)/t19-,20-/m0/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100020
PNG
((S)-2-((S)-2-Benzyloxycarbonylamino-3-hydroxy-prop...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C22H26N2O7/c1-2-30-21(28)18(12-15-8-10-17(26)11-9-15)23-20(27)19(13-25)24-22(29)31-14-16-6-4-3-5-7-16/h3-11,18-19,25-26H,2,12-14H2,1H3,(H,23,27)(H,24,29)/t18-,19-/m0/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100022
PNG
(2-((S)-2-Benzyloxycarbonylamino-3-carbamoyl-propio...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C23H27N3O7/c1-2-32-22(30)19(12-15-8-10-17(27)11-9-15)25-21(29)18(13-20(24)28)26-23(31)33-14-16-6-4-3-5-7-16/h3-11,18-19,27H,2,12-14H2,1H3,(H2,24,28)(H,25,29)(H,26,31)/t18-,19-/m0/s1
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n/an/a>2.50E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100031
PNG
(CHEMBL32784 | Naphthalene-1-carboxylic acid [(S)-1...)
Show SMILES CN(C)C(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C22H21N3O4/c1-24(2)22(27)20(14-15-10-12-17(13-11-15)25(28)29)23-21(26)19-9-5-7-16-6-3-4-8-18(16)19/h3-13,20H,14H2,1-2H3,(H,23,26)/t20-/m0/s1
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n/an/a 3.30E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100029
PNG
(CHEMBL32965 | Naphthalene-1-carboxylic acid [(S)-1...)
Show SMILES CCCC(=O)[C@H](Cc1ccc(cc1)[N+]([O-])=O)NC(=O)c1cccc2ccccc12
Show InChI InChI=1S/C23H22N2O4/c1-2-6-22(26)21(15-16-11-13-18(14-12-16)25(28)29)24-23(27)20-10-5-8-17-7-3-4-9-19(17)20/h3-5,7-14,21H,2,6,15H2,1H3,(H,24,27)/t21-/m0/s1
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n/an/a>3.30E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100023
PNG
((S)-3-(4-Hydroxy-phenyl)-2-(3-phenyl-ureido)-propi...)
Show SMILES CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Nc1ccccc1
Show InChI InChI=1S/C18H20N2O4/c1-2-24-17(22)16(12-13-8-10-15(21)11-9-13)20-18(23)19-14-6-4-3-5-7-14/h3-11,16,21H,2,12H2,1H3,(H2,19,20,23)/t16-/m0/s1
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n/an/a>3.30E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50100035
PNG
((R)-2-Benzoylamino-3-(4-hydroxy-phenyl)-propionic ...)
Show SMILES CCOC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)c1ccccc1
Show InChI InChI=1S/C18H19NO4/c1-2-23-18(22)16(12-13-8-10-15(20)11-9-13)19-17(21)14-6-4-3-5-7-14/h3-11,16,20H,2,12H2,1H3,(H,19,21)/t16-/m1/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibitory activity against human eosinophil C-C chemokine receptor type 3 using [125I]- human eotaxin as the radioligand

Bioorg Med Chem Lett 11: 1441-4 (2001)


BindingDB Entry DOI: 10.7270/Q27D2TD0
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%