Affinity Data by PubMed id=11708931

PubMed code 11708931

Found 44 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106700 (1-[6-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-hexyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50106693 ((5,6-Diphenyl-pyridazin-3-yl)-octyl-amine \| CHEMBL...) Show SMILES CCCCCCCCNc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Acyl-coenzyme A:cholesterol acyltransferase in macrophages				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50106685 (6-Heptyloxy-3,4-diphenyl-pyridazine \| CHEMBL422286) Show SMILES CCCCCCCOc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Acyl-coenzyme A:cholesterol acyltransferase in macrophages				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50106676 ((5,6-Diphenyl-pyridazin-3-yl)-nonyl-amine \| CHEMBL...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Acyl-coenzyme A:cholesterol acyltransferase in macrophages				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106676 ((5,6-Diphenyl-pyridazin-3-yl)-nonyl-amine \| CHEMBL...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106672 ((5,6-Diphenyl-pyridazin-3-yl)-hexyl-amine \| CHEMBL...) Show SMILES CCCCCCNc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106704 (6-(Octane-1-sulfonyl)-3,4-diphenyl-pyridazine \| CH...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106693 ((5,6-Diphenyl-pyridazin-3-yl)-octyl-amine \| CHEMBL...) Show SMILES CCCCCCCCNc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106701 (CHEMBL435980 \| Formic acid 5,5,6a,12b-tetramethyl-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106690 (6-(Heptane-1-sulfonyl)-3,4-diphenyl-pyridazine \| C...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106680 ((5,6-Diphenyl-pyridazin-3-yl)-heptyl-amine \| CHEMB...) Show SMILES CCCCCCCNc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106702 (2-Hexyl-4-methyl-5,6-diphenyl-2H-pyridazin-3-one \|...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106686 (2-Hexyl-5,6-diphenyl-2H-pyridazin-3-one \| CHEMBL13...) Show SMILES CCCCCCn1nc(-c2ccccc2)c(cc1=O)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106685 (6-Heptyloxy-3,4-diphenyl-pyridazine \| CHEMBL422286) Show SMILES CCCCCCCOc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106689 (6-(Hexane-1-sulfonyl)-3,4-diphenyl-pyridazine \| CH...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106703 (6-Hexylsulfanyl-3,4-diphenyl-pyridazine \| CHEMBL13...) Show SMILES CCCCCCSc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106678 (2-Pentyl-5,6-diphenyl-2H-pyridazin-3-one \| CHEMBL1...) Show SMILES CCCCCn1nc(-c2ccccc2)c(cc1=O)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106684 (6-Hexyloxy-3,4-diphenyl-pyridazine \| CHEMBL133095) Show SMILES CCCCCCOc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106706 (6-Pentyloxy-3,4-diphenyl-pyridazine \| CHEMBL345073) Show SMILES CCCCCOc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106709 (6-(Hexane-1-sulfinyl)-3,4-diphenyl-pyridazine \| CH...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106677 (6-Heptylsulfanyl-3,4-diphenyl-pyridazine \| CHEMBL1...) Show SMILES CCCCCCCSc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106688 (6-(Nonane-1-sulfonyl)-3,4-diphenyl-pyridazine \| CH...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106682 (6-(Heptane-1-sulfinyl)-3,4-diphenyl-pyridazine \| C...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106705 (2-Octyl-5,6-diphenyl-2H-pyridazin-3-one \| CHEMBL33...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106695 (2-Nonyl-5,6-diphenyl-2H-pyridazin-3-one \| CHEMBL33...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106681 (2-Heptyl-5,6-diphenyl-2H-pyridazin-3-one \| CHEMBL1...) Show SMILES CCCCCCCn1nc(-c2ccccc2)c(cc1=O)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106710 (6-(Nonane-1-sulfinyl)-3,4-diphenyl-pyridazine \| CH...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106692 (6-(Octane-1-sulfinyl)-3,4-diphenyl-pyridazine \| CH...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106697 (6-Octyloxy-3,4-diphenyl-pyridazine \| CHEMBL136099) Show SMILES CCCCCCCCOc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106694 (6-Nonylsulfanyl-3,4-diphenyl-pyridazine \| CHEMBL33...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106699 (2-Cyclopentyl-5,6-diphenyl-2H-pyridazin-3-one \| CH...) Show SMILES O=c1cc(-c2ccccc2)c(nn1C1CCCC1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106675 (6-Octylsulfanyl-3,4-diphenyl-pyridazine \| CHEMBL33...) Show SMILES CCCCCCCCSc1cc(-c2ccccc2)c(nn1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106708 (2-Isopropyl-5,6-diphenyl-2H-pyridazin-3-one \| CHEM...) Show SMILES CC(C)n1nc(-c2ccccc2)c(cc1=O)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.52E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106696 (2-Butyl-5,6-diphenyl-2H-pyridazin-3-one \| CHEMBL34...) Show SMILES CCCCn1nc(-c2ccccc2)c(cc1=O)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.76E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106707 (6-Nonyloxy-3,4-diphenyl-pyridazine \| CHEMBL137300) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106679 (5,6-Diphenyl-2-propyl-2H-pyridazin-3-one \| CHEMBL1...) Show SMILES CCCn1nc(-c2ccccc2)c(cc1=O)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106674 (7-(5,6-Diphenyl-pyridazin-3-ylsulfanyl)-heptanoic ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106687 (7-(6-Oxo-3,4-diphenyl-6H-pyridazin-1-yl)-heptanoic...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106683 (9-(5,6-Diphenyl-pyridazin-3-ylsulfanyl)-nonanoic a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106698 (2-Cyclohexyl-5,6-diphenyl-2H-pyridazin-3-one \| CHE...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106691 (CHEMBL337896 \| Hexanoic acid (5,6-diphenyl-pyridaz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50002953 (8-(5,6-Diphenyl-pyridazin-3-ylsulfanyl)-octanoic a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50002956 (8-(6-Oxo-3,4-diphenyl-6H-pyridazin-1-yl)-octanoic ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Rattus norvegicus)	BDBM50106673 (6-(5,6-Diphenyl-pyridazin-3-ylsulfanyl)-hexanoic a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Firenze Curated by ChEMBL					Assay Description In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes				J Med Chem 44: 4292-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VMS
Università di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%