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PubMed code 11909733

Compile data set for download or QSAR
Found 30 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (Human))
BDBM7533
PNG
((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)
Show SMILES CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1 |r|
Show InChI InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1
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n/an/a 800n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cell division cycle 2 (CDK1)-cyclin B


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (Human))
BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 5-p35nck5a


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (Human))
BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 2-cyclin A


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (Human))
BDBM5718
PNG
(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Show SMILES Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12
Show InChI InChI=1S/C15H18N6O/c1-21-10-18-12-13(17-9-11-5-3-2-4-6-11)19-15(16-7-8-22)20-14(12)21/h2-6,10,22H,7-9H2,1H3,(H2,16,17,19,20)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 5-p35nck5a


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3


(Homo sapiens (Human))
BDBM100152
PNG
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
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n/an/a 1.80E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cell division cycle 2 (CDK1)-cyclin B


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (Human))
BDBM100152
PNG
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
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n/an/a 2.10E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 5-p35nck5a


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (Human))
BDBM50111433
PNG
(1-(2-Chloro-5-nitro-phenyl)-9H-beta-carboline | CH...)
Show SMILES [O-][N+](=O)c1ccc(Cl)c(c1)-c1nccc2c1[nH]c1ccccc21
Show InChI InChI=1S/C17H10ClN3O2/c18-14-6-5-10(21(22)23)9-13(14)16-17-12(7-8-19-16)11-3-1-2-4-15(11)20-17/h1-9,20H
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n/an/a 2.20E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 2-cyclin A


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (Human))
BDBM50111435
PNG
(7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445)
Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12
Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3
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n/an/a 2.40E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 5-p35nck5a


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3


(Homo sapiens (Human))
BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a 2.50E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 5-p35nck5a


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (Human))
BDBM50111435
PNG
(7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445)
Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12
Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3
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n/an/a 3.00E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 2-cyclin A


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (Human))
BDBM100152
PNG
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
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n/an/a 3.50E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 2-cyclin A


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3


(Homo sapiens (Human))
BDBM50111435
PNG
(7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445)
Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12
Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3
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n/an/a 4.20E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cell division cycle 2 (CDK1)-cyclin B


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3


(Homo sapiens (Human))
BDBM50111433
PNG
(1-(2-Chloro-5-nitro-phenyl)-9H-beta-carboline | CH...)
Show SMILES [O-][N+](=O)c1ccc(Cl)c(c1)-c1nccc2c1[nH]c1ccccc21
Show InChI InChI=1S/C17H10ClN3O2/c18-14-6-5-10(21(22)23)9-13(14)16-17-12(7-8-19-16)11-3-1-2-4-15(11)20-17/h1-9,20H
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n/an/a 4.50E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cell division cycle 2 (CDK1)-cyclin B


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50111435
PNG
(7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445)
Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12
Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (Human))
BDBM50111433
PNG
(1-(2-Chloro-5-nitro-phenyl)-9H-beta-carboline | CH...)
Show SMILES [O-][N+](=O)c1ccc(Cl)c(c1)-c1nccc2c1[nH]c1ccccc21
Show InChI InChI=1S/C17H10ClN3O2/c18-14-6-5-10(21(22)23)9-13(14)16-17-12(7-8-19-16)11-3-1-2-4-15(11)20-17/h1-9,20H
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Fyn kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (Human))
BDBM100152
PNG
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Fyn kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM50111433
PNG
(1-(2-Chloro-5-nitro-phenyl)-9H-beta-carboline | CH...)
Show SMILES [O-][N+](=O)c1ccc(Cl)c(c1)-c1nccc2c1[nH]c1ccccc21
Show InChI InChI=1S/C17H10ClN3O2/c18-14-6-5-10(21(22)23)9-13(14)16-17-12(7-8-19-16)11-3-1-2-4-15(11)20-17/h1-9,20H
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Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Lyn tyrosine kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM50111435
PNG
(7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445)
Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12
Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Lyn tyrosine kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM100152
PNG
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Protein kinase C (PKC)


(Homo sapiens (Human))
BDBM100152
PNG
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of protein kinase C


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (Human))
BDBM50111435
PNG
(7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445)
Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12
Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Fyn kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50111433
PNG
(1-(2-Chloro-5-nitro-phenyl)-9H-beta-carboline | CH...)
Show SMILES [O-][N+](=O)c1ccc(Cl)c(c1)-c1nccc2c1[nH]c1ccccc21
Show InChI InChI=1S/C17H10ClN3O2/c18-14-6-5-10(21(22)23)9-13(14)16-17-12(7-8-19-16)11-3-1-2-4-15(11)20-17/h1-9,20H
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM100152
PNG
(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Lyn tyrosine kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Protein kinase C (PKC)


(Homo sapiens (Human))
BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of protein kinase C


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Lyn tyrosine kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (Human))
BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Fyn kinase


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Protein kinase C (PKC)


(Homo sapiens (Human))
BDBM50111435
PNG
(7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445)
Show SMILES Cc1nccc2c3ccc(F)cc3[nH]c12
Show InChI InChI=1S/C12H9FN2/c1-7-12-10(4-5-14-7)9-3-2-8(13)6-11(9)15-12/h2-6,15H,1H3
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of protein kinase C


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Protein kinase C (PKC)


(Homo sapiens (Human))
BDBM50111433
PNG
(1-(2-Chloro-5-nitro-phenyl)-9H-beta-carboline | CH...)
Show SMILES [O-][N+](=O)c1ccc(Cl)c(c1)-c1nccc2c1[nH]c1ccccc21
Show InChI InChI=1S/C17H10ClN3O2/c18-14-6-5-10(21(22)23)9-13(14)16-17-12(7-8-19-16)11-3-1-2-4-15(11)20-17/h1-9,20H
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of protein kinase C


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (Human))
BDBM50111433
PNG
(1-(2-Chloro-5-nitro-phenyl)-9H-beta-carboline | CH...)
Show SMILES [O-][N+](=O)c1ccc(Cl)c(c1)-c1nccc2c1[nH]c1ccccc21
Show InChI InChI=1S/C17H10ClN3O2/c18-14-6-5-10(21(22)23)9-13(14)16-17-12(7-8-19-16)11-3-1-2-4-15(11)20-17/h1-9,20H
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n/an/a>1.20E+6n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 5-p35nck5a


Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%