Affinity Data by PubMed id=11916147

PubMed code 11916147

Found 11 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM85568 (7-Hydroxy-flavone, 5c) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(Br)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM85567 (7-Hydroxy-flavone, 5b) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(F)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM26664 (7-Hydroxy-flavone, 5a \| 7-Hydroxyflavone, 11 \| 7-h...) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM85570 (7-Hydroxy-flavone, 5e) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(cc1)N(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50011438 (2-(4-Amino-phenyl)-7-hydroxy-chromen-4-one \| 2-(4-...) Show SMILES Nc1ccc(cc1)-c1cc(=O)c2ccc(O)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM85569 (7-Hydroxy-flavone, 5d) Show SMILES Oc1ccc2c(c1)oc(cc2=O)-c1ccc(I)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM85573 (7-Hydroxy-flavone, 5h) Show SMILES COc1ccc(cc1)-c1cc(=O)c2ccc(O)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM85574 (7-Hydroxy-flavone, 7) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM85571 (7-Hydroxy-flavone, 5f) Show SMILES Cc1ccc(cc1)-c1cc(=O)c2ccc(O)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM85575 (7-Hydroxy-flavone, 8) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM85572 (7-Hydroxy-flavone, 5g) Show SMILES CCCCc1ccc(cc1)-c1cc(=O)c2ccc(O)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.				J Enzym Inhib 16: 417-24 (2001) Article DOI: 10.1080/14756360109162390 BindingDB Entry DOI: 10.7270/Q2FJ2FBS
Cardiff University					More data for this Ligand-Target Pair

* indicates data uncertainty>20%