Affinity Data by PubMed id=11992771

PubMed code 11992771

Found 19 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112833 (CHEMBL280587 \| N-(1-Benzyl-2-carbamoyl-2-oxo-ethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50073850 ((S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-butyr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112845 (CHEMBL280654 \| N-(1-Benzyl-2-oxo-ethyl)-2-(2-napht...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112835 (CHEMBL282979 \| N-(1-Benzyl-2-oxo-ethyl)-2-[2-(3,4-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112843 (Biphenyl-2-carboxylic acid (1-benzyl-2-carbamoyl-2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112844 (CHEMBL27036 \| N-(1-Benzyl-2-oxo-ethyl)-2-(naphthal...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112846 (CHEMBL28203 \| N-(1-Benzyl-2-oxo-ethyl)-2-phenoxy-b...) Show SMILES O=CC(Cc1ccccc1)NC(=O)c1ccccc1Oc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112832 (CHEMBL441599 \| N-(1-Benzyl-2-carbamoyl-2-oxo-ethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112842 (Biphenyl-2-carboxylic acid (1-benzyl-2-oxo-ethyl)-...) Show SMILES O=CC(Cc1ccccc1)NC(=O)c1ccccc1-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50112833 (CHEMBL280587 \| N-(1-Benzyl-2-carbamoyl-2-oxo-ethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of cathepsin B				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112839 (CHEMBL26631 \| N-(1-Benzyl-2-oxo-ethyl)-2-styryl-be...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112837 (CHEMBL281731 \| N-(1-Benzyl-2-oxo-ethyl)-2-naphthal...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112836 (2-Benzoyl-N-(1-benzyl-2-oxo-ethyl)-benzamide \| CHE...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112840 (CHEMBL26870 \| N-(1-Benzyl-2-oxo-ethyl)-2-phenethyl...) Show SMILES O=CC(Cc1ccccc1)NC(=O)c1ccccc1CCc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112847 (2-Benzyl-N-(1-benzyl-2-oxo-ethyl)-benzamide \| CHEM...) Show SMILES O=CC(Cc1ccccc1)NC(=O)c1ccccc1Cc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112841 (CHEMBL280652 \| N-(1-Benzyl-2-oxo-ethyl)-2-phenoxym...) Show SMILES O=CC(Cc1ccccc1)NC(=O)c1ccccc1COc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112834 (CHEMBL27250 \| N-(1-Benzyl-2-oxo-ethyl)-2-phenyleth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50112838 (CHEMBL281874 \| N-(1-Benzyl-2-oxo-ethyl)-benzamide) Show SMILES O=CC(Cc1ccccc1)NC(=O)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description Inhibition of calpain, using human mu-calpain isolated from erythrocytes and Suc-Leu-Tyr-AMC as the fluorogenic substrate				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50112833 (CHEMBL280587 \| N-(1-Benzyl-2-carbamoyl-2-oxo-ethyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott GmbH&Co. KG Curated by ChEMBL					Assay Description The compound was evaluated for inhibition of cathepsin L				Bioorg Med Chem Lett 12: 1335-8 (2002) BindingDB Entry DOI: 10.7270/Q2W0958R
Abbott GmbH&Co. KG Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%