Affinity Data by PubMed id=12036350

PubMed code 12036350

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113768 ((S)-methyl 2-(4-hydroxybenzylideneamino)-3-(1H-ind...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113775 (2-[(4-Hydroxy-benzylidene)-amino]-3-(4-hydroxy-phe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113773 (2-[(4-Hydroxy-benzylidene)-amino]-3-(1H-indol-3-yl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113772 (2-[(4-Hydroxy-benzylidene)-amino]-3-phenyl-propion...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113774 (2-[(4-Hydroxy-benzylidene)-amino]-butyric acid met...) Show SMILES CC[C@H](\N=C\c1ccc(O)cc1)C(=O)OC \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113767 (2-[(4-Hydroxy-benzylidene)-amino]-5-methylsulfanyl...) Show SMILES COC(=O)[C@H](CCCSC)\N=C\c1ccc(O)cc1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113771 (2-[(4-Hydroxy-benzylidene)-amino]-4-methyl-pentano...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113769 (2-[(4-Hydroxy-benzylidene)-amino]-propionic acid m...) Show SMILES COC(=O)[C@H](C)\N=C\c1ccc(O)cc1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113770 (4-Hydroxy-2-[(4-hydroxy-benzylidene)-amino]-butyri...) Show SMILES COC(=O)[C@H](CCO)\N=C\c1ccc(O)cc1 \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
Institute for Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%