Affinity Data by PubMed id=12113827

PubMed code 12113827

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50115831 (1-Methyl-2-(4-methyl-benzo[1,2-b;5,4-b']difuran-8-...) Show SMILES CC(N)Cc1c2occc2c(C)c2ccoc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2C receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50115831 (1-Methyl-2-(4-methyl-benzo[1,2-b;5,4-b']difuran-8-...) Show SMILES CC(N)Cc1c2occc2c(C)c2ccoc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2A receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50115830 (1-Methyl-2-(4-methyl-2,3,5,6-tetrahydro-benzo[1,2-...) Show SMILES CC(N)Cc1c2OCCc2c(C)c2CCOc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2A receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50115830 (1-Methyl-2-(4-methyl-2,3,5,6-tetrahydro-benzo[1,2-...) Show SMILES CC(N)Cc1c2OCCc2c(C)c2CCOc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2C receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005265 ((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...) Show SMILES COc1cc(CC(C)N)c(OC)cc1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [125I]-(R)-DOI from 5-hydroxytryptamine 2A receptor in cloned rat prefrontal cortex homogenate				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50115832 (1-(2,6-dimethoxy-4-methylphenyl)propan-2-amine \| 2...) Show SMILES COc1cc(C)cc(OC)c1CC(C)N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2A receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50115832 (1-(2,6-dimethoxy-4-methylphenyl)propan-2-amine \| 2...) Show SMILES COc1cc(C)cc(OC)c1CC(C)N Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2C receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%