Affinity Data by PubMed id=12161113

PubMed code 12161113

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50111940 ((R)-4-[(R)-2-Cyclohexylmethylsulfanyl-1-(4-phenoxy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells				Bioorg Med Chem Lett 12: 2267-9 (2002) BindingDB Entry DOI: 10.7270/Q2VH5N60
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50116658 ((R)-4-[(R)-2-Cyclohexylmethylsulfanyl-1-(1-phenyl-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells				Bioorg Med Chem Lett 12: 2267-9 (2002) BindingDB Entry DOI: 10.7270/Q2VH5N60
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50116653 ((R)-4-[(R)-1-(1-Benzyl-piperidin-4-ylcarbamoyl)-2-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells				Bioorg Med Chem Lett 12: 2267-9 (2002) BindingDB Entry DOI: 10.7270/Q2VH5N60
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50116657 ((R)-4-[(R)-2-(4-Benzyl-piperazin-1-yl)-1-cyclohexy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells				Bioorg Med Chem Lett 12: 2267-9 (2002) BindingDB Entry DOI: 10.7270/Q2VH5N60
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50116652 ((R)-4-[(R)-1-(2-Benzylamino-ethylcarbamoyl)-2-cycl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells				Bioorg Med Chem Lett 12: 2267-9 (2002) BindingDB Entry DOI: 10.7270/Q2VH5N60
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50116655 ((R)-4-[(R)-1-Cyclohexylmethylsulfanylmethyl-2-oxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells				Bioorg Med Chem Lett 12: 2267-9 (2002) BindingDB Entry DOI: 10.7270/Q2VH5N60
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50116654 ((R)-4-[(R)-2-(4-Benzylamino-piperidin-1-yl)-1-cycl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells				Bioorg Med Chem Lett 12: 2267-9 (2002) BindingDB Entry DOI: 10.7270/Q2VH5N60
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Homo sapiens (Human))	BDBM50116656 ((R)-4-[(R)-1-Cyclohexylmethylsulfanylmethyl-2-oxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channel influx in IMR-32 human neuroblastoma cells				Bioorg Med Chem Lett 12: 2267-9 (2002) BindingDB Entry DOI: 10.7270/Q2VH5N60
Minase Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%