Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM14459 ((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM14457 ((+)-4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117937 ((+)4-(2-{4-[9-bromo-4-chloro-1-methyl-(12R)-3,6,7,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117932 ((+/-)4-{2-[4-(9-bromo-4-chloro-1-methyl-3,6,7,12-t...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117931 ((-)4-(2-{4-[4-chloro-1-methyl-(12R)-3,6,7,12-tetra...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117931 ((-)4-(2-{4-[4-chloro-1-methyl-(12R)-3,6,7,12-tetra...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117933 ((+)1-[4-(10-Bromo-8-chloro-6,11-dihydro-5H-benzo[5...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117939 ((+)1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117935 ((+)4-{2-[4-(4-chloro-3,6,7,12-tetrahydropyrido[2',...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117936 ((+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetra...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117938 ((+)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrah...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117938 ((+)4-(2-{4-[1-butyl-4-chloro-(12R)-3,6,7,12-tetrah...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >180 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117934 ((+ )1-[4-(4-chloro-1,3-dimethyl-3,6,7,12-tetrahydr...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >190 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50117936 ((+)4-(2-{4-[4-chloro-1-propyl-(12R)-3,6,7,12-tetra...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >190 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Protein farnesyltransferase in Cos-1 monkey kidney cells expressing H-Ras-val | J Med Chem 45: 3854-64 (2002) BindingDB Entry DOI: 10.7270/Q2TD9WPB | |||||||||||
More data for this Ligand-Target Pair |