Found 96 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanocortin receptor 3
(Mus musculus) | BDBM50122058
(Ac-His-D-Phe-Arg-D-Dip-NH2 | CHEMBL358833)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122063
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 51.9 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50034910
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122062
(Ac-His-D-Phe-Arg-Atc-NH2 | CHEMBL153420)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCc2ccccc2C1)C(N)=O Show InChI InChI=1S/C34H44N10O5/c1-21(45)41-28(17-25-19-38-20-40-25)30(47)43-27(16-22-8-3-2-4-9-22)29(46)42-26(12-7-15-39-33(36)37)31(48)44-34(32(35)49)14-13-23-10-5-6-11-24(23)18-34/h2-6,8-11,19-20,26-28H,7,12-18H2,1H3,(H2,35,49)(H,38,40)(H,41,45)(H,42,46)(H,43,47)(H,44,48)(H4,36,37,39)/t26-,27-,28-,34?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 960 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122058
(Ac-His-D-Phe-Arg-D-Dip-NH2 | CHEMBL358833)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 680 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122062
(Ac-His-D-Phe-Arg-Atc-NH2 | CHEMBL153420)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCc2ccccc2C1)C(N)=O Show InChI InChI=1S/C34H44N10O5/c1-21(45)41-28(17-25-19-38-20-40-25)30(47)43-27(16-22-8-3-2-4-9-22)29(46)42-26(12-7-15-39-33(36)37)31(48)44-34(32(35)49)14-13-23-10-5-6-11-24(23)18-34/h2-6,8-11,19-20,26-28H,7,12-18H2,1H3,(H2,35,49)(H,38,40)(H,41,45)(H,42,46)(H,43,47)(H,44,48)(H4,36,37,39)/t26-,27-,28-,34?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122075
(Ac-His-D-Phe-Arg-4Pal-NH2 | CHEMBL433522)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccncc1)C(N)=O Show InChI InChI=1S/C31H41N11O5/c1-19(43)39-26(16-22-17-36-18-38-22)30(47)42-25(15-20-6-3-2-4-7-20)29(46)40-23(8-5-11-37-31(33)34)28(45)41-24(27(32)44)14-21-9-12-35-13-10-21/h2-4,6-7,9-10,12-13,17-18,23-26H,5,8,11,14-16H2,1H3,(H2,32,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,33,34,37)/t23-,24+,25-,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122072
(Ac-His-D-Phe-Arg-Dip-NH2 | CHEMBL152555)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 5.33E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122071
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122075
(Ac-His-D-Phe-Arg-4Pal-NH2 | CHEMBL433522)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccncc1)C(N)=O Show InChI InChI=1S/C31H41N11O5/c1-19(43)39-26(16-22-17-36-18-38-22)30(47)42-25(15-20-6-3-2-4-7-20)29(46)40-23(8-5-11-37-31(33)34)28(45)41-24(27(32)44)14-21-9-12-35-13-10-21/h2-4,6-7,9-10,12-13,17-18,23-26H,5,8,11,14-16H2,1H3,(H2,32,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,33,34,37)/t23-,24+,25-,26-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122076
(Ac-His-D-Phe-Arg-D-Nal(2')-NH2 | CHEMBL347216)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 5.37 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50409674
(CHEMBL2096693)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O Show InChI InChI=1S/C33H42N10O5/c1-20(44)40-27(16-24-17-37-19-39-24)31(47)42-26(14-21-8-3-2-4-9-21)30(46)41-25(12-7-13-38-33(35)36)32(48)43-18-23-11-6-5-10-22(23)15-28(43)29(34)45/h2-6,8-11,17,19,25-28H,7,12-16,18H2,1H3,(H2,34,45)(H,37,39)(H,40,44)(H,41,46)(H,42,47)(H4,35,36,38)/t25-,26+,27-,28-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122059
(Ac-His-D-Phe-Arg-Trp-NH2 | CHEMBL152612)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27?,28-,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 156 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122065
(Ac-His-D-Phe-Arg-2Thi-NH2 | CHEMBL349795)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccs1)C(N)=O Show InChI InChI=1S/C30H40N10O5S/c1-18(41)37-25(14-20-16-34-17-36-20)29(45)40-24(13-19-7-3-2-4-8-19)28(44)38-22(10-5-11-35-30(32)33)27(43)39-23(26(31)42)15-21-9-6-12-46-21/h2-4,6-9,12,16-17,22-25H,5,10-11,13-15H2,1H3,(H2,31,42)(H,34,36)(H,37,41)(H,38,44)(H,39,43)(H,40,45)(H4,32,33,35)/t22-,23+,24-,25-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.78E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122066
(Ac-His-D-Phe-Arg-Nal(2')-NH2 | CHEMBL357558)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 17.9 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122070
(Ac-His-D-Phe-Arg-D-Bip-NH2 | CHEMBL348901)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122070
(Ac-His-D-Phe-Arg-D-Bip-NH2 | CHEMBL348901)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.62E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122074
(Ac-His-D-Phe-Arg-3Bal-NH2 | CHEMBL151906)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1csc2ccccc12)C(N)=O Show InChI InChI=1S/C34H42N10O5S/c1-20(45)41-28(16-23-17-38-19-40-23)33(49)44-27(14-21-8-3-2-4-9-21)32(48)42-25(11-7-13-39-34(36)37)31(47)43-26(30(35)46)15-22-18-50-29-12-6-5-10-24(22)29/h2-6,8-10,12,17-19,25-28H,7,11,13-16H2,1H3,(H2,35,46)(H,38,40)(H,41,45)(H,42,48)(H,43,47)(H,44,49)(H4,36,37,39)/t25-,26+,27-,28-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 143 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122069
(Ac-His-D-Phe-Arg-D-Phe-NH2 | CHEMBL154251)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25-,26-,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122063
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122059
(Ac-His-D-Phe-Arg-Trp-NH2 | CHEMBL152612)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27?,28-,29-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 17.2 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122062
(Ac-His-D-Phe-Arg-Atc-NH2 | CHEMBL153420)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCc2ccccc2C1)C(N)=O Show InChI InChI=1S/C34H44N10O5/c1-21(45)41-28(17-25-19-38-20-40-25)30(47)43-27(16-22-8-3-2-4-9-22)29(46)42-26(12-7-15-39-33(36)37)31(48)44-34(32(35)49)14-13-23-10-5-6-11-24(23)18-34/h2-6,8-11,19-20,26-28H,7,12-18H2,1H3,(H2,35,49)(H,38,40)(H,41,45)(H,42,46)(H,43,47)(H,44,48)(H4,36,37,39)/t26-,27-,28-,34?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122059
(Ac-His-D-Phe-Arg-Trp-NH2 | CHEMBL152612)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27?,28-,29-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.96 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122074
(Ac-His-D-Phe-Arg-3Bal-NH2 | CHEMBL151906)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1csc2ccccc12)C(N)=O Show InChI InChI=1S/C34H42N10O5S/c1-20(45)41-28(16-23-17-38-19-40-23)33(49)44-27(14-21-8-3-2-4-9-21)32(48)42-25(11-7-13-39-34(36)37)31(47)43-26(30(35)46)15-22-18-50-29-12-6-5-10-24(22)29/h2-6,8-10,12,17-19,25-28H,7,11,13-16H2,1H3,(H2,35,46)(H,38,40)(H,41,45)(H,42,48)(H,43,47)(H,44,49)(H4,36,37,39)/t25-,26+,27-,28-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 79.9 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122066
(Ac-His-D-Phe-Arg-Nal(2')-NH2 | CHEMBL357558)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.86 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122065
(Ac-His-D-Phe-Arg-2Thi-NH2 | CHEMBL349795)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccs1)C(N)=O Show InChI InChI=1S/C30H40N10O5S/c1-18(41)37-25(14-20-16-34-17-36-20)29(45)40-24(13-19-7-3-2-4-8-19)28(44)38-22(10-5-11-35-30(32)33)27(43)39-23(26(31)42)15-21-9-6-12-46-21/h2-4,6-9,12,16-17,22-25H,5,10-11,13-15H2,1H3,(H2,31,42)(H,34,36)(H,37,41)(H,38,44)(H,39,43)(H,40,45)(H4,32,33,35)/t22-,23+,24-,25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 8.12E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122071
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122076
(Ac-His-D-Phe-Arg-D-Nal(2')-NH2 | CHEMBL347216)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 46.2 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50034910
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0380 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50034910
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 35.3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122068
(Ac-His-D-Phe-Arg-Ala-NH2 | CHEMBL359318)Show SMILES CC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(N)=O Show InChI InChI=1S/C26H38N10O5/c1-15(22(27)38)33-23(39)19(9-6-10-31-26(28)29)35-24(40)20(11-17-7-4-3-5-8-17)36-25(41)21(34-16(2)37)12-18-13-30-14-32-18/h3-5,7-8,13-15,19-21H,6,9-12H2,1-2H3,(H2,27,38)(H,30,32)(H,33,39)(H,34,37)(H,35,40)(H,36,41)(H4,28,29,31)/t15?,19-,20-,21-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122070
(Ac-His-D-Phe-Arg-D-Bip-NH2 | CHEMBL348901)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122072
(Ac-His-D-Phe-Arg-Dip-NH2 | CHEMBL152555)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50034910
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122068
(Ac-His-D-Phe-Arg-Ala-NH2 | CHEMBL359318)Show SMILES CC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(N)=O Show InChI InChI=1S/C26H38N10O5/c1-15(22(27)38)33-23(39)19(9-6-10-31-26(28)29)35-24(40)20(11-17-7-4-3-5-8-17)36-25(41)21(34-16(2)37)12-18-13-30-14-32-18/h3-5,7-8,13-15,19-21H,6,9-12H2,1-2H3,(H2,27,38)(H,30,32)(H,33,39)(H,34,37)(H,35,40)(H,36,41)(H4,28,29,31)/t15?,19-,20-,21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.37E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122069
(Ac-His-D-Phe-Arg-D-Phe-NH2 | CHEMBL154251)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25-,26-,27-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 470 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50184359
((3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexan...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r,wU:21.75,50.52,12.11,4.4,39.41,wD:25.25,61.64,(19.68,-11.7,;18.32,-10.97,;18.27,-9.43,;16.91,-8.71,;16.86,-7.17,;18.17,-6.36,;18.11,-4.82,;19.42,-4,;16.76,-4.09,;15.5,-6.44,;15.45,-4.9,;14.19,-7.26,;12.83,-6.53,;11.53,-7.35,;11.58,-8.88,;12.94,-9.61,;10.27,-9.7,;8.91,-8.97,;7.6,-9.79,;6.25,-9.06,;4.94,-9.87,;3.58,-9.15,;3.53,-7.61,;2.17,-6.88,;.86,-7.7,;2.12,-5.35,;.76,-4.62,;.71,-3.08,;1.93,-2.14,;1.41,-.69,;-.14,-.74,;-1.21,.35,;-2.69,-.02,;-3.1,-1.51,;-2.03,-2.6,;-.56,-2.22,;3.43,-4.53,;4.79,-5.26,;4.84,-6.8,;6.98,-5.22,;8.76,-4.36,;10.12,-5.08,;10.17,-6.62,;8.86,-7.43,;7.5,-6.71,;6.19,-7.52,;8.83,-5.93,;6.09,-4.44,;6.04,-2.9,;4.68,-2.18,;7.35,-2.09,;7.3,-.55,;5.94,.17,;5.89,1.71,;4.53,2.44,;3.23,1.62,;3.28,.07,;4.64,-.64,;8.71,-2.82,;10.02,-2,;9.96,-.46,;11.37,-2.73,;12.68,-1.91,;12.64,-.37,;13.86,.56,;13.35,2.01,;11.81,1.97,;11.37,.5,;11.42,-4.27,;12.78,-4.99,;14.09,-4.18,;2.27,-9.96,;.91,-9.24,;2.32,-11.5,)| Show InChI InChI=1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122062
(Ac-His-D-Phe-Arg-Atc-NH2 | CHEMBL153420)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCc2ccccc2C1)C(N)=O Show InChI InChI=1S/C34H44N10O5/c1-21(45)41-28(17-25-19-38-20-40-25)30(47)43-27(16-22-8-3-2-4-9-22)29(46)42-26(12-7-15-39-33(36)37)31(48)44-34(32(35)49)14-13-23-10-5-6-11-24(23)18-34/h2-6,8-11,19-20,26-28H,7,12-18H2,1H3,(H2,35,49)(H,38,40)(H,41,45)(H,42,46)(H,43,47)(H,44,48)(H4,36,37,39)/t26-,27-,28-,34?/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122067
(Ac-His-D-Phe-Arg-D-Nal(1')-NH2 | CHEMBL346925)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122068
(Ac-His-D-Phe-Arg-Ala-NH2 | CHEMBL359318)Show SMILES CC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(N)=O Show InChI InChI=1S/C26H38N10O5/c1-15(22(27)38)33-23(39)19(9-6-10-31-26(28)29)35-24(40)20(11-17-7-4-3-5-8-17)36-25(41)21(34-16(2)37)12-18-13-30-14-32-18/h3-5,7-8,13-15,19-21H,6,9-12H2,1-2H3,(H2,27,38)(H,30,32)(H,33,39)(H,34,37)(H,35,40)(H,36,41)(H4,28,29,31)/t15?,19-,20-,21-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.84E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122069
(Ac-His-D-Phe-Arg-D-Phe-NH2 | CHEMBL154251)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25-,26-,27-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122072
(Ac-His-D-Phe-Arg-Dip-NH2 | CHEMBL152555)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122061
(Ac-His-D-Phe-Arg-Phe-NH2 | CHEMBL152986)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25+,26-,27-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122073
(Ac-His-D-Phe-Arg-Nal(1')-NH2 | CHEMBL154153)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 730 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122067
(Ac-His-D-Phe-Arg-D-Nal(1')-NH2 | CHEMBL346925)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.19E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122063
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122075
(Ac-His-D-Phe-Arg-4Pal-NH2 | CHEMBL433522)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccncc1)C(N)=O Show InChI InChI=1S/C31H41N11O5/c1-19(43)39-26(16-22-17-36-18-38-22)30(47)42-25(15-20-6-3-2-4-7-20)29(46)40-23(8-5-11-37-31(33)34)28(45)41-24(27(32)44)14-21-9-12-35-13-10-21/h2-4,6-7,9-10,12-13,17-18,23-26H,5,8,11,14-16H2,1H3,(H2,32,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,33,34,37)/t23-,24+,25-,26-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122076
(Ac-His-D-Phe-Arg-D-Nal(2')-NH2 | CHEMBL347216)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 12.1 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50409673
(CHEMBL2096745)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O Show InChI InChI=1S/C33H42N10O5/c1-20(44)40-27(16-24-17-37-19-39-24)31(47)42-26(14-21-8-3-2-4-9-21)30(46)41-25(12-7-13-38-33(35)36)32(48)43-18-23-11-6-5-10-22(23)15-28(43)29(34)45/h2-6,8-11,17,19,25-28H,7,12-16,18H2,1H3,(H2,34,45)(H,37,39)(H,40,44)(H,41,46)(H,42,47)(H4,35,36,38)/t25-,26+,27-,28+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50409673
(CHEMBL2096745)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O Show InChI InChI=1S/C33H42N10O5/c1-20(44)40-27(16-24-17-37-19-39-24)31(47)42-26(14-21-8-3-2-4-9-21)30(46)41-25(12-7-13-38-33(35)36)32(48)43-18-23-11-6-5-10-22(23)15-28(43)29(34)45/h2-6,8-11,17,19,25-28H,7,12-16,18H2,1H3,(H2,34,45)(H,37,39)(H,40,44)(H,41,46)(H,42,47)(H4,35,36,38)/t25-,26+,27-,28+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.48E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50409674
(CHEMBL2096693)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O Show InChI InChI=1S/C33H42N10O5/c1-20(44)40-27(16-24-17-37-19-39-24)31(47)42-26(14-21-8-3-2-4-9-21)30(46)41-25(12-7-13-38-33(35)36)32(48)43-18-23-11-6-5-10-22(23)15-28(43)29(34)45/h2-6,8-11,17,19,25-28H,7,12-16,18H2,1H3,(H2,34,45)(H,37,39)(H,40,44)(H,41,46)(H,42,47)(H4,35,36,38)/t25-,26+,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.32E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50409674
(CHEMBL2096693)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O Show InChI InChI=1S/C33H42N10O5/c1-20(44)40-27(16-24-17-37-19-39-24)31(47)42-26(14-21-8-3-2-4-9-21)30(46)41-25(12-7-13-38-33(35)36)32(48)43-18-23-11-6-5-10-22(23)15-28(43)29(34)45/h2-6,8-11,17,19,25-28H,7,12-16,18H2,1H3,(H2,34,45)(H,37,39)(H,40,44)(H,41,46)(H,42,47)(H4,35,36,38)/t25-,26+,27-,28-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0980 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122061
(Ac-His-D-Phe-Arg-Phe-NH2 | CHEMBL152986)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25+,26-,27-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 890 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122063
(Ac-His-D-Phe-Arg-Bip-NH2 | CHEMBL347364)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31+,32-,33-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122068
(Ac-His-D-Phe-Arg-Ala-NH2 | CHEMBL359318)Show SMILES CC(NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(N)=O Show InChI InChI=1S/C26H38N10O5/c1-15(22(27)38)33-23(39)19(9-6-10-31-26(28)29)35-24(40)20(11-17-7-4-3-5-8-17)36-25(41)21(34-16(2)37)12-18-13-30-14-32-18/h3-5,7-8,13-15,19-21H,6,9-12H2,1-2H3,(H2,27,38)(H,30,32)(H,33,39)(H,34,37)(H,35,40)(H,36,41)(H4,28,29,31)/t15?,19-,20-,21-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122065
(Ac-His-D-Phe-Arg-2Thi-NH2 | CHEMBL349795)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccs1)C(N)=O Show InChI InChI=1S/C30H40N10O5S/c1-18(41)37-25(14-20-16-34-17-36-20)29(45)40-24(13-19-7-3-2-4-8-19)28(44)38-22(10-5-11-35-30(32)33)27(43)39-23(26(31)42)15-21-9-6-12-46-21/h2-4,6-9,12,16-17,22-25H,5,10-11,13-15H2,1H3,(H2,31,42)(H,34,36)(H,37,41)(H,38,44)(H,39,43)(H,40,45)(H4,32,33,35)/t22-,23+,24-,25-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 850 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122061
(Ac-His-D-Phe-Arg-Phe-NH2 | CHEMBL152986)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25+,26-,27-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 530 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122075
(Ac-His-D-Phe-Arg-4Pal-NH2 | CHEMBL433522)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccncc1)C(N)=O Show InChI InChI=1S/C31H41N11O5/c1-19(43)39-26(16-22-17-36-18-38-22)30(47)42-25(15-20-6-3-2-4-7-20)29(46)40-23(8-5-11-37-31(33)34)28(45)41-24(27(32)44)14-21-9-12-35-13-10-21/h2-4,6-7,9-10,12-13,17-18,23-26H,5,8,11,14-16H2,1H3,(H2,32,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,33,34,37)/t23-,24+,25-,26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122062
(Ac-His-D-Phe-Arg-Atc-NH2 | CHEMBL153420)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCc2ccccc2C1)C(N)=O Show InChI InChI=1S/C34H44N10O5/c1-21(45)41-28(17-25-19-38-20-40-25)30(47)43-27(16-22-8-3-2-4-9-22)29(46)42-26(12-7-15-39-33(36)37)31(48)44-34(32(35)49)14-13-23-10-5-6-11-24(23)18-34/h2-6,8-11,19-20,26-28H,7,12-18H2,1H3,(H2,35,49)(H,38,40)(H,41,45)(H,42,46)(H,43,47)(H,44,48)(H4,36,37,39)/t26-,27-,28-,34?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122066
(Ac-His-D-Phe-Arg-Nal(2')-NH2 | CHEMBL357558)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 740 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50409674
(CHEMBL2096693)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O Show InChI InChI=1S/C33H42N10O5/c1-20(44)40-27(16-24-17-37-19-39-24)31(47)42-26(14-21-8-3-2-4-9-21)30(46)41-25(12-7-13-38-33(35)36)32(48)43-18-23-11-6-5-10-22(23)15-28(43)29(34)45/h2-6,8-11,17,19,25-28H,7,12-16,18H2,1H3,(H2,34,45)(H,37,39)(H,40,44)(H,41,46)(H,42,47)(H4,35,36,38)/t25-,26+,27-,28-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50409673
(CHEMBL2096745)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O Show InChI InChI=1S/C33H42N10O5/c1-20(44)40-27(16-24-17-37-19-39-24)31(47)42-26(14-21-8-3-2-4-9-21)30(46)41-25(12-7-13-38-33(35)36)32(48)43-18-23-11-6-5-10-22(23)15-28(43)29(34)45/h2-6,8-11,17,19,25-28H,7,12-16,18H2,1H3,(H2,34,45)(H,37,39)(H,40,44)(H,41,46)(H,42,47)(H4,35,36,38)/t25-,26+,27-,28+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.94E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122058
(Ac-His-D-Phe-Arg-D-Dip-NH2 | CHEMBL358833)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.44E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122067
(Ac-His-D-Phe-Arg-D-Nal(1')-NH2 | CHEMBL346925)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122067
(Ac-His-D-Phe-Arg-D-Nal(1')-NH2 | CHEMBL346925)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50029747
((4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(2S...)Show SMILES CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O Show InChI InChI=1S/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.440 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122058
(Ac-His-D-Phe-Arg-D-Dip-NH2 | CHEMBL358833)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(c1ccccc1)c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50409673
(CHEMBL2096745)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O Show InChI InChI=1S/C33H42N10O5/c1-20(44)40-27(16-24-17-37-19-39-24)31(47)42-26(14-21-8-3-2-4-9-21)30(46)41-25(12-7-13-38-33(35)36)32(48)43-18-23-11-6-5-10-22(23)15-28(43)29(34)45/h2-6,8-11,17,19,25-28H,7,12-16,18H2,1H3,(H2,34,45)(H,37,39)(H,40,44)(H,41,46)(H,42,47)(H4,35,36,38)/t25-,26+,27-,28+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50184359
((3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexan...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r,wU:21.75,50.52,12.11,4.4,39.41,wD:25.25,61.64,(19.68,-11.7,;18.32,-10.97,;18.27,-9.43,;16.91,-8.71,;16.86,-7.17,;18.17,-6.36,;18.11,-4.82,;19.42,-4,;16.76,-4.09,;15.5,-6.44,;15.45,-4.9,;14.19,-7.26,;12.83,-6.53,;11.53,-7.35,;11.58,-8.88,;12.94,-9.61,;10.27,-9.7,;8.91,-8.97,;7.6,-9.79,;6.25,-9.06,;4.94,-9.87,;3.58,-9.15,;3.53,-7.61,;2.17,-6.88,;.86,-7.7,;2.12,-5.35,;.76,-4.62,;.71,-3.08,;1.93,-2.14,;1.41,-.69,;-.14,-.74,;-1.21,.35,;-2.69,-.02,;-3.1,-1.51,;-2.03,-2.6,;-.56,-2.22,;3.43,-4.53,;4.79,-5.26,;4.84,-6.8,;6.98,-5.22,;8.76,-4.36,;10.12,-5.08,;10.17,-6.62,;8.86,-7.43,;7.5,-6.71,;6.19,-7.52,;8.83,-5.93,;6.09,-4.44,;6.04,-2.9,;4.68,-2.18,;7.35,-2.09,;7.3,-.55,;5.94,.17,;5.89,1.71,;4.53,2.44,;3.23,1.62,;3.28,.07,;4.64,-.64,;8.71,-2.82,;10.02,-2,;9.96,-.46,;11.37,-2.73,;12.68,-1.91,;12.64,-.37,;13.86,.56,;13.35,2.01,;11.81,1.97,;11.37,.5,;11.42,-4.27,;12.78,-4.99,;14.09,-4.18,;2.27,-9.96,;.91,-9.24,;2.32,-11.5,)| Show InChI InChI=1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50184359
((3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexan...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r,wU:21.75,50.52,12.11,4.4,39.41,wD:25.25,61.64,(19.68,-11.7,;18.32,-10.97,;18.27,-9.43,;16.91,-8.71,;16.86,-7.17,;18.17,-6.36,;18.11,-4.82,;19.42,-4,;16.76,-4.09,;15.5,-6.44,;15.45,-4.9,;14.19,-7.26,;12.83,-6.53,;11.53,-7.35,;11.58,-8.88,;12.94,-9.61,;10.27,-9.7,;8.91,-8.97,;7.6,-9.79,;6.25,-9.06,;4.94,-9.87,;3.58,-9.15,;3.53,-7.61,;2.17,-6.88,;.86,-7.7,;2.12,-5.35,;.76,-4.62,;.71,-3.08,;1.93,-2.14,;1.41,-.69,;-.14,-.74,;-1.21,.35,;-2.69,-.02,;-3.1,-1.51,;-2.03,-2.6,;-.56,-2.22,;3.43,-4.53,;4.79,-5.26,;4.84,-6.8,;6.98,-5.22,;8.76,-4.36,;10.12,-5.08,;10.17,-6.62,;8.86,-7.43,;7.5,-6.71,;6.19,-7.52,;8.83,-5.93,;6.09,-4.44,;6.04,-2.9,;4.68,-2.18,;7.35,-2.09,;7.3,-.55,;5.94,.17,;5.89,1.71,;4.53,2.44,;3.23,1.62,;3.28,.07,;4.64,-.64,;8.71,-2.82,;10.02,-2,;9.96,-.46,;11.37,-2.73,;12.68,-1.91,;12.64,-.37,;13.86,.56,;13.35,2.01,;11.81,1.97,;11.37,.5,;11.42,-4.27,;12.78,-4.99,;14.09,-4.18,;2.27,-9.96,;.91,-9.24,;2.32,-11.5,)| Show InChI InChI=1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0870 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122071
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.76E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122059
(Ac-His-D-Phe-Arg-Trp-NH2 | CHEMBL152612)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27?,28-,29-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 20.1 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122066
(Ac-His-D-Phe-Arg-Nal(2')-NH2 | CHEMBL357558)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 15.8 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122072
(Ac-His-D-Phe-Arg-Dip-NH2 | CHEMBL152555)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(c1ccccc1)c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-31(21-28-22-42-23-44-28)37(53)47-30(20-25-12-5-2-6-13-25)36(52)46-29(18-11-19-43-38(40)41)35(51)48-33(34(39)50)32(26-14-7-3-8-15-26)27-16-9-4-10-17-27/h2-10,12-17,22-23,29-33H,11,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,53)(H,48,51)(H4,40,41,43)/t29-,30-,31-,33+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122076
(Ac-His-D-Phe-Arg-D-Nal(2')-NH2 | CHEMBL347216)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-27-20-40-21-42-27)35(51)46-30(17-23-8-3-2-4-9-23)34(50)44-28(12-7-15-41-36(38)39)33(49)45-29(32(37)48)18-24-13-14-25-10-5-6-11-26(25)16-24/h2-6,8-11,13-14,16,20-21,28-31H,7,12,15,17-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29-,30-,31-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 127 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50122062
(Ac-His-D-Phe-Arg-Atc-NH2 | CHEMBL153420)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCc2ccccc2C1)C(N)=O Show InChI InChI=1S/C34H44N10O5/c1-21(45)41-28(17-25-19-38-20-40-25)30(47)43-27(16-22-8-3-2-4-9-22)29(46)42-26(12-7-15-39-33(36)37)31(48)44-34(32(35)49)14-13-23-10-5-6-11-24(23)18-34/h2-6,8-11,19-20,26-28H,7,12-18H2,1H3,(H2,35,49)(H,38,40)(H,41,45)(H,42,46)(H,43,47)(H,44,48)(H4,36,37,39)/t26-,27-,28-,34?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 680 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122061
(Ac-His-D-Phe-Arg-Phe-NH2 | CHEMBL152986)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25+,26-,27-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122062
(Ac-His-D-Phe-Arg-Atc-NH2 | CHEMBL153420)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCc2ccccc2C1)C(N)=O Show InChI InChI=1S/C34H44N10O5/c1-21(45)41-28(17-25-19-38-20-40-25)30(47)43-27(16-22-8-3-2-4-9-22)29(46)42-26(12-7-15-39-33(36)37)31(48)44-34(32(35)49)14-13-23-10-5-6-11-24(23)18-34/h2-6,8-11,19-20,26-28H,7,12-18H2,1H3,(H2,35,49)(H,38,40)(H,41,45)(H,42,46)(H,43,47)(H,44,48)(H4,36,37,39)/t26-,27-,28-,34?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.46E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122069
(Ac-His-D-Phe-Arg-D-Phe-NH2 | CHEMBL154251)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C32H42N10O5/c1-20(43)39-27(17-23-18-36-19-38-23)31(47)42-26(16-22-11-6-3-7-12-22)30(46)40-24(13-8-14-37-32(34)35)29(45)41-25(28(33)44)15-21-9-4-2-5-10-21/h2-7,9-12,18-19,24-27H,8,13-17H2,1H3,(H2,33,44)(H,36,38)(H,39,43)(H,40,46)(H,41,45)(H,42,47)(H4,34,35,37)/t24-,25-,26-,27-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122070
(Ac-His-D-Phe-Arg-D-Bip-NH2 | CHEMBL348901)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O Show InChI InChI=1S/C38H46N10O5/c1-24(49)45-33(21-29-22-42-23-44-29)37(53)48-32(20-25-9-4-2-5-10-25)36(52)46-30(13-8-18-43-38(40)41)35(51)47-31(34(39)50)19-26-14-16-28(17-15-26)27-11-6-3-7-12-27/h2-7,9-12,14-17,22-23,30-33H,8,13,18-21H2,1H3,(H2,39,50)(H,42,44)(H,45,49)(H,46,52)(H,47,51)(H,48,53)(H4,40,41,43)/t30-,31-,32-,33-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122062
(Ac-His-D-Phe-Arg-Atc-NH2 | CHEMBL153420)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCc2ccccc2C1)C(N)=O Show InChI InChI=1S/C34H44N10O5/c1-21(45)41-28(17-25-19-38-20-40-25)30(47)43-27(16-22-8-3-2-4-9-22)29(46)42-26(12-7-15-39-33(36)37)31(48)44-34(32(35)49)14-13-23-10-5-6-11-24(23)18-34/h2-6,8-11,19-20,26-28H,7,12-18H2,1H3,(H2,35,49)(H,38,40)(H,41,45)(H,42,46)(H,43,47)(H,44,48)(H4,36,37,39)/t26-,27-,28-,34?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.35E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122071
(Ac-His-D-Phe-Arg-His-NH2 | CHEMBL350012)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cnc[nH]1)C(N)=O Show InChI InChI=1S/C29H40N12O5/c1-17(42)38-24(12-20-14-34-16-37-20)28(46)41-23(10-18-6-3-2-4-7-18)27(45)39-21(8-5-9-35-29(31)32)26(44)40-22(25(30)43)11-19-13-33-15-36-19/h2-4,6-7,13-16,21-24H,5,8-12H2,1H3,(H2,30,43)(H,33,36)(H,34,37)(H,38,42)(H,39,45)(H,40,44)(H,41,46)(H4,31,32,35)/t21-,22+,23-,24-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122073
(Ac-His-D-Phe-Arg-Nal(1')-NH2 | CHEMBL154153)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122065
(Ac-His-D-Phe-Arg-2Thi-NH2 | CHEMBL349795)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccs1)C(N)=O Show InChI InChI=1S/C30H40N10O5S/c1-18(41)37-25(14-20-16-34-17-36-20)29(45)40-24(13-19-7-3-2-4-8-19)28(44)38-22(10-5-11-35-30(32)33)27(43)39-23(26(31)42)15-21-9-6-12-46-21/h2-4,6-9,12,16-17,22-25H,5,10-11,13-15H2,1H3,(H2,31,42)(H,34,36)(H,37,41)(H,38,44)(H,39,43)(H,40,45)(H4,32,33,35)/t22-,23+,24-,25-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.03E+4 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50121900
(Ac-Ser-Try-Ser-Nle-Glu-His-DPhe-Arg-Trp-Gly-Lys-Pr...)Show SMILES CCCC[C@H](NC(=O)C(CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C(C)C)C(N)=O Show InChI InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61?,62+,65+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0710 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50122073
(Ac-His-D-Phe-Arg-Nal(1')-NH2 | CHEMBL154153)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50122074
(Ac-His-D-Phe-Arg-3Bal-NH2 | CHEMBL151906)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1csc2ccccc12)C(N)=O Show InChI InChI=1S/C34H42N10O5S/c1-20(45)41-28(16-23-17-38-19-40-23)33(49)44-27(14-21-8-3-2-4-9-21)32(48)42-25(11-7-13-39-34(36)37)31(47)43-26(30(35)46)15-22-18-50-29-12-6-5-10-24(22)29/h2-6,8-10,12,17-19,25-28H,7,11,13-16H2,1H3,(H2,35,46)(H,38,40)(H,41,45)(H,42,48)(H,43,47)(H,44,49)(H4,36,37,39)/t25-,26+,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-3 receptor (mMC3R) stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122074
(Ac-His-D-Phe-Arg-3Bal-NH2 | CHEMBL151906)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1csc2ccccc12)C(N)=O Show InChI InChI=1S/C34H42N10O5S/c1-20(45)41-28(16-23-17-38-19-40-23)33(49)44-27(14-21-8-3-2-4-9-21)32(48)42-25(11-7-13-39-34(36)37)31(47)43-26(30(35)46)15-22-18-50-29-12-6-5-10-24(22)29/h2-6,8-10,12,17-19,25-28H,7,11,13-16H2,1H3,(H2,35,46)(H,38,40)(H,41,45)(H,42,48)(H,43,47)(H,44,49)(H4,36,37,39)/t25-,26+,27-,28-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 47.7 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50122073
(Ac-His-D-Phe-Arg-Nal(1')-NH2 | CHEMBL154153)Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O Show InChI InChI=1S/C36H44N10O5/c1-22(47)43-31(19-26-20-40-21-42-26)35(51)46-30(17-23-9-3-2-4-10-23)34(50)44-28(15-8-16-41-36(38)39)33(49)45-29(32(37)48)18-25-13-7-12-24-11-5-6-14-27(24)25/h2-7,9-14,20-21,28-31H,8,15-19H2,1H3,(H2,37,48)(H,40,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,38,39,41)/t28-,29+,30-,31-/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 33.1 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-5 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50184359
((3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexan...)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r,wU:21.75,50.52,12.11,4.4,39.41,wD:25.25,61.64,(19.68,-11.7,;18.32,-10.97,;18.27,-9.43,;16.91,-8.71,;16.86,-7.17,;18.17,-6.36,;18.11,-4.82,;19.42,-4,;16.76,-4.09,;15.5,-6.44,;15.45,-4.9,;14.19,-7.26,;12.83,-6.53,;11.53,-7.35,;11.58,-8.88,;12.94,-9.61,;10.27,-9.7,;8.91,-8.97,;7.6,-9.79,;6.25,-9.06,;4.94,-9.87,;3.58,-9.15,;3.53,-7.61,;2.17,-6.88,;.86,-7.7,;2.12,-5.35,;.76,-4.62,;.71,-3.08,;1.93,-2.14,;1.41,-.69,;-.14,-.74,;-1.21,.35,;-2.69,-.02,;-3.1,-1.51,;-2.03,-2.6,;-.56,-2.22,;3.43,-4.53,;4.79,-5.26,;4.84,-6.8,;6.98,-5.22,;8.76,-4.36,;10.12,-5.08,;10.17,-6.62,;8.86,-7.43,;7.5,-6.71,;6.19,-7.52,;8.83,-5.93,;6.09,-4.44,;6.04,-2.9,;4.68,-2.18,;7.35,-2.09,;7.3,-.55,;5.94,.17,;5.89,1.71,;4.53,2.44,;3.23,1.62,;3.28,.07,;4.64,-.64,;8.71,-2.82,;10.02,-2,;9.96,-.46,;11.37,-2.73,;12.68,-1.91,;12.64,-.37,;13.86,.56,;13.35,2.01,;11.81,1.97,;11.37,.5,;11.42,-4.27,;12.78,-4.99,;14.09,-4.18,;2.27,-9.96,;.91,-9.24,;2.32,-11.5,)| Show InChI InChI=1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a |
University of Florida
Curated by ChEMBL
| Assay Description
Activity in mouse melanocortin-1 receptor stably expressed in HEK293 cells |
J Med Chem 45: 5736-44 (2002)
BindingDB Entry DOI: 10.7270/Q2Q2410R |
More data for this
Ligand-Target Pair | |
Search and Browse
