Affinity Data by PubMed id=12538898

PubMed code 12538898

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peptide deformylase (Haemophilus influenzae)	BDBM21683 (N-hydroxy-N-(3-phenylpropyl)formamide \| SB-485345) Show SMILES ON(CCCc1ccccc1)C=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli (strain K12))	BDBM21683 (N-hydroxy-N-(3-phenylpropyl)formamide \| SB-485345) Show SMILES ON(CCCc1ccccc1)C=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair				3D Structure (crystal)
Peptide deformylase (Staphylococcus aureus)	BDBM21683 (N-hydroxy-N-(3-phenylpropyl)formamide \| SB-485345) Show SMILES ON(CCCc1ccccc1)C=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair
Peptide deformylase (Haemophilus influenzae)	BDBM21684 (N-[2-(3-benzoylphenoxy)ethyl]-N-hydroxyformamide \|...) Show SMILES ON(CCOc1cccc(c1)C(=O)c1ccccc1)C=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair
Peptide deformylase (Streptococcus pneumoniae (strain ATCC BAA-255 / R6...)	BDBM21683 (N-hydroxy-N-(3-phenylpropyl)formamide \| SB-485345) Show SMILES ON(CCCc1ccccc1)C=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair				3D Structure (crystal)
Peptide deformylase (Haemophilus influenzae)	BDBM21685 (N-hydroxy-N-[3-(6-methylpyridin-2-yl)propyl]formam...) Show SMILES Cc1cccc(CCCN(O)C=O)n1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair
Peptide deformylase (Staphylococcus aureus)	BDBM21685 (N-hydroxy-N-[3-(6-methylpyridin-2-yl)propyl]formam...) Show SMILES Cc1cccc(CCCN(O)C=O)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli (strain K12))	BDBM21684 (N-[2-(3-benzoylphenoxy)ethyl]-N-hydroxyformamide \|...) Show SMILES ON(CCOc1cccc(c1)C(=O)c1ccccc1)C=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair
Peptide deformylase (Streptococcus pneumoniae (strain ATCC BAA-255 / R6...)	BDBM21685 (N-hydroxy-N-[3-(6-methylpyridin-2-yl)propyl]formam...) Show SMILES Cc1cccc(CCCN(O)C=O)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	DrugBank MMDB PDB Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair				3D Structure (crystal)
Peptide deformylase (Staphylococcus aureus)	BDBM21684 (N-[2-(3-benzoylphenoxy)ethyl]-N-hydroxyformamide \|...) Show SMILES ON(CCOc1cccc(c1)C(=O)c1ccccc1)C=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair
Peptide deformylase (Escherichia coli (strain K12))	BDBM21685 (N-hydroxy-N-[3-(6-methylpyridin-2-yl)propyl]formam...) Show SMILES Cc1cccc(CCCN(O)C=O)n1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair
Peptide deformylase (Streptococcus pneumoniae (strain ATCC BAA-255 / R6...)	BDBM21684 (N-[2-(3-benzoylphenoxy)ethyl]-N-hydroxyformamide \|...) Show SMILES ON(CCOc1cccc(c1)C(=O)c1ccccc1)C=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem	DrugBank MMDB PDB Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	7.6	25
GSK					Assay Description Enzyme assay was carried out in 96-well microtiter plates with a SpectraMax plate reader (Molecular Devices Corp.). PDF activity was measured using a...				Protein Sci 12: 349-60 (2003) Article DOI: 10.1110/ps.0229303 BindingDB Entry DOI: 10.7270/Q2F18X1N
GSK					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%