Affinity Data by PubMed id=12565935

PubMed code 12565935

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50123067 ((S)-1-Benzyl-3-isobutyl-4-(toluene-4-sulfonyl)-pip...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Oxford Centre for Molecular Sciences and The Dyson Perrins Laboratory Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against human neutrophil elastase (HNE)				Bioorg Med Chem Lett 13: 387-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V7S
					More data for this Ligand-Target Pair
Chymotrypsin-like elastase family member 2A (Sus scrofa)	BDBM50123067 ((S)-1-Benzyl-3-isobutyl-4-(toluene-4-sulfonyl)-pip...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Oxford Centre for Molecular Sciences and The Dyson Perrins Laboratory Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against porcine pancreatic elastase (PPE)				Bioorg Med Chem Lett 13: 387-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V7S
					More data for this Ligand-Target Pair
Chymotrypsin-like elastase family member 2A (Sus scrofa)	BDBM50123068 ((S)-2-sec-Butyl-3-oxo-4-(toluene-4-sulfonyl)-piper...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.93E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Oxford Centre for Molecular Sciences and The Dyson Perrins Laboratory Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against porcine pancreatic elastase (PPE)				Bioorg Med Chem Lett 13: 387-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V7S
					More data for this Ligand-Target Pair
Chymotrypsin-like elastase family member 2A (Sus scrofa)	BDBM50123066 ((S)-2-Isobutyl-4-methanesulfonyl-3-oxo-piperazine-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9.23E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Oxford Centre for Molecular Sciences and The Dyson Perrins Laboratory Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against porcine pancreatic elastase (PPE)				Bioorg Med Chem Lett 13: 387-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V7S
					More data for this Ligand-Target Pair
Chymotrypsin-like elastase family member 2A (Sus scrofa)	BDBM50123065 ((S)-1-Benzyl-3-isobutyl-4-methanesulfonyl-piperazi...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
The Oxford Centre for Molecular Sciences and The Dyson Perrins Laboratory Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against porcine pancreatic elastase (PPE)				Bioorg Med Chem Lett 13: 387-9 (2003) BindingDB Entry DOI: 10.7270/Q2319V7S
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%