Affinity Data by PubMed id=12643898

PubMed code 12643898

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur Strasbourg BP 24 Curated by ChEMBL					Assay Description In vitro inhibitory potency for preventing ET-1 induced constriction of rat aortic rings (ETA receptor)				Bioorg Med Chem Lett 13: 1001-4 (2003) BindingDB Entry DOI: 10.7270/Q2WW7JV4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50125187 (2-(2-Chloro-pyrimidin-5-yl)-7-aza-bicyclo[2.2.1]he...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur Strasbourg BP 24 Curated by ChEMBL					Assay Description In vitro inhibitory potency for preventing sarafotoxin S6c induced constriction of rat tracheal rings (ETB receptor)				Bioorg Med Chem Lett 13: 1001-4 (2003) BindingDB Entry DOI: 10.7270/Q2WW7JV4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50125188 (CHEMBL268176 \| N-[5-(7-Aza-bicyclo[2.2.1]hept-2-yl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur Strasbourg BP 24 Curated by ChEMBL					Assay Description In vitro inhibitory potency for preventing ET-1 induced constriction of rat aortic rings (ETA receptor)				Bioorg Med Chem Lett 13: 1001-4 (2003) BindingDB Entry DOI: 10.7270/Q2WW7JV4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50125189 (CHEMBL267191 \| [5-(7-Aza-bicyclo[2.2.1]hept-2-yl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Louis Pasteur Strasbourg BP 24 Curated by ChEMBL					Assay Description In vitro inhibitory potency for preventing ET-1 induced constriction of rat aortic rings (ETA receptor)				Bioorg Med Chem Lett 13: 1001-4 (2003) BindingDB Entry DOI: 10.7270/Q2WW7JV4
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%