Found 109 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222968
(Cipralisant | GT-2331)Show InChI InChI=1S/C14H20N2/c1-14(2,3)7-5-4-6-11-8-12(11)13-9-15-10-16-13/h9-12H,5,7-8H2,1-3H3,(H,15,16)/t11-,12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.195 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 0.490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222963
(CHEMBL24863)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCC(C)CC1 Show InChI InChI=1S/C28H38N2O2/c1-21-15-18-29(19-16-21)28(31)26-9-7-24(8-10-26)25-11-13-27(14-12-25)32-20-4-17-30-22(2)5-6-23(30)3/h7-14,21-23H,4-6,15-20H2,1-3H3/t22-,23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.603 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222941
(CHEMBL27501)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C26H34N2O2/c1-20-6-7-21(2)28(20)18-5-19-30-25-14-12-23(13-15-25)22-8-10-24(11-9-22)26(29)27-16-3-4-17-27/h8-15,20-21H,3-7,16-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.692 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223042
(CHEMBL283313)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2[C@@H](C)CC[C@@H]2C)cc1 Show InChI InChI=1S/C26H36N2O2/c1-5-27(6-2)26(29)24-12-10-22(11-13-24)23-14-16-25(17-15-23)30-19-7-18-28-20(3)8-9-21(28)4/h10-17,20-21H,5-9,18-19H2,1-4H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.776 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223041
(CHEMBL280590)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1C Show InChI InChI=1S/C27H36N2O2/c1-20-6-4-17-29(20)27(30)25-11-9-23(10-12-25)24-13-15-26(16-14-24)31-19-5-18-28-21(2)7-8-22(28)3/h9-16,20-22H,4-8,17-19H2,1-3H3/t20?,21-,22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| PubMed
| 0.776 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223048
(CHEMBL25519)Show SMILES CC(C)NC(=O)c1ccc(cc1)-c1ccc(OCCCN2[C@@H](C)CC[C@@H]2C)cc1 Show InChI InChI=1S/C25H34N2O2/c1-18(2)26-25(28)23-10-8-21(9-11-23)22-12-14-24(15-13-22)29-17-5-16-27-19(3)6-7-20(27)4/h8-15,18-20H,5-7,16-17H2,1-4H3,(H,26,28)/t19-,20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.851 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222951
(CHEMBL27933)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1[C@@H](C)CC[C@@H]1C Show InChI InChI=1S/C28H38N2O2/c1-20-6-7-21(2)29(20)18-5-19-32-27-16-14-25(15-17-27)24-10-12-26(13-11-24)28(31)30-22(3)8-9-23(30)4/h10-17,20-23H,5-9,18-19H2,1-4H3/t20-,21-,22-,23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.977 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223041
(CHEMBL280590)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1C Show InChI InChI=1S/C27H36N2O2/c1-20-6-4-17-29(20)27(30)25-11-9-23(10-12-25)24-13-15-26(16-14-24)31-19-5-18-28-21(2)7-8-22(28)3/h9-16,20-22H,4-8,17-19H2,1-3H3/t20?,21-,22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222973
(CHEMBL26880)Show SMILES O=C(N1CCCC1)c1ccc(cc1)-c1ccc(OCCCN2CCCC2)cc1 Show InChI InChI=1S/C24H30N2O2/c27-24(26-17-3-4-18-26)22-8-6-20(7-9-22)21-10-12-23(13-11-21)28-19-5-16-25-14-1-2-15-25/h6-13H,1-5,14-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223042
(CHEMBL283313)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2[C@@H](C)CC[C@@H]2C)cc1 Show InChI InChI=1S/C26H36N2O2/c1-5-27(6-2)26(29)24-12-10-22(11-13-24)23-14-16-25(17-15-23)30-19-7-18-28-20(3)8-9-21(28)4/h10-17,20-21H,5-9,18-19H2,1-4H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222968
(Cipralisant | GT-2331)Show InChI InChI=1S/C14H20N2/c1-14(2,3)7-5-4-6-11-8-12(11)13-9-15-10-16-13/h9-12H,5,7-8H2,1-3H3,(H,15,16)/t11-,12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222948
(CHEMBL25342)Show SMILES CC(C)NC(=O)c1ccc(cc1)-c1ccc(OCCCN2CCC(C)CC2)cc1 Show InChI InChI=1S/C25H34N2O2/c1-19(2)26-25(28)23-7-5-21(6-8-23)22-9-11-24(12-10-22)29-18-4-15-27-16-13-20(3)14-17-27/h5-12,19-20H,4,13-18H2,1-3H3,(H,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222950
(CHEMBL279463)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1C Show InChI InChI=1S/C25H34N2O2/c1-4-26(5-2)17-7-19-29-24-15-13-22(14-16-24)21-9-11-23(12-10-21)25(28)27-18-6-8-20(27)3/h9-16,20H,4-8,17-19H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222964
(CHEMBL27697)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H32N2O3/c1-3-25(4-2)14-5-17-29-23-12-10-21(11-13-23)20-6-8-22(9-7-20)24(27)26-15-18-28-19-16-26/h6-13H,3-5,14-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223038
(CHEMBL433031)Show SMILES CC1CCCN1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCC(C)CC2)cc1 Show InChI InChI=1S/C27H36N2O2/c1-21-14-18-28(19-15-21)16-4-20-31-26-12-10-24(11-13-26)23-6-8-25(9-7-23)27(30)29-17-3-5-22(29)2/h6-13,21-22H,3-5,14-20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223048
(CHEMBL25519)Show SMILES CC(C)NC(=O)c1ccc(cc1)-c1ccc(OCCCN2[C@@H](C)CC[C@@H]2C)cc1 Show InChI InChI=1S/C25H34N2O2/c1-18(2)26-25(28)23-10-8-21(9-11-23)22-12-14-24(15-13-22)29-17-5-16-27-19(3)6-7-20(27)4/h8-15,18-20H,5-7,16-17H2,1-4H3,(H,26,28)/t19-,20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222957
(CHEMBL2113223)Show SMILES CN(C)[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCCC2)C1 Show InChI InChI=1S/C26H35N3O2/c1-27(2)24-14-18-28(20-24)15-5-19-31-25-12-10-22(11-13-25)21-6-8-23(9-7-21)26(30)29-16-3-4-17-29/h6-13,24H,3-5,14-20H2,1-2H3/t24-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222952
(CHEMBL27665)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C24H32N2O2/c1-3-25(4-2)16-7-19-28-23-14-12-21(13-15-23)20-8-10-22(11-9-20)24(27)26-17-5-6-18-26/h8-15H,3-7,16-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222963
(CHEMBL24863)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCC(C)CC1 Show InChI InChI=1S/C28H38N2O2/c1-21-15-18-29(19-16-21)28(31)26-9-7-24(8-10-26)25-11-13-27(14-12-25)32-20-4-17-30-22(2)5-6-23(30)3/h7-14,21-23H,4-6,15-20H2,1-3H3/t22-,23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222938
(CHEMBL25685)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCC(C)CC1 Show InChI InChI=1S/C26H36N2O2/c1-4-27(5-2)17-6-20-30-25-13-11-23(12-14-25)22-7-9-24(10-8-22)26(29)28-18-15-21(3)16-19-28/h7-14,21H,4-6,15-20H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222960
(CHEMBL27444)Show SMILES CC1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCCC2)CC1 Show InChI InChI=1S/C26H34N2O2/c1-21-13-18-27(19-14-21)15-4-20-30-25-11-9-23(10-12-25)22-5-7-24(8-6-22)26(29)28-16-2-3-17-28/h5-12,21H,2-4,13-20H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223043
(CHEMBL25205)Show SMILES C[C@H]1CC[C@H](C)N1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCC(C)CC2)cc1 Show InChI InChI=1S/C28H38N2O2/c1-21-15-18-29(19-16-21)17-4-20-32-27-13-11-25(12-14-27)24-7-9-26(10-8-24)28(31)30-22(2)5-6-23(30)3/h7-14,21-23H,4-6,15-20H2,1-3H3/t22-,23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223038
(CHEMBL433031)Show SMILES CC1CCCN1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCC(C)CC2)cc1 Show InChI InChI=1S/C27H36N2O2/c1-21-14-18-28(19-15-21)16-4-20-31-26-12-10-24(11-13-26)23-6-8-25(9-7-23)27(30)29-17-3-5-22(29)2/h6-13,21-22H,3-5,14-20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222948
(CHEMBL25342)Show SMILES CC(C)NC(=O)c1ccc(cc1)-c1ccc(OCCCN2CCC(C)CC2)cc1 Show InChI InChI=1S/C25H34N2O2/c1-19(2)26-25(28)23-7-5-21(6-8-23)22-9-11-24(12-10-22)29-18-4-15-27-16-13-20(3)14-17-27/h5-12,19-20H,4,13-18H2,1-3H3,(H,26,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222959
(CHEMBL2113224)Show SMILES CC1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](C2)N(C)C)cc1 Show InChI InChI=1S/C28H39N3O2/c1-22-13-18-31(19-14-22)28(32)25-7-5-23(6-8-25)24-9-11-27(12-10-24)33-20-4-16-30-17-15-26(21-30)29(2)3/h5-12,22,26H,4,13-21H2,1-3H3/t26-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222951
(CHEMBL27933)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1[C@@H](C)CC[C@@H]1C Show InChI InChI=1S/C28H38N2O2/c1-20-6-7-21(2)29(20)18-5-19-32-27-16-14-25(15-17-27)24-10-12-26(13-11-24)28(31)30-22(3)8-9-23(30)4/h10-17,20-23H,5-9,18-19H2,1-4H3/t20-,21-,22-,23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223044
(CHEMBL436340)Show SMILES C[C@H]1CC[C@H](C)N1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@@H](C2)N(C)C)cc1 Show InChI InChI=1S/C28H39N3O2/c1-21-6-7-22(2)31(21)28(32)25-10-8-23(9-11-25)24-12-14-27(15-13-24)33-19-5-17-30-18-16-26(20-30)29(3)4/h8-15,21-22,26H,5-7,16-20H2,1-4H3/t21-,22-,26-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223043
(CHEMBL25205)Show SMILES C[C@H]1CC[C@H](C)N1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCC(C)CC2)cc1 Show InChI InChI=1S/C28H38N2O2/c1-21-15-18-29(19-16-21)17-4-20-32-27-13-11-25(12-14-27)24-7-9-26(10-8-24)28(31)30-22(2)5-6-23(30)3/h7-14,21-23H,4-6,15-20H2,1-3H3/t22-,23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223040
(CHEMBL281640)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCC(C)CC2)cc1 Show InChI InChI=1S/C26H36N2O2/c1-4-28(5-2)26(29)24-9-7-22(8-10-24)23-11-13-25(14-12-23)30-20-6-17-27-18-15-21(3)16-19-27/h7-14,21H,4-6,15-20H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 4.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222969
(CHEMBL282903)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1[C@@H](C)CC[C@@H]1C Show InChI InChI=1S/C26H36N2O2/c1-5-27(6-2)18-7-19-30-25-16-14-23(15-17-25)22-10-12-24(13-11-22)26(29)28-20(3)8-9-21(28)4/h10-17,20-21H,5-9,18-19H2,1-4H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222941
(CHEMBL27501)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C26H34N2O2/c1-20-6-7-21(2)28(20)18-5-19-30-25-14-12-23(13-15-25)22-8-10-24(11-9-22)26(29)27-16-3-4-17-27/h8-15,20-21H,3-7,16-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222965
(CHEMBL2113222)Show SMILES CN(C)[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 Show InChI InChI=1S/C26H35N3O3/c1-27(2)24-12-14-28(20-24)13-3-17-32-25-10-8-22(9-11-25)21-4-6-23(7-5-21)26(30)29-15-18-31-19-16-29/h4-11,24H,3,12-20H2,1-2H3/t24-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222939
(CHEMBL24468)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)NC(C)C Show InChI InChI=1S/C23H32N2O2/c1-5-25(6-2)16-7-17-27-22-14-12-20(13-15-22)19-8-10-21(11-9-19)23(26)24-18(3)4/h8-15,18H,5-7,16-17H2,1-4H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222967
(CHEMBL24198)Show SMILES O[C@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 Show InChI InChI=1S/C24H30N2O4/c27-22-10-12-25(18-22)11-1-15-30-23-8-6-20(7-9-23)19-2-4-21(5-3-19)24(28)26-13-16-29-17-14-26/h2-9,22,27H,1,10-18H2/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222958
(CHEMBL27339)Show SMILES O[C@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCCC2)C1 Show InChI InChI=1S/C24H30N2O3/c27-22-12-16-25(18-22)13-3-17-29-23-10-8-20(9-11-23)19-4-6-21(7-5-19)24(28)26-14-1-2-15-26/h4-11,22,27H,1-3,12-18H2/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222961
(CHEMBL27835)Show SMILES CC1CCCN1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@@H](C2)N(C)C)cc1 Show InChI InChI=1S/C27H37N3O2/c1-21-6-4-17-30(21)27(31)24-9-7-22(8-10-24)23-11-13-26(14-12-23)32-19-5-16-29-18-15-25(20-29)28(2)3/h7-14,21,25H,4-6,15-20H2,1-3H3/t21?,25-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222973
(CHEMBL26880)Show SMILES O=C(N1CCCC1)c1ccc(cc1)-c1ccc(OCCCN2CCCC2)cc1 Show InChI InChI=1S/C24H30N2O2/c27-24(26-17-3-4-18-26)22-8-6-20(7-9-22)21-10-12-23(13-11-21)28-19-5-16-25-14-1-2-15-25/h6-13H,1-5,14-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222946
(CHEMBL280895)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@@H](C2)N(C)C)cc1 Show InChI InChI=1S/C26H37N3O2/c1-5-29(6-2)26(30)23-10-8-21(9-11-23)22-12-14-25(15-13-22)31-19-7-17-28-18-16-24(20-28)27(3)4/h8-15,24H,5-7,16-20H2,1-4H3/t24-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222954
(CHEMBL24865)Show SMILES CC1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-20-11-16-28(17-12-20)26(30)23-5-3-21(4-6-23)22-7-9-25(10-8-22)31-18-2-14-27-15-13-24(29)19-27/h3-10,20,24,29H,2,11-19H2,1H3/t24-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50217101
(CHEMBL25688)Show InChI InChI=1S/C20H22N2O/c21-16-17-4-6-18(7-5-17)19-8-10-20(11-9-19)23-15-3-14-22-12-1-2-13-22/h4-11H,1-3,12-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222950
(CHEMBL279463)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1C Show InChI InChI=1S/C25H34N2O2/c1-4-26(5-2)17-7-19-29-24-15-13-22(14-16-24)21-9-11-23(12-10-21)25(28)27-18-6-8-20(27)3/h9-16,20H,4-8,17-19H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223039
(CHEMBL27209)Show SMILES CC1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCOCC2)CC1 Show InChI InChI=1S/C26H34N2O3/c1-21-11-14-27(15-12-21)13-2-18-31-25-9-7-23(8-10-25)22-3-5-24(6-4-22)26(29)28-16-19-30-20-17-28/h3-10,21H,2,11-20H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222949
(CHEMBL282062)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C24H32N2O3/c1-3-26(4-2)24(28)21-8-6-19(7-9-21)20-10-12-23(13-11-20)29-17-5-15-25-16-14-22(27)18-25/h6-13,22,27H,3-5,14-18H2,1-2H3/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222940
(CHEMBL282685)Show SMILES CC(C)N(C)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C24H32N2O3/c1-18(2)25(3)24(28)21-7-5-19(6-8-21)20-9-11-23(12-10-20)29-16-4-14-26-15-13-22(27)17-26/h5-12,18,22,27H,4,13-17H2,1-3H3/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222938
(CHEMBL25685)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCC(C)CC1 Show InChI InChI=1S/C26H36N2O2/c1-4-27(5-2)17-6-20-30-25-13-11-23(12-14-25)22-7-9-24(10-8-22)26(29)28-18-15-21(3)16-19-28/h7-14,21H,4-6,15-20H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223037
(CHEMBL25501)Show SMILES CC1CCCN1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C25H32N2O3/c1-19-4-2-15-27(19)25(29)22-7-5-20(6-8-22)21-9-11-24(12-10-21)30-17-3-14-26-16-13-23(28)18-26/h5-12,19,23,28H,2-4,13-18H2,1H3/t19?,23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223039
(CHEMBL27209)Show SMILES CC1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCOCC2)CC1 Show InChI InChI=1S/C26H34N2O3/c1-21-11-14-27(15-12-21)13-2-18-31-25-9-7-23(8-10-25)22-3-5-24(6-4-22)26(29)28-16-19-30-20-17-28/h3-10,21H,2,11-20H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222964
(CHEMBL27697)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C24H32N2O3/c1-3-25(4-2)14-5-17-29-23-12-10-21(11-13-23)20-6-8-22(9-7-20)24(27)26-15-18-28-19-16-26/h6-13H,3-5,14-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223040
(CHEMBL281640)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCC(C)CC2)cc1 Show InChI InChI=1S/C26H36N2O2/c1-4-28(5-2)26(29)24-9-7-22(8-10-24)23-11-13-25(14-12-23)30-20-6-17-27-18-15-21(3)16-19-27/h7-14,21H,4-6,15-20H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 9.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222947
(CHEMBL24921)Show SMILES CC(C)NCCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1C Show InChI InChI=1S/C24H32N2O2/c1-18(2)25-15-5-17-28-23-13-11-21(12-14-23)20-7-9-22(10-8-20)24(27)26-16-4-6-19(26)3/h7-14,18-19,25H,4-6,15-17H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222960
(CHEMBL27444)Show SMILES CC1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCCC2)CC1 Show InChI InChI=1S/C26H34N2O2/c1-21-13-18-27(19-14-21)15-4-20-30-25-11-9-23(10-12-25)22-5-7-24(8-6-22)26(29)28-16-2-3-17-28/h5-12,21H,2-4,13-20H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222970
(CHEMBL27115)Show SMILES CC1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCC(C)CC2)CC1 Show InChI InChI=1S/C28H38N2O2/c1-22-12-17-29(18-13-22)16-3-21-32-27-10-8-25(9-11-27)24-4-6-26(7-5-24)28(31)30-19-14-23(2)15-20-30/h4-11,22-23H,3,12-21H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222971
(CHEMBL282016)Show SMILES C[C@H]1CC[C@H](C)N1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-19-4-5-20(2)28(19)26(30)23-8-6-21(7-9-23)22-10-12-25(13-11-22)31-17-3-15-27-16-14-24(29)18-27/h6-13,19-20,24,29H,3-5,14-18H2,1-2H3/t19-,20-,24-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222952
(CHEMBL27665)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1 Show InChI InChI=1S/C24H32N2O2/c1-3-25(4-2)16-7-19-28-23-14-12-21(13-15-23)20-8-10-22(11-9-20)24(27)26-17-5-6-18-26/h8-15H,3-7,16-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222969
(CHEMBL282903)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1[C@@H](C)CC[C@@H]1C Show InChI InChI=1S/C26H36N2O2/c1-5-27(6-2)18-7-19-30-25-16-14-23(15-17-25)22-10-12-24(13-11-22)26(29)28-20(3)8-9-21(28)4/h10-17,20-21H,5-9,18-19H2,1-4H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222939
(CHEMBL24468)Show SMILES CCN(CC)CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)NC(C)C Show InChI InChI=1S/C23H32N2O2/c1-5-25(6-2)16-7-17-27-22-14-12-20(13-15-22)19-8-10-21(11-9-19)23(26)24-18(3)4/h8-15,18H,5-7,16-17H2,1-4H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222956
(CHEMBL24352)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C24H32N2O3/c1-3-26(4-2)24(27)22-8-6-20(7-9-22)21-10-12-23(13-11-21)29-17-5-14-25-15-18-28-19-16-25/h6-13H,3-5,14-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223044
(CHEMBL436340)Show SMILES C[C@H]1CC[C@H](C)N1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@@H](C2)N(C)C)cc1 Show InChI InChI=1S/C28H39N3O2/c1-21-6-7-22(2)31(21)28(32)25-10-8-23(9-11-25)24-12-14-27(15-13-24)33-19-5-17-30-18-16-26(20-30)29(3)4/h8-15,21-22,26H,5-7,16-20H2,1-4H3/t21-,22-,26-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223047
(CHEMBL24847)Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C24H30N2O4/c27-24(26-13-18-29-19-14-26)22-4-2-20(3-5-22)21-6-8-23(9-7-21)30-15-1-10-25-11-16-28-17-12-25/h2-9H,1,10-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222957
(CHEMBL2113223)Show SMILES CN(C)[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCCC2)C1 Show InChI InChI=1S/C26H35N3O2/c1-27(2)24-14-18-28(20-24)15-5-19-31-25-12-10-22(11-13-25)21-6-8-23(9-7-21)26(30)29-16-3-4-17-29/h6-13,24H,3-5,14-20H2,1-2H3/t24-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222961
(CHEMBL27835)Show SMILES CC1CCCN1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@@H](C2)N(C)C)cc1 Show InChI InChI=1S/C27H37N3O2/c1-21-6-4-17-30(21)27(31)24-9-7-22(8-10-24)23-11-13-26(14-12-23)32-19-5-16-29-18-15-25(20-29)28(2)3/h7-14,21,25H,4-6,15-20H2,1-3H3/t21?,25-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222970
(CHEMBL27115)Show SMILES CC1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCC(C)CC2)CC1 Show InChI InChI=1S/C28H38N2O2/c1-22-12-17-29(18-13-22)16-3-21-32-27-10-8-25(9-11-27)24-4-6-26(7-5-24)28(31)30-19-14-23(2)15-20-30/h4-11,22-23H,3,12-21H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222966
(CHEMBL27545)Show SMILES CC1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-21-11-14-28(15-12-21)26(29)24-5-3-22(4-6-24)23-7-9-25(10-8-23)31-18-2-13-27-16-19-30-20-17-27/h3-10,21H,2,11-20H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222972
(CHEMBL28271)Show SMILES CC1CCCN1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C25H32N2O3/c1-20-4-2-14-27(20)25(28)23-7-5-21(6-8-23)22-9-11-24(12-10-22)30-17-3-13-26-15-18-29-19-16-26/h5-12,20H,2-4,13-19H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223037
(CHEMBL25501)Show SMILES CC1CCCN1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C25H32N2O3/c1-19-4-2-15-27(19)25(29)22-7-5-20(6-8-22)21-9-11-24(12-10-21)30-17-3-14-26-16-13-23(28)18-26/h5-12,19,23,28H,2-4,13-18H2,1H3/t19?,23-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222965
(CHEMBL2113222)Show SMILES CN(C)[C@@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 Show InChI InChI=1S/C26H35N3O3/c1-27(2)24-12-14-28(20-24)13-3-17-32-25-10-8-22(9-11-25)21-4-6-23(7-5-21)26(30)29-15-18-31-19-16-29/h4-11,24H,3,12-20H2,1-2H3/t24-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222946
(CHEMBL280895)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@@H](C2)N(C)C)cc1 Show InChI InChI=1S/C26H37N3O2/c1-5-29(6-2)26(30)23-10-8-21(9-11-23)22-12-14-25(15-13-22)31-19-7-17-28-18-16-24(20-28)27(3)4/h8-15,24H,5-7,16-20H2,1-4H3/t24-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222940
(CHEMBL282685)Show SMILES CC(C)N(C)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C24H32N2O3/c1-18(2)25(3)24(28)21-7-5-19(6-8-21)20-9-11-23(12-10-20)29-16-4-14-26-15-13-22(27)17-26/h5-12,18,22,27H,4,13-17H2,1-3H3/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222959
(CHEMBL2113224)Show SMILES CC1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](C2)N(C)C)cc1 Show InChI InChI=1S/C28H39N3O2/c1-22-13-18-31(19-14-22)28(32)25-7-5-23(6-8-25)24-9-11-27(12-10-24)33-20-4-16-30-17-15-26(21-30)29(2)3/h5-12,22,26H,4,13-21H2,1-3H3/t26-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222954
(CHEMBL24865)Show SMILES CC1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-20-11-16-28(17-12-20)26(30)23-5-3-21(4-6-23)22-7-9-25(10-8-22)31-18-2-14-27-15-13-24(29)19-27/h3-10,20,24,29H,2,11-19H2,1H3/t24-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222967
(CHEMBL24198)Show SMILES O[C@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 Show InChI InChI=1S/C24H30N2O4/c27-22-10-12-25(18-22)11-1-15-30-23-8-6-20(7-9-23)19-2-4-21(5-3-19)24(28)26-13-16-29-17-14-26/h2-9,22,27H,1,10-18H2/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222974
(CHEMBL24126)Show SMILES CC(C)NCCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H30N2O3/c1-18(2)24-12-3-15-28-22-10-8-20(9-11-22)19-4-6-21(7-5-19)23(26)25-13-16-27-17-14-25/h4-11,18,24H,3,12-17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222958
(CHEMBL27339)Show SMILES O[C@H]1CCN(CCCOc2ccc(cc2)-c2ccc(cc2)C(=O)N2CCCC2)C1 Show InChI InChI=1S/C24H30N2O3/c27-22-12-16-25(18-22)13-3-17-29-23-10-8-20(9-11-23)19-4-6-21(7-5-19)24(28)26-14-1-2-15-26/h4-11,22,27H,1-3,12-18H2/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222962
(CHEMBL25126)Show SMILES C[C@H]1CC[C@H](C)N1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)26(29)24-8-6-22(7-9-24)23-10-12-25(13-11-23)31-17-3-14-27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222955
(CHEMBL27343)Show SMILES CC(C)NC(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C23H30N2O3/c1-18(2)24-23(26)21-6-4-19(5-7-21)20-8-10-22(11-9-20)28-15-3-12-25-13-16-27-17-14-25/h4-11,18H,3,12-17H2,1-2H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50222953
(CHEMBL281287)Show SMILES O=C(N1CCCC1)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C24H30N2O3/c27-24(26-13-1-2-14-26)22-6-4-20(5-7-22)21-8-10-23(11-9-21)29-17-3-12-25-15-18-28-19-16-25/h4-11H,1-3,12-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50217101
(CHEMBL25688)Show InChI InChI=1S/C20H22N2O/c21-16-17-4-6-18(7-5-17)19-8-10-20(11-9-19)23-15-3-14-22-12-1-2-13-22/h4-11H,1-3,12-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222949
(CHEMBL282062)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C24H32N2O3/c1-3-26(4-2)24(28)21-8-6-19(7-9-21)20-10-12-23(13-11-20)29-17-5-15-25-16-14-22(27)18-25/h6-13,22,27H,3-5,14-18H2,1-2H3/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222947
(CHEMBL24921)Show SMILES CC(C)NCCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCC1C Show InChI InChI=1S/C24H32N2O2/c1-18(2)25-15-5-17-28-23-13-11-21(12-14-23)20-7-9-22(10-8-20)24(27)26-16-4-6-19(26)3/h7-14,18-19,25H,4-6,15-17H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223047
(CHEMBL24847)Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C24H30N2O4/c27-24(26-13-18-29-19-14-26)22-4-2-20(3-5-22)21-6-8-23(9-7-21)30-15-1-10-25-11-16-28-17-12-25/h2-9H,1,10-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222971
(CHEMBL282016)Show SMILES C[C@H]1CC[C@H](C)N1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CC[C@H](O)C2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-19-4-5-20(2)28(19)26(30)23-8-6-21(7-9-23)22-10-12-25(13-11-22)31-17-3-15-27-16-14-24(29)18-27/h6-13,19-20,24,29H,3-5,14-18H2,1-2H3/t19-,20-,24-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222966
(CHEMBL27545)Show SMILES CC1CCN(CC1)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-21-11-14-28(15-12-21)26(29)24-5-3-22(4-6-24)23-7-9-25(10-8-23)31-18-2-13-27-16-19-30-20-17-27/h3-10,21H,2,11-20H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222956
(CHEMBL24352)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C24H32N2O3/c1-3-26(4-2)24(27)22-8-6-20(7-9-22)21-10-12-23(13-11-21)29-17-5-14-25-15-18-28-19-16-25/h6-13H,3-5,14-19H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223049
(CHEMBL284320)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCNC(C)C)cc1 Show InChI InChI=1S/C23H32N2O2/c1-5-25(6-2)23(26)21-10-8-19(9-11-21)20-12-14-22(15-13-20)27-17-7-16-24-18(3)4/h8-15,18,24H,5-7,16-17H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222972
(CHEMBL28271)Show SMILES CC1CCCN1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C25H32N2O3/c1-20-4-2-14-27(20)25(28)23-7-5-21(6-8-23)22-9-11-24(12-10-22)30-17-3-13-26-15-18-29-19-16-26/h5-12,20H,2-4,13-19H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 112 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222962
(CHEMBL25126)Show SMILES C[C@H]1CC[C@H](C)N1C(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)26(29)24-8-6-22(7-9-24)23-10-12-25(13-11-23)31-17-3-14-27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222974
(CHEMBL24126)Show SMILES CC(C)NCCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C23H30N2O3/c1-18(2)24-12-3-15-28-22-10-8-20(9-11-22)19-4-6-21(7-5-19)23(26)25-13-16-27-17-14-25/h4-11,18,24H,3,12-17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| PubMed
| 129 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222955
(CHEMBL27343)Show SMILES CC(C)NC(=O)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C23H30N2O3/c1-18(2)24-23(26)21-6-4-19(5-7-21)20-8-10-22(11-9-20)28-15-3-12-25-13-16-27-17-14-25/h4-11,18H,3,12-17H2,1-2H3,(H,24,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 135 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50222953
(CHEMBL281287)Show SMILES O=C(N1CCCC1)c1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1 Show InChI InChI=1S/C24H30N2O3/c27-24(26-13-1-2-14-26)22-6-4-20(5-7-22)21-8-10-23(11-9-21)29-17-3-12-25-15-18-28-19-16-25/h4-11H,1-3,12-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 178 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223045
(CHEMBL283451)Show SMILES CC(C)NCCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCC(C)CC1 Show InChI InChI=1S/C25H34N2O2/c1-19(2)26-15-4-18-29-24-11-9-22(10-12-24)21-5-7-23(8-6-21)25(28)27-16-13-20(3)14-17-27/h5-12,19-20,26H,4,13-18H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 182 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223046
(CHEMBL25290)Show SMILES CC(C)NCCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1[C@@H](C)CC[C@@H]1C Show InChI InChI=1S/C25H34N2O2/c1-18(2)26-16-5-17-29-24-14-12-22(13-15-24)21-8-10-23(11-9-21)25(28)27-19(3)6-7-20(27)4/h8-15,18-20,26H,5-7,16-17H2,1-4H3/t19-,20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 219 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50223046
(CHEMBL25290)Show SMILES CC(C)NCCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1[C@@H](C)CC[C@@H]1C Show InChI InChI=1S/C25H34N2O2/c1-18(2)26-16-5-17-29-24-14-12-22(13-15-24)21-8-10-23(11-9-21)25(28)27-19(3)6-7-20(27)4/h8-15,18-20,26H,5-7,16-17H2,1-4H3/t19-,20-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 229 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for human recombinant H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223049
(CHEMBL284320)Show SMILES CCN(CC)C(=O)c1ccc(cc1)-c1ccc(OCCCNC(C)C)cc1 Show InChI InChI=1S/C23H32N2O2/c1-5-25(6-2)23(26)21-10-8-19(9-11-21)20-12-14-22(15-13-20)27-17-7-16-24-18(3)4/h8-15,18,24H,5-7,16-17H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 407 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50223045
(CHEMBL283451)Show SMILES CC(C)NCCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCC(C)CC1 Show InChI InChI=1S/C25H34N2O2/c1-19(2)26-15-4-18-29-24-11-9-22(10-12-24)21-5-7-23(8-6-21)25(28)27-16-13-20(3)14-17-27/h5-12,19-20,26H,4,13-18H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 479 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards rat cortical H3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 933 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human muscarinic M2 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human muscarinic M1 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human Alpha-2C adrenergic receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human muscarinic M3 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50222973
(CHEMBL26880)Show SMILES O=C(N1CCCC1)c1ccc(cc1)-c1ccc(OCCCN2CCCC2)cc1 Show InChI InChI=1S/C24H30N2O2/c27-24(26-17-3-4-18-26)22-8-6-20(7-9-22)21-10-12-23(13-11-21)28-19-5-16-25-14-1-2-15-25/h6-13H,1-5,14-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| <1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human histamine (H2) receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50222973
(CHEMBL26880)Show SMILES O=C(N1CCCC1)c1ccc(cc1)-c1ccc(OCCCN2CCCC2)cc1 Show InChI InChI=1S/C24H30N2O2/c27-24(26-17-3-4-18-26)22-8-6-20(7-9-22)21-10-12-23(13-11-21)28-19-5-16-25-14-1-2-15-25/h6-13H,1-5,14-19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| <1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human histamine (H1) receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human histaminergic (H1) receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 3.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human UPTK-Serotonin transporter |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human UPTK-DA transporter |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 9.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human UPTK-NE transporter |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 9.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human D4.2 receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human histaminergic (H4) receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50370569
(A-349,821 | A-349821)Show SMILES C[C@H]1CC[C@H](C)N1CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards human histaminergic (H2) receptor |
Bioorg Med Chem Lett 13: 1325-8 (2003)
BindingDB Entry DOI: 10.7270/Q2HM59NM |
More data for this Ligand-Target Pair | |