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PubMed code 12668010

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor prolyl hydroxylase 1


(Homo sapiens (Human))
BDBM50126536
PNG
((1-Hydroxy-2,5-dioxo-pyrrolidin-3-yl)-acetic acid ...)
Show SMILES ON1C(=O)CC(CC(O)=O)C1=O
Show InChI InChI=1S/C6H7NO5/c8-4-1-3(2-5(9)10)6(11)7(4)12/h3,12H,1-2H2,(H,9,10)
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PubMed
n/an/a 1.00E+6n/an/an/an/an/an/a



Oxford Centre for Molecular Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against purified fusion of maltose binding with PHD1 as enzyme and (HIF) human prolyl hydroxylases as substrate


Bioorg Med Chem Lett 13: 1451-4 (2003)


BindingDB Entry DOI: 10.7270/Q2ZP45HH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%