Affinity Data by PubMed id=12723951

PubMed code 12723951

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50127511 (4-hydroxy-2-(methoxymethyl)-5-(6-oxo-1-prop-2-ynyl...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22.3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.				J Med Chem 46: 1878-85 (2003) Article DOI: 10.1021/jm0203276 BindingDB Entry DOI: 10.7270/Q25X29NG
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50127517 (O-[5-(1-allyl-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-m...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.				J Med Chem 46: 1878-85 (2003) Article DOI: 10.1021/jm0203276 BindingDB Entry DOI: 10.7270/Q25X29NG
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50127514 (4-methoxy-2-(methoxymethyl)-5-(6-oxo-1-prop-2-ynyl...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.				J Med Chem 46: 1878-85 (2003) Article DOI: 10.1021/jm0203276 BindingDB Entry DOI: 10.7270/Q25X29NG
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50127512 ((2R,3S,5R)-4-methoxy-2-(methoxymethyl)-5-(1-propyl...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.				J Med Chem 46: 1878-85 (2003) Article DOI: 10.1021/jm0203276 BindingDB Entry DOI: 10.7270/Q25X29NG
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50127513 ((2R,3S,5R)-4-methoxy-2-(methoxymethyl)-5-(6-oxo-1-...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.				J Med Chem 46: 1878-85 (2003) Article DOI: 10.1021/jm0203276 BindingDB Entry DOI: 10.7270/Q25X29NG
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50127515 (5-(1-allyl-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydr...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.				J Med Chem 46: 1878-85 (2003) Article DOI: 10.1021/jm0203276 BindingDB Entry DOI: 10.7270/Q25X29NG
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50127516 (5-(1-allyl-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-meth...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Curated by ChEMBL					Assay Description Inhibitory activity of compound against reverse transcriptase (RT) in cell free RT.				J Med Chem 46: 1878-85 (2003) Article DOI: 10.1021/jm0203276 BindingDB Entry DOI: 10.7270/Q25X29NG
University of Utah Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%