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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acetylcholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 20.5 | -45.6 | 23.1 | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Bologna | Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob... | J Med Chem 46: 2279-82 (2003) Article DOI: 10.1021/jm0340602 BindingDB Entry DOI: 10.7270/Q29Z9332 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Acetylcholinesterase (Homo sapiens (Human)) | BDBM10949 (3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 21.7 | -45.5 | 44.5 | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Bologna | Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob... | J Med Chem 46: 2279-82 (2003) Article DOI: 10.1021/jm0340602 BindingDB Entry DOI: 10.7270/Q29Z9332 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.42E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Bologna | Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob... | J Med Chem 46: 2279-82 (2003) Article DOI: 10.1021/jm0340602 BindingDB Entry DOI: 10.7270/Q29Z9332 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cholinesterase (Homo sapiens (Human)) | BDBM10949 (3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.89E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 |
University of Bologna | Assay Description The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob... | J Med Chem 46: 2279-82 (2003) Article DOI: 10.1021/jm0340602 BindingDB Entry DOI: 10.7270/Q29Z9332 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
