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PubMed code 12798333

Compile data set for download or QSAR
Found 56 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065124
PNG
(CHEMBL68085 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H22FN3O2/c1-18-8-11-21(28)15-24(18)26(32)29-22-12-9-19(10-13-22)27(33)31-17-23-6-4-14-30(23)16-20-5-2-3-7-25(20)31/h2-15H,16-17H2,1H3,(H,29,32)
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n/an/a 1.5n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129464
PNG
(CHEMBL71355 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Brc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H20BrN3O2/c27-23-9-3-2-8-22(23)25(31)28-20-13-11-18(12-14-20)26(32)30-17-21-7-5-15-29(21)16-19-6-1-4-10-24(19)30/h1-15H,16-17H2,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065115
PNG
(3-chloro-4-(10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a...)
Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1
Show InChI InChI=1S/C27H21ClFN3O2/c1-17-8-9-19(29)13-23(17)26(33)30-20-10-11-22(24(28)14-20)27(34)32-16-21-6-4-12-31(21)15-18-5-2-3-7-25(18)32/h2-14H,15-16H2,1H3,(H,30,33)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065110
PNG
(CHEMBL418890 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1
Show InChI InChI=1S/C26H19Cl2N3O2/c27-19-9-12-22(23(28)14-19)25(32)29-20-10-7-17(8-11-20)26(33)31-16-21-5-3-13-30(21)15-18-4-1-2-6-24(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065127
PNG
(CHEMBL71797 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H23N3O2/c1-19-7-2-4-10-24(19)26(31)28-22-14-12-20(13-15-22)27(32)30-18-23-9-6-16-29(23)17-21-8-3-5-11-25(21)30/h2-16H,17-18H2,1H3,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065122
PNG
(CHEMBL306970 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Fc1ccc(C(=O)Nc2ccc(cc2)C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1
Show InChI InChI=1S/C26H19ClFN3O2/c27-23-14-19(28)9-12-22(23)25(32)29-20-10-7-17(8-11-20)26(33)31-16-21-5-3-13-30(21)15-18-4-1-2-6-24(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065119
PNG
(CHEMBL70981 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Cc1c(F)cccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H22FN3O2/c1-18-23(8-4-9-24(18)28)26(32)29-21-13-11-19(12-14-21)27(33)31-17-22-7-5-15-30(22)16-20-6-2-3-10-25(20)31/h2-15H,16-17H2,1H3,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065120
PNG
(CHEMBL302709 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H20ClN3O2/c27-23-9-3-2-8-22(23)25(31)28-20-13-11-18(12-14-20)26(32)30-17-21-7-5-15-29(21)16-19-6-1-4-10-24(19)30/h1-15H,16-17H2,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065122
PNG
(CHEMBL306970 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Fc1ccc(C(=O)Nc2ccc(cc2)C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1
Show InChI InChI=1S/C26H19ClFN3O2/c27-23-14-19(28)9-12-22(23)25(32)29-20-10-7-17(8-11-20)26(33)31-16-21-5-3-13-30(21)15-18-4-1-2-6-24(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129464
PNG
(CHEMBL71355 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Brc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H20BrN3O2/c27-23-9-3-2-8-22(23)25(31)28-20-13-11-18(12-14-20)26(32)30-17-21-7-5-15-29(21)16-19-6-1-4-10-24(19)30/h1-15H,16-17H2,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129469
PNG
(CHEMBL304060 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES CSc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H23N3O2S/c1-33-25-11-5-3-9-23(25)26(31)28-21-14-12-19(13-15-21)27(32)30-18-22-8-6-16-29(22)17-20-7-2-4-10-24(20)30/h2-16H,17-18H2,1H3,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065120
PNG
(CHEMBL302709 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Clc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H20ClN3O2/c27-23-9-3-2-8-22(23)25(31)28-20-13-11-18(12-14-20)26(32)30-17-21-7-5-15-29(21)16-19-6-1-4-10-24(19)30/h1-15H,16-17H2,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129469
PNG
(CHEMBL304060 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES CSc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H23N3O2S/c1-33-25-11-5-3-9-23(25)26(31)28-21-14-12-19(13-15-21)27(32)30-18-22-8-6-16-29(22)17-20-7-2-4-10-24(20)30/h2-16H,17-18H2,1H3,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065117
PNG
(CHEMBL304956 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Cc1cccc(C(=O)Nc2ccc(cc2)C(=O)N2Cc3cccn3Cc3ccccc23)c1C
Show InChI InChI=1S/C28H25N3O2/c1-19-7-5-10-25(20(19)2)27(32)29-23-14-12-21(13-15-23)28(33)31-18-24-9-6-16-30(24)17-22-8-3-4-11-26(22)31/h3-16H,17-18H2,1-2H3,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129475
PNG
(CHEMBL68948 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Clc1ccc(Cl)c(c1)C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H19Cl2N3O2/c27-19-9-12-23(28)22(14-19)25(32)29-20-10-7-17(8-11-20)26(33)31-16-21-5-3-13-30(21)15-18-4-1-2-6-24(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065126
PNG
(CHEMBL73286 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES COc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H23N3O3/c1-33-25-11-5-3-9-23(25)26(31)28-21-14-12-19(13-15-21)27(32)30-18-22-8-6-16-29(22)17-20-7-2-4-10-24(20)30/h2-16H,17-18H2,1H3,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129468
PNG
(CHEMBL302955 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H19Cl2N3O2/c27-21-7-3-8-22(28)24(21)25(32)29-19-12-10-17(11-13-19)26(33)31-16-20-6-4-14-30(20)15-18-5-1-2-9-23(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129472
PNG
(CHEMBL70949 | N-[4-(5,11-Dihydro-dibenzo[b,e][1,4]...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Nc2ccccc12
Show InChI InChI=1S/C28H23N3O2/c1-19-8-2-4-10-23(19)27(32)29-22-16-14-20(15-17-22)28(33)31-18-21-9-3-5-11-24(21)30-25-12-6-7-13-26(25)31/h2-17,30H,18H2,1H3,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065124
PNG
(CHEMBL68085 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H22FN3O2/c1-18-8-11-21(28)15-24(18)26(32)29-22-12-9-19(10-13-22)27(33)31-17-23-6-4-14-30(23)16-20-5-2-3-7-25(20)31/h2-15H,16-17H2,1H3,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50065130
PNG
(CHEMBL71305 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES FC(F)(F)c1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H20F3N3O2/c28-27(29,30)23-9-3-2-8-22(23)25(34)31-20-13-11-18(12-14-20)26(35)33-17-21-7-5-15-32(21)16-19-6-1-4-10-24(19)33/h1-15H,16-17H2,(H,31,34)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065110
PNG
(CHEMBL418890 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Clc1ccc(C(=O)Nc2ccc(cc2)C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1
Show InChI InChI=1S/C26H19Cl2N3O2/c27-19-9-12-22(23(28)14-19)25(32)29-20-10-7-17(8-11-20)26(33)31-16-21-5-3-13-30(21)15-18-4-1-2-6-24(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129460
PNG
(CHEMBL308741 | N-[4-(6,7-Dihydro-dibenzo[b,d]azepi...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCc2ccccc2-c2ccccc12
Show InChI InChI=1S/C29H24N2O2/c1-20-8-2-4-10-24(20)28(32)30-23-16-14-22(15-17-23)29(33)31-19-18-21-9-3-5-11-25(21)26-12-6-7-13-27(26)31/h2-17H,18-19H2,1H3,(H,30,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065119
PNG
(CHEMBL70981 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Cc1c(F)cccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H22FN3O2/c1-18-23(8-4-9-24(18)28)26(32)29-21-13-11-19(12-14-21)27(33)31-17-22-7-5-15-30(22)16-20-6-2-3-10-25(20)31/h2-15H,16-17H2,1H3,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065130
PNG
(CHEMBL71305 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES FC(F)(F)c1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H20F3N3O2/c28-27(29,30)23-9-3-2-8-22(23)25(34)31-20-13-11-18(12-14-20)26(35)33-17-21-7-5-15-32(21)16-19-6-1-4-10-24(19)33/h1-15H,16-17H2,(H,31,34)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129463
PNG
(CHEMBL71282 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Clc1cccc(C(=O)Nc2ccc(cc2)C(=O)N2Cc3cccn3Cc3ccccc23)c1Cl
Show InChI InChI=1S/C26H19Cl2N3O2/c27-22-8-3-7-21(24(22)28)25(32)29-19-12-10-17(11-13-19)26(33)31-16-20-6-4-14-30(20)15-18-5-1-2-9-23(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129476
PNG
(2-Methyl-N-[4-(6H-phenanthridine-5-carbonyl)-pheny...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2-c2ccccc12
Show InChI InChI=1S/C28H22N2O2/c1-19-8-2-4-10-23(19)27(31)29-22-16-14-20(15-17-22)28(32)30-18-21-9-3-5-11-24(21)25-12-6-7-13-26(25)30/h2-17H,18H2,1H3,(H,29,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129463
PNG
(CHEMBL71282 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Clc1cccc(C(=O)Nc2ccc(cc2)C(=O)N2Cc3cccn3Cc3ccccc23)c1Cl
Show InChI InChI=1S/C26H19Cl2N3O2/c27-22-8-3-7-21(24(22)28)25(32)29-19-12-10-17(11-13-19)26(33)31-16-20-6-4-14-30(20)15-18-5-1-2-9-23(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065126
PNG
(CHEMBL73286 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES COc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H23N3O3/c1-33-25-11-5-3-9-23(25)26(31)28-21-14-12-19(13-15-21)27(32)30-18-22-8-6-16-29(22)17-20-7-2-4-10-24(20)30/h2-16H,17-18H2,1H3,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129461
PNG
(CHEMBL303176 | N-[4-(4,5-Dihydro-benzo[b]pyrrolo[1...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCc2cccn2-c2ccccc12
Show InChI InChI=1S/C27H23N3O2/c1-19-7-2-3-9-23(19)26(31)28-21-14-12-20(13-15-21)27(32)30-18-16-22-8-6-17-29(22)24-10-4-5-11-25(24)30/h2-15,17H,16,18H2,1H3,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129466
PNG
(CHEMBL442743 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Fc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H20FN3O2/c27-23-9-3-2-8-22(23)25(31)28-20-13-11-18(12-14-20)26(32)30-17-21-7-5-15-29(21)16-19-6-1-4-10-24(19)30/h1-15H,16-17H2,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065127
PNG
(CHEMBL71797 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C27H23N3O2/c1-19-7-2-4-10-24(19)26(31)28-22-14-12-20(13-15-22)27(32)30-18-23-9-6-16-29(23)17-21-8-3-5-11-25(21)30/h2-16H,17-18H2,1H3,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129472
PNG
(CHEMBL70949 | N-[4-(5,11-Dihydro-dibenzo[b,e][1,4]...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Nc2ccccc12
Show InChI InChI=1S/C28H23N3O2/c1-19-8-2-4-10-23(19)27(32)29-22-16-14-20(15-17-22)28(33)31-18-21-9-3-5-11-24(21)30-25-12-6-7-13-26(25)31/h2-17,30H,18H2,1H3,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129465
PNG
(CHEMBL309096 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES CCOc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C28H25N3O3/c1-2-34-26-12-6-4-10-24(26)27(32)29-22-15-13-20(14-16-22)28(33)31-19-23-9-7-17-30(23)18-21-8-3-5-11-25(21)31/h3-17H,2,18-19H2,1H3,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129476
PNG
(2-Methyl-N-[4-(6H-phenanthridine-5-carbonyl)-pheny...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2-c2ccccc12
Show InChI InChI=1S/C28H22N2O2/c1-19-8-2-4-10-23(19)27(31)29-22-16-14-20(15-17-22)28(32)30-18-21-9-3-5-11-24(21)25-12-6-7-13-26(25)30/h2-17H,18H2,1H3,(H,29,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129466
PNG
(CHEMBL442743 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Fc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H20FN3O2/c27-23-9-3-2-8-22(23)25(31)28-20-13-11-18(12-14-20)26(32)30-17-21-7-5-15-29(21)16-19-6-1-4-10-24(19)30/h1-15H,16-17H2,(H,28,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129477
PNG
(2-Methyl-N-[4-(4H-pyrrolo[1,2-a]quinoxaline-5-carb...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2-c2ccccc12
Show InChI InChI=1S/C26H21N3O2/c1-18-7-2-3-9-22(18)25(30)27-20-14-12-19(13-15-20)26(31)29-17-21-8-6-16-28(21)23-10-4-5-11-24(23)29/h2-16H,17H2,1H3,(H,27,30)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129473
PNG
(CHEMBL307271 | N-[4-(6,11-Dihydro-dibenzo[b,e]azep...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Cc2ccccc12
Show InChI InChI=1S/C29H24N2O2/c1-20-8-2-6-12-26(20)28(32)30-25-16-14-21(15-17-25)29(33)31-19-24-11-4-3-9-22(24)18-23-10-5-7-13-27(23)31/h2-17H,18-19H2,1H3,(H,30,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129465
PNG
(CHEMBL309096 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES CCOc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C28H25N3O3/c1-2-34-26-12-6-4-10-24(26)27(32)29-22-15-13-20(14-16-22)28(33)31-19-23-9-7-17-30(23)18-21-8-3-5-11-25(21)31/h3-17H,2,18-19H2,1H3,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129467
PNG
(CHEMBL72342 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Oc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H21N3O3/c30-24-10-4-2-8-22(24)25(31)27-20-13-11-18(12-14-20)26(32)29-17-21-7-5-15-28(21)16-19-6-1-3-9-23(19)29/h1-15,30H,16-17H2,(H,27,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129468
PNG
(CHEMBL302955 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Clc1cccc(Cl)c1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H19Cl2N3O2/c27-21-7-3-8-22(28)24(21)25(32)29-19-12-10-17(11-13-19)26(33)31-16-20-6-4-14-30(20)15-18-5-1-2-9-23(18)31/h1-14H,15-16H2,(H,29,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129460
PNG
(CHEMBL308741 | N-[4-(6,7-Dihydro-dibenzo[b,d]azepi...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCc2ccccc2-c2ccccc12
Show InChI InChI=1S/C29H24N2O2/c1-20-8-2-4-10-24(20)28(32)30-23-16-14-22(15-17-23)29(33)31-19-18-21-9-3-5-11-25(21)26-12-6-7-13-27(26)31/h2-17H,18-19H2,1H3,(H,30,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129475
PNG
(CHEMBL68948 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Clc1ccc(Cl)c(c1)C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H19Cl2N3O2/c27-19-9-12-23(28)22(14-19)25(32)29-20-10-7-17(8-11-20)26(33)31-16-21-5-3-13-30(21)15-18-4-1-2-6-24(18)31/h1-14H,15-16H2,(H,29,32)
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n/an/a 120n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129473
PNG
(CHEMBL307271 | N-[4-(6,11-Dihydro-dibenzo[b,e]azep...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Cc2ccccc12
Show InChI InChI=1S/C29H24N2O2/c1-20-8-2-6-12-26(20)28(32)30-25-16-14-21(15-17-25)29(33)31-19-24-11-4-3-9-22(24)18-23-10-5-7-13-27(23)31/h2-17H,18-19H2,1H3,(H,30,32)
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n/an/a 150n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129477
PNG
(2-Methyl-N-[4-(4H-pyrrolo[1,2-a]quinoxaline-5-carb...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2-c2ccccc12
Show InChI InChI=1S/C26H21N3O2/c1-18-7-2-3-9-22(18)25(30)27-20-14-12-19(13-15-20)26(31)29-17-21-8-6-16-28(21)23-10-4-5-11-24(23)29/h2-16H,17H2,1H3,(H,27,30)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065117
PNG
(CHEMBL304956 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a]...)
Show SMILES Cc1cccc(C(=O)Nc2ccc(cc2)C(=O)N2Cc3cccn3Cc3ccccc23)c1C
Show InChI InChI=1S/C28H25N3O2/c1-19-7-5-10-25(20(19)2)27(32)29-23-14-12-21(13-15-23)28(33)31-18-24-9-6-16-30(24)17-22-8-3-4-11-26(22)31/h3-16H,17-18H2,1-2H3,(H,29,32)
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n/an/a 240n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129461
PNG
(CHEMBL303176 | N-[4-(4,5-Dihydro-benzo[b]pyrrolo[1...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCc2cccn2-c2ccccc12
Show InChI InChI=1S/C27H23N3O2/c1-19-7-2-3-9-23(19)26(31)28-21-14-12-20(13-15-21)27(32)30-18-16-22-8-6-17-29(22)24-10-4-5-11-25(24)30/h2-15,17H,16,18H2,1H3,(H,28,31)
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n/an/a 270n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129471
PNG
(CHEMBL71712 | N-[4-(11H-Dibenzo[b,f][1,4]thiazepin...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Sc2ccccc12
Show InChI InChI=1S/C28H22N2O2S/c1-19-8-2-4-10-23(19)27(31)29-22-16-14-20(15-17-22)28(32)30-18-21-9-3-6-12-25(21)33-26-13-7-5-11-24(26)30/h2-17H,18H2,1H3,(H,29,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50065115
PNG
(3-chloro-4-(10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a...)
Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1
Show InChI InChI=1S/C27H21ClFN3O2/c1-17-8-9-19(29)13-23(17)26(33)30-20-10-11-22(24(28)14-20)27(34)32-16-21-6-4-12-31(21)15-18-5-2-3-7-25(18)32/h2-14H,15-16H2,1H3,(H,30,33)
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n/an/a 410n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129467
PNG
(CHEMBL72342 | N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][...)
Show SMILES Oc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2cccn2Cc2ccccc12
Show InChI InChI=1S/C26H21N3O3/c30-24-10-4-2-8-22(24)25(31)27-20-13-11-18(12-14-20)26(32)29-17-21-7-5-15-28(21)16-19-6-1-3-9-23(19)29/h1-15,30H,16-17H2,(H,27,31)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129471
PNG
(CHEMBL71712 | N-[4-(11H-Dibenzo[b,f][1,4]thiazepin...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Sc2ccccc12
Show InChI InChI=1S/C28H22N2O2S/c1-19-8-2-4-10-23(19)27(31)29-22-16-14-20(15-17-22)28(32)30-18-21-9-3-6-12-25(21)33-26-13-7-5-11-24(26)30/h2-17H,18H2,1H3,(H,29,31)
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n/an/a 860n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129462
PNG
(CHEMBL303376 | N-[4-(10,11-Dihydro-dibenzo[b,f]aze...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C29H24N2O2/c1-20-8-2-5-11-25(20)28(32)30-24-18-16-23(17-19-24)29(33)31-26-12-6-3-9-21(26)14-15-22-10-4-7-13-27(22)31/h2-13,16-19H,14-15H2,1H3,(H,30,32)
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Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129470
PNG
(CHEMBL71283 | N-[4-(11H-Dibenzo[b,f][1,4]oxazepine...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Oc2ccccc12
Show InChI InChI=1S/C28H22N2O3/c1-19-8-2-4-10-23(19)27(31)29-22-16-14-20(15-17-22)28(32)30-18-21-9-3-6-12-25(21)33-26-13-7-5-11-24(26)30/h2-17H,18H2,1H3,(H,29,31)
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n/an/a 1.50E+3n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129470
PNG
(CHEMBL71283 | N-[4-(11H-Dibenzo[b,f][1,4]oxazepine...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Oc2ccccc12
Show InChI InChI=1S/C28H22N2O3/c1-19-8-2-4-10-23(19)27(31)29-22-16-14-20(15-17-22)28(32)30-18-21-9-3-6-12-25(21)33-26-13-7-5-11-24(26)30/h2-17H,18H2,1H3,(H,29,31)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129462
PNG
(CHEMBL303376 | N-[4-(10,11-Dihydro-dibenzo[b,f]aze...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1c2ccccc2CCc2ccccc12
Show InChI InChI=1S/C29H24N2O2/c1-20-8-2-5-11-25(20)28(32)30-24-18-16-23(17-19-24)29(33)31-26-12-6-3-9-21(26)14-15-22-10-4-7-13-27(22)31/h2-13,16-19H,14-15H2,1H3,(H,30,32)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat hepatic vasopressin V1a receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V1a receptor


(RAT)		BDBM50129474
PNG
(CHEMBL71626 | N-[4-(11,12-Dihydro-6H-dibenzo[b,f]a...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2CCc2ccccc12
Show InChI InChI=1S/C30H26N2O2/c1-21-8-2-6-12-27(21)29(33)31-26-18-16-24(17-19-26)30(34)32-20-25-11-4-3-9-22(25)14-15-23-10-5-7-13-28(23)32/h2-13,16-19H,14-15,20H2,1H3,(H,31,33)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Compound was tested for the inhibition of [3H]-AVP binding to Dawley rat kidney medullary Vasopressin V1a receptor

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
Vasopressin V2 receptor


(Rattus norvegicus (Rat))		BDBM50129474
PNG
(CHEMBL71626 | N-[4-(11,12-Dihydro-6H-dibenzo[b,f]a...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2CCc2ccccc12
Show InChI InChI=1S/C30H26N2O2/c1-21-8-2-6-12-27(21)29(33)31-26-18-16-24(17-19-26)30(34)32-20-25-11-4-3-9-22(25)14-15-23-10-5-7-13-28(23)32/h2-13,16-19H,14-15,20H2,1H3,(H,31,33)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AVP binding to Dawley rat kidney medullary vasopressin V2 receptor.

Bioorg Med Chem Lett 13: 2195-8 (2003)


BindingDB Entry DOI: 10.7270/Q2SF2VJH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%