Affinity Data by PubMed id=12801228

PubMed code 12801228

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50017478 (Amastatin \| CHEMBL28650 \| Leu[1psi,CHOHCONH]ValVal...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50129681 (3-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards aminopeptidase N (APN) from pig kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129685 (2-Amino-4-methyl-pentanal \| CHEMBL88476) Show SMILES CC(C)CC(N)C=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129684 (3-[(1-amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129681 (3-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129682 (2-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoylme...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CCc1ccccc1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129679 ((1-Amino-3-methyl-butyl)-phosphonic acid \| 1-amino...) Show SMILES CC(C)CC(N)P(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50129684 (3-[(1-amino-3-phenyl-propyl)-hydroxy-phosphinoyl]-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards aminopeptidase N (APN) from pig kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129677 (3-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoyl]-p...) Show SMILES CC(C)CC(=N)P(O)(O)CCC(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50129682 (2-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoylme...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CCc1ccccc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards aminopeptidase N (APN) from pig kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards aminopeptidase N (APN) from pig kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50129677 (3-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoyl]-p...) Show SMILES CC(C)CC(=N)P(O)(O)CCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards aminopeptidase N (APN) from pig kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129680 (CHEMBL423870 \| {[hydroxy(1-hydroxy-3-methylbutyl)p...) Show SMILES CC(C)CC(O)P([O-])(=O)NCC([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50129679 ((1-Amino-3-methyl-butyl)-phosphonic acid \| 1-amino...) Show SMILES CC(C)CC(N)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards aminopeptidase N (APN) from pig kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Homo sapiens (Human))	BDBM50129678 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoyloxy...) Show SMILES CC(C)CC(N)P(O)(=O)OC(CC(C)C)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
Wroclaw University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%