Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50129964 (1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129954 (4-(4-Methyl-7-o-tolyl-quinolin-2-yloxy)-benzamidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129957 (2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129956 (CHEMBL74314 | {3-[2-(4-Carbamimidoyl-phenoxy)-4-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129965 (CHEMBL73043 | {3-[2-(4-Carbamimidoyl-phenoxy)-4-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129967 (2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129958 (3-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129961 (4-(4-Methyl-7-p-tolyl-quinolin-2-yloxy)-benzamidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129953 (4-(4-Methyl-7-o-tolyl-quinolin-2-ylamino)-benzamid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129963 (4-(7-Bromo-4-methyl-quinolin-2-yloxy)-benzamidine ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129966 (4-(7-Bromo-4-methyl-quinolin-2-ylamino)-benzamidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129962 (CHEMBL310265 | [2-(4-Carbamimidoyl-phenoxy)-4-meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129955 (4-(7-Bromo-4-methyl-quinolin-2-ylsulfanyl)-benzami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 196 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50129964 (1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against trypsin | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129959 (3-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50112082 (4-(5-Benzenesulfonylamino-1-methyl-1H-benzoimidazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50129964 (1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against coagulation factor X in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50129957 (2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against trypsin | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50129954 (4-(4-Methyl-7-o-tolyl-quinolin-2-yloxy)-benzamidin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against trypsin | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50129953 (4-(4-Methyl-7-o-tolyl-quinolin-2-ylamino)-benzamid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against trypsin | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50129960 (CHEMBL420747 | [2-(4-Carbamimidoyl-phenoxy)-4-meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description In vitro inhibitory activity against thrombin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50129961 (4-(4-Methyl-7-p-tolyl-quinolin-2-yloxy)-benzamidin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against trypsin | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50129964 (1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against plasmin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50129958 (3-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against plasmin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50129958 (3-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against trypsin | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50129959 (3-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against trypsin | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50129954 (4-(4-Methyl-7-o-tolyl-quinolin-2-yloxy)-benzamidin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against plasmin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50129961 (4-(4-Methyl-7-p-tolyl-quinolin-2-yloxy)-benzamidin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against plasmin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50129953 (4-(4-Methyl-7-o-tolyl-quinolin-2-ylamino)-benzamid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 1.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against plasmin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50129957 (2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against plasmin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50129959 (3-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory activity of the compound against plasmin in human plasma | Bioorg Med Chem Lett 13: 2291-5 (2003) BindingDB Entry DOI: 10.7270/Q2QJ7GP2 | |||||||||||
More data for this Ligand-Target Pair |