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PubMed code 12825934

Compile data set for download or QSAR
Found 55 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM12578
PNG
(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Show SMILES OC(Cn1ccnc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14)
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n/an/a 0.240n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422472
PNG
(CHEMBL100827)
Show SMILES CN(CCCSc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H23NO7P2S/c1-14(9-5-11-24-12-6-3-2-4-7-12)10-8-13(15,22(16,17)18)23(19,20)21/h2-4,6-7,15H,5,8-11H2,1H3,(H2,16,17,18)(H2,19,20,21)
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n/an/a 0.620n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM25290
PNG
(CHEMBL56073 | bisphosphonate, 39 | {1-hydroxy-3-[m...)
Show SMILES CN(CCCCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C14H25NO7P2/c1-15(11-6-5-9-13-7-3-2-4-8-13)12-10-14(16,23(17,18)19)24(20,21)22/h2-4,7-8,16H,5-6,9-12H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 1n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50098389
PNG
(1-hydroxy-2-(1H-imidazol-5-yl)ethane-1,1-diyldipho...)
Show SMILES OC(Cc1cnc[nH]1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)1-4-2-6-3-7-4/h2-3,8H,1H2,(H,6,7)(H2,9,10,11)(H2,12,13,14)
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n/an/a 1.10n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422449
PNG
(CHEMBL101886)
Show SMILES CN(CCCOc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H23NO8P2/c1-14(9-5-11-22-12-6-3-2-4-7-12)10-8-13(15,23(16,17)18)24(19,20)21/h2-4,6-7,15H,5,8-11H2,1H3,(H2,16,17,18)(H2,19,20,21)
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n/an/a 1.30n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422469
PNG
(CHEMBL101472)
Show SMILES CN(CCCOc1ccc(F)cc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H22FNO8P2/c1-15(8-2-10-23-12-5-3-11(14)4-6-12)9-7-13(16,24(17,18)19)25(20,21)22/h3-6,16H,2,7-10H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 1.40n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422457
PNG
(CHEMBL101230)
Show SMILES CN(CCCc1ccc(Cl)cc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H22ClNO7P2/c1-15(9-2-3-11-4-6-12(14)7-5-11)10-8-13(16,23(17,18)19)24(20,21)22/h4-7,16H,2-3,8-10H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 1.70n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422470
PNG
(CHEMBL100508)
Show SMILES CN(CCSc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H21NO7P2S/c1-13(9-10-23-11-5-3-2-4-6-11)8-7-12(14,21(15,16)17)22(18,19)20/h2-6,14H,7-10H2,1H3,(H2,15,16,17)(H2,18,19,20)
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n/an/a 1.80n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422463
PNG
(CHEMBL101207)
Show SMILES Cn1ccnc1CC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H12N2O7P2/c1-8-3-2-7-5(8)4-6(9,16(10,11)12)17(13,14)15/h2-3,9H,4H2,1H3,(H2,10,11,12)(H2,13,14,15)
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n/an/a 2n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50117257
PNG
(1-hydroxy-3-(methyl(3-phenylpropyl)amino)propane-1...)
Show SMILES CN(CCCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H23NO7P2/c1-14(10-5-8-12-6-3-2-4-7-12)11-9-13(15,22(16,17)18)23(19,20)21/h2-4,6-7,15H,5,8-11H2,1H3,(H2,16,17,18)(H2,19,20,21)
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n/an/a 2.60n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422455
PNG
(CHEMBL98476)
Show SMILES CCCCc1cnc(NC(P(O)(O)=O)P(O)(O)=O)s1
Show InChI InChI=1S/C8H16N2O6P2S/c1-2-3-4-6-5-9-7(19-6)10-8(17(11,12)13)18(14,15)16/h5,8H,2-4H2,1H3,(H,9,10)(H2,11,12,13)(H2,14,15,16)
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n/an/a 2.70n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50135839
PNG
(CHEMBL55464 | [1-Hydroxy-3-(4-phenyl-butylamino)-1...)
Show SMILES OC(CCNCCCCc1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H23NO7P2/c15-13(22(16,17)18,23(19,20)21)9-11-14-10-5-4-8-12-6-2-1-3-7-12/h1-3,6-7,14-15H,4-5,8-11H2,(H2,16,17,18)(H2,19,20,21)
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n/an/a 2.70n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422454
PNG
(CHEMBL316913)
Show SMILES COc1ccc(OCCCN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O)cc1
Show InChI InChI=1S/C14H25NO9P2/c1-15(10-8-14(16,25(17,18)19)26(20,21)22)9-3-11-24-13-6-4-12(23-2)5-7-13/h4-7,16H,3,8-11H2,1-2H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 2.80n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422446
PNG
(CHEMBL101407)
Show SMILES CN(CCCOc1ccc(Cl)cc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H22ClNO8P2/c1-15(8-2-10-23-12-5-3-11(14)4-6-12)9-7-13(16,24(17,18)19)25(20,21)22/h3-6,16H,2,7-10H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 3.10n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50135831
PNG
(CHEMBL316844 | [1-Hydroxy-3-(3-phenoxy-propylamino...)
Show SMILES OC(CCNCCCOc1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H21NO8P2/c14-12(22(15,16)17,23(18,19)20)7-9-13-8-4-10-21-11-5-2-1-3-6-11/h1-3,5-6,13-14H,4,7-10H2,(H2,15,16,17)(H2,18,19,20)
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n/an/a 3.30n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422448
PNG
(CHEMBL100441)
Show SMILES CN(CCCc1cccc(C)c1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C14H25NO7P2/c1-12-5-3-6-13(11-12)7-4-9-15(2)10-8-14(16,23(17,18)19)24(20,21)22/h3,5-6,11,16H,4,7-10H2,1-2H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 3.90n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50117260
PNG
(1-hydroxy-3-(methyl(phenethyl)amino)propane-1,1-di...)
Show SMILES CN(CCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H21NO7P2/c1-13(9-7-11-5-3-2-4-6-11)10-8-12(14,21(15,16)17)22(18,19)20/h2-6,14H,7-10H2,1H3,(H2,15,16,17)(H2,18,19,20)
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n/an/a 3.90n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50138041
PNG
(1-hydroxy-3-(methyl(2-phenoxyethyl)amino)propane-1...)
Show SMILES CN(CCOc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H21NO8P2/c1-13(9-10-21-11-5-3-2-4-6-11)8-7-12(14,22(15,16)17)23(18,19)20/h2-6,14H,7-10H2,1H3,(H2,15,16,17)(H2,18,19,20)
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n/an/a 4n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422464
PNG
(CHEMBL319519)
Show SMILES CN(CCOc1ccc(Cl)cc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H20ClNO8P2/c1-14(8-9-22-11-4-2-10(13)3-5-11)7-6-12(15,23(16,17)18)24(19,20)21/h2-5,15H,6-9H2,1H3,(H2,16,17,18)(H2,19,20,21)
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n/an/a 4.10n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422458
PNG
(CHEMBL100835)
Show SMILES CN(CCCOc1cccc(C)c1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C14H25NO8P2/c1-12-5-3-6-13(11-12)23-10-4-8-15(2)9-7-14(16,24(17,18)19)25(20,21)22/h3,5-6,11,16H,4,7-10H2,1-2H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 4.30n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422467
PNG
(CHEMBL100830)
Show SMILES CCc1cnc(NC(P(O)(O)=O)P(O)(O)=O)s1
Show InChI InChI=1S/C6H12N2O6P2S/c1-2-4-3-7-5(17-4)8-6(15(9,10)11)16(12,13)14/h3,6H,2H2,1H3,(H,7,8)(H2,9,10,11)(H2,12,13,14)
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n/an/a 4.80n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422475
PNG
(CHEMBL98703)
Show SMILES Cc1ncn(CC(O)(P(O)(O)=O)P(O)(O)=O)c1C
Show InChI InChI=1S/C7H14N2O7P2/c1-5-6(2)9(4-8-5)3-7(10,17(11,12)13)18(14,15)16/h4,10H,3H2,1-2H3,(H2,11,12,13)(H2,14,15,16)
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n/an/a 5n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422461
PNG
(CHEMBL100335)
Show SMILES Cc1cnc(NC(P(O)(O)=O)P(O)(O)=O)s1
Show InChI InChI=1S/C5H10N2O6P2S/c1-3-2-6-4(16-3)7-5(14(8,9)10)15(11,12)13/h2,5H,1H3,(H,6,7)(H2,8,9,10)(H2,11,12,13)
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n/an/a 5.10n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422477
PNG
(CHEMBL317646)
Show SMILES Cc1nc[nH]c1CC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H12N2O7P2/c1-4-5(8-3-7-4)2-6(9,16(10,11)12)17(13,14)15/h3,9H,2H2,1H3,(H,7,8)(H2,10,11,12)(H2,13,14,15)
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n/an/a 5.10n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422444
PNG
(CHEMBL100295)
Show SMILES CCCc1cnc(NC(P(O)(O)=O)P(O)(O)=O)s1
Show InChI InChI=1S/C7H14N2O6P2S/c1-2-3-5-4-8-6(18-5)9-7(16(10,11)12)17(13,14)15/h4,7H,2-3H2,1H3,(H,8,9)(H2,10,11,12)(H2,13,14,15)
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n/an/a 6.20n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422441
PNG
(CHEMBL101539)
Show SMILES OP(O)(=O)C(Nc1ncc(CCc2ccccc2)s1)P(O)(O)=O
Show InChI InChI=1S/C12H16N2O6P2S/c15-21(16,17)12(22(18,19)20)14-11-13-8-10(23-11)7-6-9-4-2-1-3-5-9/h1-5,8,12H,6-7H2,(H,13,14)(H2,15,16,17)(H2,18,19,20)
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n/an/a 7.10n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422445
PNG
(CHEMBL318071)
Show SMILES Cc1nccn1CC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H12N2O7P2/c1-5-7-2-3-8(5)4-6(9,16(10,11)12)17(13,14)15/h2-3,9H,4H2,1H3,(H2,10,11,12)(H2,13,14,15)
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n/an/a 10n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422450
PNG
(CHEMBL316663)
Show SMILES CN(CCCCOc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C14H25NO8P2/c1-15(10-5-6-12-23-13-7-3-2-4-8-13)11-9-14(16,24(17,18)19)25(20,21)22/h2-4,7-8,16H,5-6,9-12H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 10n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422478
PNG
(CHEMBL100831)
Show SMILES OP(O)(=O)C(Nc1nccs1)P(O)(O)=O
Show InChI InChI=1S/C4H8N2O6P2S/c7-13(8,9)4(14(10,11)12)6-3-5-1-2-15-3/h1-2,4H,(H,5,6)(H2,7,8,9)(H2,10,11,12)
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n/an/a 18n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422456
PNG
(CHEMBL100232)
Show SMILES OC(CCNCCCSc1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H21NO7P2S/c14-12(21(15,16)17,22(18,19)20)7-9-13-8-4-10-23-11-5-2-1-3-6-11/h1-3,5-6,13-14H,4,7-10H2,(H2,15,16,17)(H2,18,19,20)
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n/an/a 18n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422471
PNG
(CHEMBL102209)
Show SMILES CN(CCCSc1ccc(Cl)cc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H22ClNO7P2S/c1-15(8-2-10-25-12-5-3-11(14)4-6-12)9-7-13(16,23(17,18)19)24(20,21)22/h3-6,16H,2,7-10H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 18n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422436
PNG
(CHEMBL97911)
Show SMILES OC(Cc1ncc[nH]1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-4-6-1-2-7-4/h1-2,8H,3H2,(H,6,7)(H2,9,10,11)(H2,12,13,14)
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n/an/a 18n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422453
PNG
(CHEMBL323300)
Show SMILES Cn1ccnc1NC(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C5H11N3O6P2/c1-8-3-2-6-4(8)7-5(15(9,10)11)16(12,13)14/h2-3,5H,1H3,(H,6,7)(H2,9,10,11)(H2,12,13,14)
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n/an/a 18n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422481
PNG
(CHEMBL318861)
Show SMILES CCCN(CCCOc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C15H27NO8P2/c1-2-10-16(11-6-13-24-14-7-4-3-5-8-14)12-9-15(17,25(18,19)20)26(21,22)23/h3-5,7-8,17H,2,6,9-13H2,1H3,(H2,18,19,20)(H2,21,22,23)
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n/an/a 24n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422474
PNG
(CHEMBL321075)
Show SMILES CCN(CCCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C14H25NO7P2/c1-2-15(11-6-9-13-7-4-3-5-8-13)12-10-14(16,23(17,18)19)24(20,21)22/h3-5,7-8,16H,2,6,9-12H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 39n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422439
PNG
(CHEMBL102185)
Show SMILES CN(CCCCCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C15H27NO7P2/c1-16(12-7-3-6-10-14-8-4-2-5-9-14)13-11-15(17,24(18,19)20)25(21,22)23/h2,4-5,8-9,17H,3,6-7,10-13H2,1H3,(H2,18,19,20)(H2,21,22,23)
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n/an/a 49n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422442
PNG
(CHEMBL323299)
Show SMILES Cc1ncc(CC(O)(P(O)(O)=O)P(O)(O)=O)[nH]1
Show InChI InChI=1S/C6H12N2O7P2/c1-4-7-3-5(8-4)2-6(9,16(10,11)12)17(13,14)15/h3,9H,2H2,1H3,(H,7,8)(H2,10,11,12)(H2,13,14,15)
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n/an/a 51n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422437
PNG
(CHEMBL273286)
Show SMILES OC(CCNCCCc1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H21NO7P2/c14-12(21(15,16)17,22(18,19)20)8-10-13-9-4-7-11-5-2-1-3-6-11/h1-3,5-6,13-14H,4,7-10H2,(H2,15,16,17)(H2,18,19,20)
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n/an/a 56n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422468
PNG
(CHEMBL98787)
Show SMILES OC(Cc1nccn1C(=O)c1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C12H14N2O8P2/c15-11(9-4-2-1-3-5-9)14-7-6-13-10(14)8-12(16,23(17,18)19)24(20,21)22/h1-7,16H,8H2,(H2,17,18,19)(H2,20,21,22)
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n/an/a 65n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422462
PNG
(CHEMBL98211)
Show SMILES OC(CCc1cnc[nH]1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H12N2O7P2/c9-6(16(10,11)12,17(13,14)15)2-1-5-3-7-4-8-5/h3-4,9H,1-2H2,(H,7,8)(H2,10,11,12)(H2,13,14,15)
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n/an/a 67n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422459
PNG
(CHEMBL101717)
Show SMILES CCN(CCCOc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C14H25NO8P2/c1-2-15(10-6-12-23-13-7-4-3-5-8-13)11-9-14(16,24(17,18)19)25(20,21)22/h3-5,7-8,16H,2,6,9-12H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 72n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422480
PNG
(CHEMBL101647)
Show SMILES OC(CCn1ccnc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C6H12N2O7P2/c9-6(16(10,11)12,17(13,14)15)1-3-8-4-2-7-5-8/h2,4-5,9H,1,3H2,(H2,10,11,12)(H2,13,14,15)
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n/an/a 157n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422466
PNG
(CHEMBL318504)
Show SMILES OP(O)(=O)C(Nc1nccn1Cc1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C11H15N3O6P2/c15-21(16,17)11(22(18,19)20)13-10-12-6-7-14(10)8-9-4-2-1-3-5-9/h1-7,11H,8H2,(H,12,13)(H2,15,16,17)(H2,18,19,20)
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n/an/a 185n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422447
PNG
(CHEMBL101716)
Show SMILES CN(CCCOc1ccccc1)CCCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C14H25NO8P2/c1-15(11-6-12-23-13-7-3-2-4-8-13)10-5-9-14(16,24(17,18)19)25(20,21)22/h2-4,7-8,16H,5-6,9-12H2,1H3,(H2,17,18,19)(H2,20,21,22)
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n/an/a 246n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50135841
PNG
((4-methylthiazol-2-ylamino)methylenediphosphonic a...)
Show SMILES Cc1csc(NC(P(O)(O)=O)P(O)(O)=O)n1
Show InChI InChI=1S/C5H10N2O6P2S/c1-3-2-16-4(6-3)7-5(14(8,9)10)15(11,12)13/h2,5H,1H3,(H,6,7)(H2,8,9,10)(H2,11,12,13)
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n/an/a 347n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422443
PNG
(CHEMBL327756)
Show SMILES OP(O)(=O)C(Nc1nccn1-c1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C10H13N3O6P2/c14-20(15,16)10(21(17,18)19)12-9-11-6-7-13(9)8-4-2-1-3-5-8/h1-7,10H,(H,11,12)(H2,14,15,16)(H2,17,18,19)
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n/an/a 600n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422440
PNG
(CHEMBL98080)
Show SMILES CC(C)c1cnc(NC(P(O)(O)=O)P(O)(O)=O)s1
Show InChI InChI=1S/C7H14N2O6P2S/c1-4(2)5-3-8-6(18-5)9-7(16(10,11)12)17(13,14)15/h3-4,7H,1-2H3,(H,8,9)(H2,10,11,12)(H2,13,14,15)
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n/an/a 632n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422460
PNG
(CHEMBL98629)
Show SMILES OP(O)(=O)C(Cc1nccs1)P(O)(O)=O
Show InChI InChI=1S/C5H9NO6P2S/c7-13(8,9)5(14(10,11)12)3-4-6-1-2-15-4/h1-2,5H,3H2,(H2,7,8,9)(H2,10,11,12)
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n/an/a 733n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422451
PNG
(CHEMBL98083)
Show SMILES OC(CCNCCc1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C11H19NO7P2/c13-11(20(14,15)16,21(17,18)19)7-9-12-8-6-10-4-2-1-3-5-10/h1-5,12-13H,6-9H2,(H2,14,15,16)(H2,17,18,19)
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n/an/a 885n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422465
PNG
(CHEMBL97920)
Show SMILES CCCCN(CCCOc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C16H29NO8P2/c1-2-3-11-17(12-7-14-25-15-8-5-4-6-9-15)13-10-16(18,26(19,20)21)27(22,23)24/h4-6,8-9,18H,2-3,7,10-14H2,1H3,(H2,19,20,21)(H2,22,23,24)
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n/an/a 1.18E+3n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422479
PNG
(CHEMBL100717)
Show SMILES OP(O)(=O)C(Nc1ncc[nH]1)P(O)(O)=O
Show InChI InChI=1S/C4H9N3O6P2/c8-14(9,10)4(15(11,12)13)7-3-5-1-2-6-3/h1-2,4H,(H2,5,6,7)(H2,8,9,10)(H2,11,12,13)
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n/an/a 1.95E+3n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422473
PNG
(CHEMBL99006)
Show SMILES OC(Cn1cncn1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C4H9N3O7P2/c8-4(15(9,10)11,16(12,13)14)1-7-3-5-2-6-7/h2-3,8H,1H2,(H2,9,10,11)(H2,12,13,14)
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n/an/a 2.20E+3n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422476
PNG
(CHEMBL101987)
Show SMILES OP(O)(=O)C(Sc1nccs1)P(O)(O)=O
Show InChI InChI=1S/C4H7NO6P2S2/c6-12(7,8)4(13(9,10)11)15-3-5-1-2-14-3/h1-2,4H,(H2,6,7,8)(H2,9,10,11)
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n/an/a 2.40E+3n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422452
PNG
(CHEMBL317338)
Show SMILES CN(CCCCCCc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C16H29NO7P2/c1-17(14-12-16(18,25(19,20)21)26(22,23)24)13-8-3-2-5-9-15-10-6-4-7-11-15/h4,6-7,10-11,18H,2-3,5,8-9,12-14H2,1H3,(H2,19,20,21)(H2,22,23,24)
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n/an/a 3.63E+3n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50422438
PNG
(CHEMBL432388)
Show SMILES CN(CCCCCCOc1ccccc1)CCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C16H29NO8P2/c1-17(13-11-16(18,26(19,20)21)27(22,23)24)12-7-2-3-8-14-25-15-9-5-4-6-10-15/h4-6,9-10,18H,2-3,7-8,11-14H2,1H3,(H2,19,20,21)(H2,22,23,24)
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n/an/a 1.76E+4n/an/an/an/an/an/a



University of Illinois at Urbana-Champaign

Curated by ChEMBL


Assay Description
Negative logarithm of inhibitory concentration against bone resorption


J Med Chem 46: 2932-44 (2003)


Article DOI: 10.1021/jm030054u
BindingDB Entry DOI: 10.7270/Q2R78GHD
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%