Affinity Data by PubMed id=12852955

PubMed code 12852955

Found 25 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131015 (8-Fluoro-1,3,4,5-tetrahydro-2H-benzo[c][1,6]naphth...) Show SMILES Fc1ccc2c3CNCCc3[nH]c(=O)c2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131011 (8-Fluoro-2-(3-piperidin-1-yl-propionyl)-1,3,4,5-te...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131003 (1,3,4,5-Tetrahydro-2H-benzo[c][1,7]naphthyridin-6-...) Show SMILES O=c1[nH]c2CNCCc2c2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131006 (3-(Pyrrolidine-2-carbonyl)-1,3,4,5-tetrahydro-2H-b...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131016 (8-Fluoro-2-[3-(4-pyrrolidin-1-yl-piperidin-1-yl)-p...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131012 (1,3,4,5-Tetrahydro-2H-benzo[c][1,6]naphthyridin-6-...) Show SMILES O=c1[nH]c2CCNCc2c2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131017 (2-(3-Piperidin-1-yl-propionyl)-1,3,4,5-tetrahydro-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131005 (2-(2-Piperidin-1-yl-acetyl)-1,3,4,5-tetrahydro-2H-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131004 ((2S)-2-ammonio-5-oxo-5-(6-oxo-3,4,5,6-tetrahydrobe...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131018 (2-[3-(4-Pyrrolidin-1-yl-piperidin-1-yl)-propionyl]...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131007 (3-[2-(4-Cyclopentyl-piperazin-1-yl)-acetyl]-1,3,4,...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130579 (5H-Benzo[c][1,6]naphthyridin-6-one \| CHEMBL82342) Show SMILES O=c1[nH]c2ccncc2c2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131001 (3-(2-Piperidin-1-yl-acetyl)-1,3,4,5-tetrahydro-2H-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131021 (1,3,4,5-Tetrahydro-2H-phenanthridin-6-one \| CHEMBL...) Show SMILES O=c1[nH]c2CCCCc2c2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130590 (5H-Benzo[c][1,7]naphthyridin-6-one \| CHEMBL311091) Show SMILES O=c1[nH]c2cnccc2c2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131019 (2-[2-(4-Pyrrolidin-1-yl-piperidin-1-yl)-acetyl]-1,...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131022 (2-(2-Piperidin-1-yl-ethanesulfonyl)-1,3,4,5-tetrah...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131020 (3-(3-Piperidin-1-yl-propionyl)-1,3,4,5-tetrahydro-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131009 (3-[3-(4-Pyrrolidin-1-yl-piperidin-1-yl)-propionyl]...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	243	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131010 (3-[2-(4-Pyrrolidin-1-yl-piperidin-1-yl)-ethanesulf...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27500 (5,6-dihydrophenanthridin-6-one \| 5H-Phenanthridin-...) Show SMILES O=c1[nH]c2ccccc2c2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131008 (2-[2-(4-Pyrrolidin-1-yl-piperidin-1-yl)-ethanesulf...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	357	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131002 (3-(2-Piperidin-1-yl-ethanesulfonyl)-1,3,4,5-tetrah...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	376	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131014 (2-(4-Piperidin-1-yl-butyryl)-1,3,4,5-tetrahydro-2H...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	457	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131013 (1,2,3,4,4a,5-hexahydrophenanthridin-6(10bH)-one \| ...) Show SMILES O=C1NC2CCCCC2c2ccccc12 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
Guilford Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%