Affinity Data by PubMed id=12954051

PubMed code 12954051

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50133024 (3-Fluoro-4-[5-(4-methylsulfanyl-phenyl)-3-trifluor...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against human Prostaglandin G/H synthase 2				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against Prostaglandin G/H synthase 1 from ram seminal vesicles				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against human Prostaglandin G/H synthase 2				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50133025 (3-Fluoro-4-[5-(4-methoxy-phenyl)-3-trifluoromethyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against human Prostaglandin G/H synthase 2				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against human Prostaglandin G/H synthase 2				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50133026 (2-Fluoro-4-[5-(4-methoxy-phenyl)-3-trifluoromethyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against human Prostaglandin G/H synthase 2				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against Prostaglandin G/H synthase 1 from ram seminal vesicles				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50133024 (3-Fluoro-4-[5-(4-methylsulfanyl-phenyl)-3-trifluor...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against Prostaglandin G/H synthase 1 from ram seminal vesicles				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50133025 (3-Fluoro-4-[5-(4-methoxy-phenyl)-3-trifluoromethyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against Prostaglandin G/H synthase 1 from ram seminal vesicles				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50133026 (2-Fluoro-4-[5-(4-methoxy-phenyl)-3-trifluoromethyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of the compound against Prostaglandin G/H synthase 1 from ram seminal vesicles				J Med Chem 46: 3975-84 (2003) Article DOI: 10.1021/jm020563g BindingDB Entry DOI: 10.7270/Q2HD7V29
Dr Reddy's Laboratories Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%