Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000534 (2-Phenethyl-6-[3-(pyridin-4-ylsulfanyl)-propyl]-2,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000536 (6-Allyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000526 (2-Phenethyl-6-(3-phenoxy-propyl)-2,3-dihydro-benzo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000551 (4-Allyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000531 (2-(4-Methoxy-benzyl)-3-methyl-6-propyl-2,3-dihydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000535 (3,3-Dimethyl-2-phenethyl-6-(3-phenoxy-propyl)-2,3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000542 (4-[3-(5-Hydroxy-2-phenethyl-2,3-dihydro-benzofuran...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000538 (3,3-Dimethyl-6-propyl-2-[2-(pyridin-2-ylsulfanyl)-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000537 (2-Phenethyl-4-propyl-6-{3-[4-(5H-tetrazol-5-yl)-ph...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000527 (6-[3-(Benzothiazol-2-ylsulfanyl)-propyl]-2-pheneth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000533 (6-Benzyl-2-phenethyl-2,3-dihydro-benzofuran-5-ol |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000545 (8-[3-(5-Hydroxy-2-phenethyl-2,3-dihydro-benzofuran...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000552 (2-[2-(4-Chloro-phenyl)-ethyl]-6-(3-phenoxy-propyl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000524 (6-Allyl-2-[2-(4-methoxy-phenyl)-ethyl]-3,3-dimethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000528 (1-{2-Hydroxy-4-[3-(5-hydroxy-2-phenethyl-2,3-dihyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor 1 (Homo sapiens (Human)) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against LTB4 in human PMN | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000544 (3,3-Dimethyl-2-[2-(4-methylsulfanyl-phenyl)-ethyl]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000525 (2-Phenethyl-6-(3-phenoxy-propyl)-4-propyl-2,3-dihy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000532 (6-Allyl-2-(4-methoxy-benzyl)-3,3-dimethyl-2,3-dihy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 164 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase. | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus) | BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor 1 (Homo sapiens (Human)) | BDBM50000546 (3,4,5,6-Tetrahydroxy-tetrahydro-pyran-2-carboxylic...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre For Therapeutic Research Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity against LTB4 in human PMN | J Med Chem 35: 1299-318 (1992) BindingDB Entry DOI: 10.7270/Q25X27WS | |||||||||||
More data for this Ligand-Target Pair |